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10 results

Heat Acclimatization in Hot Summer for Ten Weeks Suppress the Sensitivity of Sweating in Response to Iontophoretically-administered Acetylcholine

Lee JB

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):349-355.
  • doi: 10.4196/kjpp.2008.12.6.349
To determine the peripheral mechanisms involved in thermal sweating during the hot summers in July before acclimatization and after acclimatization in September, we evaluated the sweating response of healthy subjects...
The Effect of Caffeic Acid on Wound Healing in Skin-incised Mice

Song HS, Park TW, Sohn UD, Shin YK, Choi BC, Kim CJ, Sim SS

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):343-347.
  • doi: 10.4196/kjpp.2008.12.6.343
This study was carried out to investigate the wound healing effect of caffeic acid in skin-incised mice. Caffeic acid showed significant effects on anti-inflammatory activity and wound healing, such as...
Diversity of Ion Channels in Human Bone Marrow Mesenchymal Stem Cells from Amyotrophic Lateral Sclerosis Patients

Park KS, Choi MR, Jung KH, Kim SH, Kim HY, Kim KS, Cha EJ, Kim Y, Chai YG

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):337-342.
  • doi: 10.4196/kjpp.2008.12.6.337
Human bone marrow mesenchymal stem cells (hBM-MSCs) represent a potentially valuable cell type for clinical therapeutic applications. The present study was designed to evaluate the effect of long-term culturing (up...
Decreased Expression of Na+/K+-ATPase, NHE3, NBC1, AQP1 and OAT in Gentamicin-induced Nephropathy

Bae WK, Lee JU, Park JW, Bae EH, Ma SK, Kim SH, Kim SW

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):331-336.
  • doi: 10.4196/kjpp.2008.12.6.331
The present study was aimed to determine whether there is an altered regulation of tubular transporters in gentamicin-induced nephropathy. Sprague-Dawley male rats (200~250 g) were subcutaneously injected with gentamicin (100...
Voltage-dependent Ca2+ Current Identified in Freshly Isolated Interstitial Cells of Cajal (ICC) of Guinea-pig Stomach

Kim YC, Suzuki H, Xu WX, Hashitani , Choi W, Yun HY, Park SM, Youn SJ, Lee SJ, Lee SJ

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):323-330.
  • doi: 10.4196/kjpp.2008.12.6.323
The properties of voltage dependent Ca2+ current (VDCC) were investigated in interstitial cells of Cajal (ICC) distributed in the myenteric layer (ICC-MY) of guinea-pig antrum. In tissue, ICC-MY showed c-Kit...
Eugenol Inhibits ATP-induced P2X Currents in Trigeminal Ganglion Neurons

Li HY, Lee BK, Kim JS, Jung SJ, Oh SB

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):315-321.
  • doi: 10.4196/kjpp.2008.12.6.315
Eugenol is widely used in dentistry to relieve pain. We have recently demonstrated voltage-gated Na+ and Ca2+ channels as molecular targets for its analgesic effects, and hypothesized that eugenol acts...
Functional Connectivity Map of Retinal Ganglion Cells for Retinal Prosthesis

Ye JH, Ryu SB, Kim KH, Goo YS

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):307-314.
  • doi: 10.4196/kjpp.2008.12.6.307
Retinal prostheses are being developed to restore vision for the blind with retinal diseases such as retinitis pigmentosa (RP) or age-related macular degeneration (AMD). Among the many issues for prosthesis...
Long-term Follow-up of Cutaneous Hypersensitivity in Rats with a Spinal Cord Contusion

Jung JI, Kim J, Hong SK, Yoon YW

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):299-306.
  • doi: 10.4196/kjpp.2008.12.6.299
Sometimes, spinal cord injury (SCI) results in various chronic neuropathic pain syndromes that occur diffusely below the level of the injury. It has been reported that behavioral signs of neuropathic...
Forskolin Enhances Synaptic Transmission in Rat Dorsal Striatum through NMDA Receptors and PKA in Different Phases

Cho HS, Lee HH, Choi SJ, Kim KJ, Jeun SH, Li QZ, Sung KW

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):293-297.
  • doi: 10.4196/kjpp.2008.12.6.293
The effect of forskolin on corticostriatal synaptic transmission was examined by recording excitatory postsynaptic currents (EPSCs) in rat brain slices using the whole-cell voltage-clamp technique. Forskolin produced a dose-dependent increase...
Pre-ischemic Treatment with Ampicillin Reduces Neuronal Damage in the Mouse Hippocampus and Neostriatum after Transient Forebrain Ischemia

Lee KE, Kim SK, Cho KO, Kim SY

  • Korean J Physiol Pharmacol.
  • 2008 Dec;12(6):287-291.
  • doi: 10.4196/kjpp.2008.12.6.287
Ampicillin, a beta-lactam antibiotic, has been reported to induce astrocytic glutamate transporter-1 which plays a crucial role in protecting neurons against glutamate excitotoxicity. We investigated the effect of ampicillin on...

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