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Data sharing: a direction for securing research transparency

Nahm FS

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Corrigendum: Synergistic interaction between acetaminophen and L-carnosine improved neuropathic pain via NF-κB pathway and antioxidant properties in chronic constriction injury model

Owoyele BV, Bakare AO, Olaseinde OF, Ochu MJ, Yusuff AM, Ekebafe F, Fogabi OL, Treister R

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Post-COVID-19 pain syndrome: a descriptive study in Turkish population

Topal , Özçelik N, Atayoğlu AT

Background: The new type of corona virus has a wide range of symptoms. Some people who have COVID-19 can experience long-term effects from their infection, known as post-COVID conditions. The...
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Associations of unspecified pain, idiopathic pain and COVID-19 in South Korea: a nationwide cohort study

Kim N, Kim J, Yang BR, Hahm BJ

Background: Few studies have investigated unspecified or idiopathic pain associated with COIVD-19. This study aimed to provide the incidence rates of unspecified pain and idiopathic pain in patients with COVID-19...
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Actual situation and prescribing patterns of opioids by pain physicians in South Korea

Kim MJ, Kim JY, Lim YH, Hong SJ, Jeong JH, Choi HR, Park SK, Kim JE, Lee MK, Kim JH

Background: Use of opioids for chronic intractable pain is increasing globally, and their proper use can improve patients’ quality of life. In contrast, opioid use disorders, such as abuse or...
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Perioperative stress prolong post-surgical pain via miR-339-5p targeting oprm1 in the amygdala

Zhu Y, Sun M, Liu P, Shao W, Xiong M, Xu B

Background: The decreased expression of mu-opioid receptors (MOR) in the amygdala may be a key molecular in chronic post-surgical pain (CPSP). It is known that miR-339-5p expression in the amygdala...
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The role of botulinum toxin type A related axon transport in neuropathic pain induced by chronic constriction injury

Bu H, Jiao P, Fan X, Gao Y, Zhang L, Guo H

Background: The mechanism of peripheral axon transport in neuropathic pain is still unclear. Chemokine ligand 13 (CXCL13) and its receptor (C-X-C chemokine receptor type 5, CXCR5) as well as GABA...
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Evaluation of the antinociceptive effects of a selection of triazine derivatives in mice

Hajhashemi V, Khodarahmi G, Asadi P, Rajabi H

Background: The authors showed in a previous study that some novel triazine derivatives had an anti-inflammatory effect. The present study was designed to evaluate the antinociceptive effect of five out...
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Predictive factors associated with successful response to utrasound guided genicular radiofrequency ablation

Kose SG, Kose HC, Celikel F, Akkaya OT

Background: Ultrasound-guided genicular nerve radiofrequency (RF) procedures are of interest in the management of chronic knee pain. A wide variety of demographic, clinical, and procedural characteristics can affect treatment success....
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Medial prefrontal cortex nitric oxide modulates neuropathic pain behavior through mu opioid receptors in rats

Raisian D, Erfanparast A, Tamaddonfard E, Soltanalinejad-Taghiabad F

Background: The neocortex, including the medial prefrontal cortex (mPFC), contains many neurons expressing nitric oxide synthase (NOS). In addition, increasing evidence shows that the nitric oxide (NO) and opioid systems...
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Stem cells from human exfoliated deciduous teeth attenuate trigeminal neuralgia in rats by inhibiting endoplasmic reticulum stress

Yang Z, Wang C, Zhang X, Li J, Zhang Z, Tan Z, Wang J, Zhang J, Bai X

Background: The treatment of trigeminal neuralgia remains a challenging issue. Stem cells from human exfoliated deciduous teeth (SHED) provide optimized therapy for chronic pain. This study aimed to investigate the mechanisms...
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Development of pre-procedure virtual simulation for challenging interventional procedures: an experimental study with clinical application

Seong H, Yun D, Yoon KS, Kwak JS, Koh JC

Background: Most pain management techniques for challenging procedures are still performed under the guidance of the C-arm fluoroscope although it is sometimes difficult for even experienced clinicians to understand the...
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Spinal orexin A attenuates opioid-induced mechanical hypersensitivity in the rat

Youn Dh, Jun J, Kim TW, Park K

Background: Repeated administration of opioid analgesics for pain treatment can produce paradoxical hyperalgesia via peripheral and/or central mechanisms. Thus, this study investigated whether spinally (centrally) administered orexin A attenuates opioid-induced...
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Prevention, diagnosis, and treatment of opioid use disorder under the supervision of opioid stewardship programs: it’s time to act now

Kim EJ, Hwang EJ, Yoo YM, Kim KH

The third opium war may have already started, not only due to illicit opioid trafficking from the Golden Crescent and Golden Triangle on the international front but also through indiscriminate...
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