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Non-thrombotic ischemic cerebrovascular events related to the use of tyrosine kinase inhibitors in patients with cancer: high-resolution magnetic resonance imaging findings

Sim JE, Park J, Bang OY

The targeted cancer therapies that have been introduced in recent years are directed against cancer-specific molecules and signaling pathways, and thus, they have limited nonspecific toxicities. However, major vascular events,...
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Concept Analysis of Health Literacy for Patients with Cardiovascular Disease using Hybrid Model

Sim JE, Hwang SY

PURPOSE: The purpose of this study is to provide a clear definition of the health literacy for patients with cardiovascular disease by analyzing the dimensions and properties using Hybrid concept...
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Experiences of Overcoming Alcoholism in Alcoholics' Female Spouses Using Al-Anon

Sim JE, Hwang SY

PURPOSE: The aim of this study is to investigate and elucidate actual experiences of alcoholics' spouses using familial social gatherings. METHODS: A total of nine women whose alcoholic husbands were attending...
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Comparison of COBAS AmpliPrep/COBAS TaqMan HCV Qualitative Test v2.0 with COBAS AMPLICOR Hepatitis C Virus Test v2.0 for the Qualitative Detection of Hepatitis C Virus RNA in Korean Clinical Samples

Yoo S, Park Y, Lim HS, Kim YR, Sim JE, Kim HS

  • KMID: 2200490
  • J Lab Med Qual Assur.
  • 2013 Dec;35(2):93-99.
BACKGROUND: We comparatively evaluated the performance of the conventional COBAS Amplicor HCV test v2.0 (CAM; Roche Molecular Systems, USA) and the newly developed COBAS AmpliPrep/COBAS TaqMan HCV test v2.0 (CAP/CTM;...
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A Case of GNE Myopathy Presenting a Rapid Deterioration during Pregnancy

Sim JE, Hong JM, Suh GI, Cho H, Park KS, Sohn EH, Choi YC

BACKGROUND: GNE myopathy is characterized by early-adult-onset distal myopathy sparing quadriceps caused by mutations in the GNE gene encoding UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, an enzyme in the sialic-acid synthesis pathway. CASE REPORT:...
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Clinical Characteristics and Molecular Genetic Analysis of Korean Patients with GNE Myopathy

Sim JE, Park HJ, Shin HY, Nam TS, Kim SM, Choi YC

PURPOSE: Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy is an autosomal recessive neuromuscular disorder characterized by early adult-onset weakness of the distal muscles of the lower limbs. The clinical spectrum of GNE...
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A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection

Sim JE, Lee JB, Cho YN, Suh SH, Kim JK, Lee KY

Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of...
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Application of a Repair Enzyme to STR Analysis of Damaged DNA

Sim JE, Lee HY, Yang WI, Lee SH, Shin KJ

  • KMID: 2250333
  • Korean J Leg Med.
  • 2011 Nov;35(2):114-119.
DNA found at the scene of a crime is often damaged and degraded to small fragments and remained in low quantity. Therefore, there are some difficulties in forensic STR typing...
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Clinical Features of the Patients with Seizures after Doxylamine Succinate Overdose

Cho H, Lee MJ, Sim JE, Kim WJ

  • KMID: 2333417
  • J Korean Epilepsy Soc.
  • 2010 Jun;14(1):6-10.
PURPOSE: Doxylamine succinate is an over-the-counter drug commonly used in the treatment of insomnia. It is in the ethanolamine class of antihistamine and is frequently involved in intentional overdoses. Seizures...
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Facial Diplegia in Plasmodium vivax Malaria

Sim JE, Choi YC, Kim WJ

BACKGROUND: Facial diplegia has diverse etiologies, including viral and bacterial infections such as diphtheria, syphilis and Lyme disease, and also protozoal infection in very rarely cases. CASE REPORT: A 20-year-old male...
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Removal of Intradural-Extramedullary Spinal Cord Tumors with Unilateral Limited Laminectomy

Sim JE, Noh SJ, Song YJ, Kim HD

Total laminectomy for the removal of intradural-extramedullary spinal cord tumors has been used widely, but postoperative complications often develop, such as kyphosis, spinal instability, and persistent back pain. In this...
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Genetic characteristics of 22 Y-STR loci in Koreans

Park MJ, Lee HY, Kim NY, Sim JE, Yang WI, Cho SH, Shin KJ

  • KMID: 2250424
  • Korean J Leg Med.
  • 2007 Nov;31(2):162-170.
To construct a Korean Y-chromosomal STR database for 22 Y-STRs (DYS19, DYS385, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS446, DYS447, DYS448, DYS449, DYS456, DYS458, DYS464, DYS635, and...
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Cystic Hemangiopericytoma in the Third Ventricle

Sim JE, Jeong JS, Choi SS, Choi YM, Kim KU

  • KMID: 1881639
  • J Korean Neurosurg Soc.
  • 2006 Dec;40(6):467-470.
Primary intracranial hemangiopericytoma is rare and resemble meningioma on imaging study. It shows meningeal attachment, and is usually isointense with gray matter on T1-weighted MR image with heterogeneous enhancement and...
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Does Age Influence the Poor Prognosis after Aneurysmal SAH Surgery in Elderly Patients?

Sim JE, Kim HD, Song YJ, Noh SJ

  • KMID: 2189114
  • J Korean Neurosurg Soc.
  • 2006 Nov;40(5):357-362.
OBJECTIVE: The incidence of aneurysmal subarachnoid hemorrhage has been increasing. At the same time, surgical results for elderly patients are unsatisfactory and no guidelines of treatment are available. We carried...
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