- Hyaluronic acid has chondroprotective and joint-preserving effects on LPS-induced synovitis in horses
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Neuenschwander HM, Moreira JJ, Vendruscolo CP, Fülber J, Seidel SR, Michelacci YM, Baccarin R
- KMID: 2464083
- J Vet Sci.
- 2019 Nov;20(6):e67.
- doi: 10.4142/jvs.2019.20.e67
The intra-articular use of hyaluronic acid (HA) for the treatment of synovitis and osteoarthritis is still controversial. As a consequence, corticosteroids remain the most frequently employed therapeutic agents, despite their... -
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- Neutrophil oxidative burst as a diagnostic indicator of IgG-mediated anaphylaxis
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Won DI, Kim S, Lee EH
- KMID: 2429304
- Blood Res.
- 2018 Dec;53(4):299-306.
- doi: 10.5045/br.2018.53.4.299
BACKGROUND: IgG-mediated anaphylaxis occurs after infusion of certain monoclonal antibody-based therapeutics. New in vitro tests are urgently needed to diagnose such reactions. We investigated whether allergens trigger neutrophil oxidative burst... -
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- Evaluation of Platelet-Rich Plasma and Neutrophil Antimicrobial Extract as Two Autologous Blood-Derived Agents
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Szponder T, Wessely-Szponder J, Smolira A
- KMID: 2395085
- Tissue Eng Regen Med.
- 2017 Jun;14(3):287-296.
- doi: 10.1007/s13770-017-0035-4
The platelet-rich plasma (PRP) and antimicrobial peptides neutrophil extract (AMP extract) were prepared from rabbit neutrophils as two autologous blood-derived preparations, which could be applied locally to enhance healing process... -
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- Characterization of Lactobacillus reuteri BCLR-42 and Lactobacillus plantarum BCLP-51 as novel dog probiotics with innate immune enhancing properties
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Kim EJ, Kang YI, Bang TI, Lee MH, Lee SW, Choi IS, Song CS, Lee JB, Park SY
- KMID: 2368747
- Korean J Vet Res.
- 2016 Jun;56(2):75-84.
- doi: 10.14405/kjvr.2016.56.2.75
Probiotics that are able to provide beneficial effects on animal health have become important ingredients of dog foods. This study was conducted to characterize the probiotic potentials of two strains,... -
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- Phenotypic and Functional Analysis of HL-60 Cells Used in Opsonophagocytic-Killing Assay for Streptococcus pneumoniae
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Kim KH, Seoh JY, Cho SJ
- KMID: 2129643
- J Korean Med Sci.
- 2015 Feb;30(2):145-150.
- doi: 10.3346/jkms.2015.30.2.145
Differentiated HL-60 is an effector cell widely used for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. We investigated the correlation between phenotypic expression of immunoreceptors and phagocytic... -
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- Respiratory epithelial cell lines exposed to anoxia produced inflammatory mediator
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Shahriary , Chin TW, Nussbaum E
- KMID: 2133908
- Anat Cell Biol.
- 2012 Dec;45(4):221-228.
- doi: 10.5115/acb.2012.45.4.221
Human epithelial cell lines were utilized to examine the effects of anoxia on cellular growth and metabolism. Three normal human epithelial cells lines (A549, NHBE, and BEAS-2B) as well as... -
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- The effect of conglutinin on production of reactive oxygen species in bovine granulocytes
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Dec M, Wernicki A, Puchalski , Urban-Chmiel R, Wasko A
- KMID: 1365000
- J Vet Sci.
- 2012 Mar;13(1):33-38.
- doi: 10.4142/jvs.2012.13.1.33
Conglutinin is a high molecular-weight lectin originally detected in bovine serum. It belongs to the family of collectins that bind sugar residues in a Ca(2+)-dependent manner and are effector molecules... -
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- A Study on the Mechanism of Immunomodulating Effects of Moxifloxacin in Oleic Acid-Induced Acute Lung Injury
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Lee YM
- KMID: 1846416
- Tuberc Respir Dis.
- 2011 Aug;71(2):97-105.
- doi: 10.4046/trd.2011.71.2.97
BACKGROUND: It was hypothesized that the immunomodulating effects of moxifloxacin contribute to ameliorate oleic acid (OA)-induced acute lung injury (ALI) by suppression of cytosolic phospholipase A2 (cPLA2). This was based... -
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- Moxifloxacin Alleviates Oleic Acid-provoked Neutrophilic Respiratory Burst in the Rat Lung through the Inhibition of Cytosolic Phospholipase A2
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Lee YM
- KMID: 2114619
- Tuberc Respir Dis.
- 2010 Oct;69(4):256-264.
- doi: 10.4046/trd.2010.69.4.256
BACKGROUND: According to the notion of the immunoregulatory functions of moxifloxacin (MFX), the effect of MFX on the neutrophilic respiratory burst in conjunction with the expression of cytosolic phospholipase A2... -
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- Moxifloxacin Ameliorates Oleic Acid-induced Acute Lung Injury by Modulation of Neutrophilic Oxidative Stress in Rats
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Kim BY, Lee YM
- KMID: 1458042
- Tuberc Respir Dis.
- 2010 Jun;68(6):334-344.
