- The role of 27-hydroxycholesterol in meta-inflammation
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Son Y, Choi E, Hwang Y, Kim K
- KMID: 2553522
- Korean J Physiol Pharmacol.
- 2024 Mar;28(2):107-112.
- doi: 10.4196/kjpp.2024.28.2.107
27-Hydroxycholesterol (27OHChol), a prominent cholesterol metabolite present in the bloodstream and peripheral tissues, is a kind of immune oxysterol that elicits immune response. Recent research indicates the involvement of 27OHChol... -
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- Transcriptional regulation of genetic variants in the SLC40A1 promoter
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Ha SY, Kim JY, Choi JH
- KMID: 2553523
- Korean J Physiol Pharmacol.
- 2024 Mar;28(2):113-120.
- doi: 10.4196/kjpp.2024.28.2.113
Solute carrier 40A1 (SLC40A1) encodes ferroportin, which is the only known transmembrane protein that exports elemental iron from mammalian cells and is essential for iron homeostasis. Mutations in SLC40A1 are... -
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- Somatodendritic organization of pacemaker activity in midbrain dopamine neurons
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Jang J, Kim SH, Um KB, Kim HJ, Park MK
- KMID: 2553528
- Korean J Physiol Pharmacol.
- 2024 Mar;28(2):165-181.
- doi: 10.4196/kjpp.2024.28.2.165
The slow and regular pacemaking activity of midbrain dopamine (DA) neurons requires proper spatial organization of the excitable elements between the soma and dendritic compartments, but the somatodendritic organization is... -
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- Profiling of endogenous metabolites and changes in intestinal microbiota distribution after GEN-001 (Lactococcus lactis) administration
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Kim MG, Kim S, Jeon JY, Moon SJ, Kwak YG, Na JY, Lee S, Park KM, Kim HJ, Lee SM, Choi SY, Shin KH
- KMID: 2553527
- Korean J Physiol Pharmacol.
- 2024 Mar;28(2):153-164.
- doi: 10.4196/kjpp.2024.28.2.153
This study aimed to identify metabolic biomarkers and investigate changes in intestinal microbiota in the feces of healthy participants following administration of Lactococcus lactis GEN-001. GEN-001 is a single-strain L.... -
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- Exercise alleviates cisplatin-induced toxicity in the hippocampus of mice by inhibiting neuroinflammation and improving synaptic plasticity
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Park SH, Ko JR, Han J
- KMID: 2553526
- Korean J Physiol Pharmacol.
- 2024 Mar;28(2):145-152.
- doi: 10.4196/kjpp.2024.28.2.145
Chemotherapy-induced cognitive impairment is recognized as the most typical symptom in patients with cancer that occurs during and following the chemotherapy treatment. Recently many studies focused on pharmaceutical strategies to... -
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- Effects of gas signaling molecule SO2 in cardiac functions of hyperthyroid rats
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Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
- KMID: 2553525
- Korean J Physiol Pharmacol.
- 2024 Mar;28(2):129-143.
- doi: 10.4196/kjpp.2024.28.2.129
Sulfur dioxide (SO2), a novel endogenous gas signaling molecule, is involved in the regulation of cardiac function. Exerting a key role in progression of hyperthyroidism-induced cardiomyopathy (HTC), myocardial fibrosis is... -
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- Development of a model to predict vancomycin serum concentration during continuous infusion of vancomycin in critically ill pediatric patients
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Han YJ, Jang W, Kim JS, Kim HJ, Suh SY, Cho YS, Park JD, Lee B
- KMID: 2553524
- Korean J Physiol Pharmacol.
- 2024 Mar;28(2):121-127.
- doi: 10.4196/kjpp.2024.28.2.121
Vancomycin is a frequently used antibiotic in intensive care units, and the patient’s renal clearance affects the pharmacokinetic characteristics of vancomycin. Several advantages have been reported for vancomycin continuous intravenous... -
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