Yonsei Med J.
2012 Jul;53(4):856-858. 10.3349/ymj.2012.53.4.856.
A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection
- Affiliations
-
- 1Department of Neurology, Severance Institute for Vascular and Metabolic Research, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. kylee@yuhs.ac
- 2Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
- 3Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
- KMID: 1716889
- DOI: http://doi.org/10.3349/ymj.2012.53.4.856
Abstract
- Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of ADEM associated with hepatitis C virus (HCV) infection with positive serum and cerebrospinal fluid (CSF) anti-HCV antibody. After steroid treatment, neurologic symptoms were improved. Virus triggers autoimmunity or direct viral invasion plays a part in the genesis of ADEM. This is the first reported case of ADEM with anti-HCV antibody in the CSF.