- doi: 10.4046/trd.2010.68.6.334
BACKGROUND: Based on the known immunoregulatory functions of moxifloxacin on phagocytes, the therapeutic effect of moxifloxacin on oleic acid (OA)-induced acute lung injury (ALI) was investigated. METHODS: Moxifloxacin (10 mg/kg) was... -
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- Role of the PLA2-Activated Neutrophilic Oxidative Stress in Oleic Acid-Induced Acute Lung Injury
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Lee YM, Kim BY, Park YY
- KMID: 2050585
- Tuberc Respir Dis.
- 2010 Feb;68(2):55-61.
- doi: 10.4046/trd.2010.68.2.55
BACKGROUND: The underlying pathogenesis of fat embolism-induced acute lung injury (ALI) has not been elucidated. In the present study, the pathogenesis of fat embolism-induced ALI was probed in association with... -
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- Non-specific Immune Response of Rainbow Trout (Oncorhynchus Mykiss) by Dietary Heat-inactivated Potential Probiotics
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Choi SH, Yoon TJ
- KMID: 2163195
- Immune Netw.
- 2008 Sep;8(3):67-74.
- doi: 10.4110/in.2008.8.3.67
BACKGROUND: The effects of the dietary administration of two heat-inactivated whole bacteria from the Vibrionaceae family, singly or combined, on innate immune response of the rainbow trout were studied. The... -
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- Cytosolic Phospholipase A2 Activity in Neutrophilic Oxidative Stress of Platelet-activating Factor-induced Acute Lung Injury
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Kwon YS, Hyun DS, Lee YM
- KMID: 2318980
- Tuberc Respir Dis.
- 2007 Dec;63(6):497-506.
BACKGROUND: The present investigation was performed in rats and isolated human neutrophils in order to confirm the presumptive role of the positive feedback loop of cytosolic phospholipase A2 (cPLA2) activation... -
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- A Case of Chronic Neutrophilic Leukemia with Multiple Myeloma and an Increased Function of Her Neutrophils
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Kim S, Park CJ, Lee KH, Jang S, Chi HS, Seo EJ
- KMID: 2083513
- Korean J Hematol.
- 2007 Jun;42(2):151-156.
- doi: 10.5045/kjh.2007.42.2.151
We describe here a 64-year-old woman who simultaneously presented with chronic neutrophilic leukemia (CNL) and multiple myeloma (MM). The patient presented with mature neutrophilic leukocytosis, hepatosplenomegaly, the absence of Philadelphia... -
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- Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 after Administration of Endotoxin in Diabetic Rats
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Seo KH, Choi JS, Na JO, Uh ST, Kim YH, Park CS
- KMID: 1970265
- Tuberc Respir Dis.
- 2006 Sep;61(3):256-264.
- doi: 10.4046/trd.2006.61.3.256
BACKGROUND: An acute lung injury(ALI) is characterized by the recruitment, activation, and apoptosis of inflammatory cells, numerous products released by inflammatory cells such as reactive oxygen species, inflammatory mediators, and... -
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- Age-Related Decrease and a Simple Flow Cytometric Assay of Neutrophil Function
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Won DI, Heo WB, Suh JS
- KMID: 2038262
- Korean J Lab Med.
- 2005 Aug;25(4):273-279.
BACKGROUND: We intended to confirm a decline in neutrophil function with aging and to devise a simple neutrophil function test protocol for use in a clinical setting. Reversely, the reliability... -
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- Neutrophil Apoptosis and H2O2 Release by LPS in Diabetics
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Seo KH, Na JO, Moon SH, Uh ST, Kim YH, Park CS
- KMID: 1656514
- Tuberc Respir Dis.
- 2004 Sep;57(3):250-256.
- doi: 10.4046/trd.2004.57.3.250
BACKGROUND: Bacterial infections in diabetic patients are an important cause of increased morbidity and mortality. It has been reported that bacterial infections in diabetics showed more impaired PMN functions such... -
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- Increased Reactive Oxygen Species Production by Peripheral Blood Mononuclear Leukocytes, not by Polymorphonuclear Leukocytes, in Atopic Dermatitis
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Huh EJ, Ryu KH, Huh JK, Yoon JS, Kim YH, Kim JT, Hahn H, Lee KH, Lee JS
- KMID: 2314310
- Pediatr Allergy Respir Dis.
- 2004 Mar;14(1):53-61.
PURPOSE: Reactive oxygen species (ROS) are known as a potential mediators that sustain chronic inflammation in atopic dermatitis (AD). To determine the role of peripheral blood mononuclear leukocytes (MO) and... -
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- Hydrogen Peroxide Modulates Phospholipase A2 Aactivity and Endogenous Oxidative Stress in the Free Radical Induced Acute Lung Injury
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Bae CH, Kang HS, Lee S, Jheon SH, Ahn WS, Kwon OC
- KMID: 2288967
- Korean J Thorac Cardiovasc Surg.
- 2002 May;35(5):343-349.
BACKGROUND: In an attempt to investigate the role of oxidants in the activation of phospholipase A2(PLA2) and endogenous oxidative stress in the lung, acute inflammatory lung injury was induced by... -
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- Phospholipase A2 Contributes to Hemorrhage-induced Acute Lung Injury Through Neutrophilic Respiratory Burst
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Jang YS, Kim SE, Jheon SH, Shin TR, Lee YM
- KMID: 2160039
- Tuberc Respir Dis.
- 2001 Dec;51(6):503-516.
- doi: 10.4046/trd.2001.51.6.503
BACKGROUND: The present study was carried out in association with neutrophilic respiratory burst in the lung in order to clarify the pathogenesis of acute respiratory distress syndrome(ARDS) following acute severe... -
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