- Multiple consecutive-biphasic pulse stimulation improves spatially localized firing of retinal ganglion cells in the degenerate retina
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Ahn J, Yoo Y, Goo YS
- KMID: 2547320
- Korean J Physiol Pharmacol.
- 2023 Nov;27(6):541-553.
- doi: 10.4196/kjpp.2023.27.6.541
Retinal prostheses have shown some clinical success in restoring vision in patients with retinitis pigmentosa. However, the post-implantation visual acuity does not exceed that of legal blindness. The reason for... -
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- Three sesquiterpene lactones suppress lung adenocarcinoma by blocking TMEM16A-mediated Ca2+ -activated Cl− channels
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Xiu R, Jia J, Zhang Q, Liu F, Jia Y, Zhang Y, Song B, Liu X, Chen J, Huang D, Zhang F, Ma J, Li H, Zhang X, Geng Y
- KMID: 2547318
- Korean J Physiol Pharmacol.
- 2023 Nov;27(6):521-531.
- doi: 10.4196/kjpp.2023.27.6.521
Transmembrane protein TMEM16A, which encodes calcium-activated chloride channel has been implicated in tumorigenesis. Overexpression of TMEM16A is associated with poor prognosis and low overall survival in multiple cancers including lung... -
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- Sweroside plays a role in mitigating high glucose-induced damage in human renal tubular epithelial HK-2 cells by regulating the SIRT1/NF-κB signaling pathway
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Ma X, Guo Z, Zhao W, Chen L
- KMID: 2547319
- Korean J Physiol Pharmacol.
- 2023 Nov;27(6):533-540.
- doi: 10.4196/kjpp.2023.27.6.533
Sweroside is a natural monoterpene derived from Swertia pseudochinensis Hara. Recently, studies have shown that sweroside exhibits a variety of biological activities, such as anti-inflammatory, antioxidant, and hypoglycemic effects. However, its... -
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- Cornuside inhibits glucose-induced proliferation and inflammatory response of mesangial cells
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Li X, Guo L, Huang F, Xu W, Peng G
- KMID: 2547317
- Korean J Physiol Pharmacol.
- 2023 Nov;27(6):513-520.
- doi: 10.4196/kjpp.2023.27.6.513
Cornuside is a secoiridoid glucoside compound extracted from the fruits of Cornus officinalis. Cornuside has immunomodulatory and anti-inflammatory properties; however, its potential therapeutic effects on diabetic nephropathy (DN) have not... -
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