- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Treatment of Patients with Decompensated Cirrhosis
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Gwak GY
- KMID: 2373413
- Korean J Gastroenterol.
- 2016 Mar;67(3):137-141.
- doi: 10.4166/kjg.2016.67.3.137
HCV-related decompensated liver cirrhosis is a life-threatening illness with an average 5-year survival rate of 50%. Because these patients have higher risk of morbidity and mortality including development of hepatocellular... -
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- The Impact of Inosine Triphosphatase Variants on Hemoglobin Level and Sustained Virologic Response of Chronic Hepatitis C in Korean
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Kim JS, Ahn SM, Jung YK, Kwon OS, Kim YS, Choi DJ, Kim JH
- KMID: 1793028
- J Korean Med Sci.
- 2013 Aug;28(8):1213-1219.
- doi: 10.3346/jkms.2013.28.8.1213
Two variants of the inosine triphosphatase (ITPA: rs1127354, rs7270101) gene cause ITPA deficiency and protect against the hemolytic toxicity of ribavirin. We investigated the clinical significance of ITPA variants in... -
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- Acute pancreatitis associated with pegylated interferon-alpha-2a therapy in chronic hepatitis C
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Choi JW, Lee JS, Paik WH, Song TJ, Kim JW, Bae WK, Kim KA, Kim JG
- KMID: 2363035
- Clin Mol Hepatol.
- 2016 Mar;22(1):168-171.
- doi: 10.3350/cmh.2016.22.1.168
Chronic hepatitis C virus (HCV) infection is a major cause of liver cirrhosis and hepatocellular carcinoma. Combination therapy of pegylated interferon-alpha (PEG-IFN-α) and ribavirin (RBV) is a current standard treatment... -
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- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Indications for Treatment
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Kim KA
- KMID: 2373410
- Korean J Gastroenterol.
- 2016 Mar;67(3):123-126.
- doi: 10.4166/kjg.2016.67.3.123
The landscape of treatment for HCV infection has evolved substantially with the advent of highly effective direct-acting antiviral agents (DAA). The Korean Association for the Study of the Liver updated... -
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- Review: Clinical Outcome after Living Donor Liver Transplantation in Patients with Hepatitis C Virus-associated Cirrhosis
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Kim HJ
- KMID: 1776824
- Korean J Hepatol.
- 2007 Dec;13(4):489-494.
- doi: 10.3350/kjhep.2007.13.4.489
No abstract available. -
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- Association of IL28B Genotypes and Baseline Serum Interferon-γ-Inducible-Protein-10 Levels with Treatment Response in Hepatitis C Virus Patients in China
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Zhang R, Shao C, Huo N, Li M, Xu X
- KMID: 2411973
- Gut Liver.
- 2016 May;10(3):446-455.
- doi: 10.5009/gnl15162
BACKGROUND/AIMS: Several studies have demonstrated that serum interferon-γ-inducible-protein-10 (IP-10) levels at baseline and single nucleotide polymorphisms (SNPs) near the IL28B gene were associated with viral response and treatment outcomes. Our... -
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- Advanced fibrosis is not a negative pretreatment predictive factor for genotype 2 or 3 chronic hepatitis C patients
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Lee HS, Kweon YO, Tak WY, Park SY, Kang EJ, Lee YL, Yang HM, Park HW
- KMID: 1776802
- Clin Mol Hepatol.
- 2013 Jun;19(2):148-155.
- doi: 10.3350/cmh.2013.19.2.148
BACKGROUND/AIMS: Chronic hepatitis C patients with advanced fibrosis have unsatisfactory sustained virological response (SVR) rates. Few data demonstrating the efficacy of combination therapy in chronic hepatitis C patients with advanced... -
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- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Treatment of Chronic Hepatitis C Genotype 2 and 3
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Jung YK
- KMID: 2373412
- Korean J Gastroenterol.
- 2016 Mar;67(3):132-136.
- doi: 10.4166/kjg.2016.67.3.132
Ever since direct-acting antiviral agents (DAA) have been approved and released into the world, numerous studies on the efficacy, adverse effects and drug-drug interactions of interferon-free DAA combination therapy have... -
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- Prevalence, Risk Factors and Clinical Characteristics in Patients with Genotype 6 Chronic Hepatitis C: A Single Institute Experience
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Shin SK, Park SY, Jung YK, Kim EJ, Lee HN, Lee JJ, Kwon OS, Choi DJ, Kim YS, Kim JH
- KMID: 2373191
- Korean J Gastroenterol.
- 2015 Feb;65(2):105-111.
