- Effect of Serotonergic Receptors on the Antinociception of Intrathecal Gabapentin in the Formalin Test of Rats
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Choi JI, Yoo KY, Yoon MH
- KMID: 1946652
- J Korean Pain Soc.
- 2002 Jun;15(1):19-25.
BACKGROUND: Spinal gabapentin actively encounters tissue-injury nociception. Serotonin is involved in the modulation of nociceptive transmission at the spinal level. Gabapentin increases the blood serotonin level. This study was designed... -
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- Analgesic Mechanism of Electroacupuncture in an Arthritic Pain Model of Rats: A Neurotransmitter Study
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Yoo YC, Oh JH, Kwon TD, Lee YK, Bai SJ
- KMID: 1058824
- Yonsei Med J.
- 2011 Nov;52(6):1016-1021.
- doi: 10.3349/ymj.2011.52.6.1016
PURPOSE: We investigated what kinds of neurotransmitters are related with electroacupuncture (EA) analgesia in an arthritic pain model of rats. MATERIALS AND METHODS: One hundred rats were assigned to six groups:... -
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- An inhibitory compound against the interaction between Galpha(s) and the third intracellular loop region of serotonin receptor subtype 6 (5-HT(6)) disrupts the signaling pathway of 5-HT(6)
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Choi YH, Kang H, Lee WK, Kim T, Rhim H, Yu YG
- KMID: 1047084
- Exp Mol Med.
- 2007 Jun;39(3):335-342.
Serotonin receptor subtype 6 (5-HT(6)) is a neurotransmitter receptor, which is involved in various brain functions such as memory and mood. It mediates signaling via the interaction with a stimulatory... -
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- Pharmacological Treatment for Personality Disorders
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Paik KC
- KMID: 2286837
- Korean J Psychopharmacol.
- 2005 May;16(3):208-224.
Up to now, it has been a prevailing concept that psychotherapy rather than pharmacotherpy is the main treatment modality for personality disorders. The use of medication to treat personality disorders... -
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- Guidelines for the Treatment of Irritable Bowel Syndrome
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Kwon JG, Park KS, Park JH, Park JM, Park CH, Lee KJ, Park HJ, Rhee JC, The Korean Society of Neurogastroenterology and Motility
- KMID: 1775839
- Korean J Gastroenterol.
- 2011 Feb;57(2):82-99.
- doi: 10.4166/kjg.2011.57.2.82
Traditional symptom-based therapies of irritable bowel syndrome (IBS) are directed at the relief of individual IBS symptoms, but they are often of limited efficacy in addressing the entire symptom complex.... -
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- A Randomized Double-Blind, Double-Dummy, Multicenter Trial of Azasetron versus Ondansetron to Evaluate Efficacy and Safety in the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy
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Lee HY, Kim HK, Lee KH, Kim BS, Song HS, Yang SH, Kim JH, Kim YH, Kim JG, Kim SW, Kim DW, Kim SY, Park HS
- KMID: 2167650
- Cancer Res Treat.
- 2014 Jan;46(1):19-26.
PURPOSE: This study was conducted to evaluate the efficacy and safety of azasetron compared to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting. MATERIALS AND METHODS: This study was... -
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- Haloperidol and clozapine differentially regulate signals pstream of glycogen synthase kinase 3 in the rat frontal cortex
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Roh MS, Seo MS, Kim Y, Kim SH, Jeon WJ, Ahn YM, Kang UG, Juhnn YS, Kim YS
- KMID: 1047086
- Exp Mol Med.
- 2007 Jun;39(3):353-360.
Glycogen synthase kinase 3 (GSK3) was recently suggested to be a potential target of psychotropics used in psychiatric illnesses such as schizophrenia and bipolar disorder. Relevant studies have found that... -
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- Comparison of Azasetron and Ondansetron for Preventing Postoperative Nausea and Vomiting in Patients Undergoing Gynecological Laparoscopic Surgery
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Yun MJ, Kim YH, Kim AR
- KMID: 1779611
- Yonsei Med J.
- 2010 Jan;51(1):88-92.
- doi: 10.3349/ymj.2010.51.1.88
PURPOSE: We compared the prophylactic effects of intravenously administered azasetron (10 mg) and ondansetron (8 mg) on postoperative nausea and vomiting (PONV) in patients undergoing gynecological laparoscopic surgery under general... -
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