- doi: 10.4166/kjg.2015.65.2.105
BACKGROUND/AIMS: Hepatitis C genotypes 1 and 2 are widely distributed globally. In contrast, genotype 6 is found mainly in Southeast Asia, while genotype 6 is rare in Korea. This study... -
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- Sofosbuvir-based therapy for patients with chronic hepatitis C: Early experience of its efficacy and safety in Korea
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Cho Y, Cho EJ, Lee JH, Yu SJ, Yoon JH, Kim YJ
- KMID: 2359817
- Clin Mol Hepatol.
- 2015 Dec;21(4):358-364.
- doi: 10.3350/cmh.2015.21.4.358
BACKGROUND/AIMS: The previous standard treatment for chronic hepatitis C (CHC) patients, comprising a combination of pegylated interferon (IFN) and ribavirin, was associated with suboptimal efficacy and severe adverse reactions. A... -
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- Predicting Liver-Related Events Using Transient Elastography in Chronic Hepatitis C Patients with Sustained Virological Response
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Lee HW, Chon YE, Kim SU, Kim BK, Park JY, Kim DY, Ahn SH, Jung KS, Park YN, Han KH
- KMID: 2411971
- Gut Liver.
- 2016 May;10(3):429-436.
- doi: 10.5009/gnl15021
BACKGROUND/AIMS: Few studies have investigated prognostic factors for the development of liver-related events (LREs) in patients with chronic hepatitis C (CHC) who achieve sustained virological response (SVR). METHODS: We analyzed 190... -
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- Clinical Outcome after Living Donor Liver Transplantation in Patients with Hepatitis C Virus-associated Cirrhosis
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Park JI, Choi KM, Lee SG, Hwang S, Kim KH, Ahn CS, Moon DB, Chung YH, Lee YS, Suh DJ
- KMID: 1776830
- Korean J Hepatol.
- 2007 Dec;13(4):543-555.
- doi: 10.3350/kjhep.2007.13.4.543
BACKGROUND AND AIMS: Hepatitis C virus (HCV)-associated cirrhosis is an increasingly frequent indication for liver transplantation (LT). However, HCV recurrence is universal and this immediately occurs following LT, which... -
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- Mutations within the interferon sensitivity determining region in Korean patients infected with hepatitis C virus genotype 1b
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Jin YJ, Park YK, Yun GJ, Lee HC, Jeong SH, Kim GM, Lim YS, Chung YH, Lee YS, Suh DJ
- KMID: 1792594
- Korean J Hepatol.
- 2010 Jun;16(2):158-167.
- doi: 10.3350/kjhep.2010.16.2.158
BACKGROUND/AIMS: The treatment response to interferon could differ with mutations in the interferon-sensitivity-determining region (ISDR) in patients infected with hepatitis C virus (HCV) genotype-1b (HCV-Ib). We examined the pattern of... -
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- Management of direct antiviral agent failures
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Buti M, Esteban R
- KMID: 2373146
- Clin Mol Hepatol.
- 2016 Dec;22(4):432-438.
- doi: 10.3350/cmh.2016.0107
The current standard of care for patients with chronic hepatitis C virus (HCV) infection is a combination of direct-acting antiviral agents (DAAs). Most HCV patients treated with these drugs achieve... -
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- Clinical Utility of a New Automated Hepatitis C Virus Core Antigen Assay for Prediction of Treatment Response in Patients with Chronic Hepatitis C
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Kim MN, Kim HS, Kim JK, Kim BK, Kim SU, Park JY, Kim DY, Ahn SH, Han KH
- KMID: 2468276
- J Korean Med Sci.
- 2016 Sep;31(9):1431-1437.
- doi: 10.3346/jkms.2016.31.9.1431
Hepatitis C virus core antigen (HCV Ag) is a recently developed marker of hepatitis C virus (HCV) infection. We investigated the clinical utility of the new HCV Ag assay for... -
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- No association between the IL28B SNP and response to peginterferon plus ribavirin combination treatment in Korean chronic hepatitis C patients
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Heo NY, Lim YS, Lee W, Oh M, An J, Lee D, Shim JH, Kim KM, Lee HC, Lee YS, Suh DJ
- KMID: 1788567
- Clin Mol Hepatol.
- 2014 Jun;20(2):177-184.
- doi: 10.3350/cmh.2014.20.2.177
BACKGROUND/AIMS: There are few available data regarding the association between the single nucleotide polymorphisms (SNPs) of the gene encoding interleukin 28B (IL28B) and a sustained virologic response (SVR) to peginterferon... -
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