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The Sysmex XN-2000 Hematology Autoanalyzer Provides a Highly Accurate Platelet Count than the Former Sysmex XE-2100 System Based on Comparison with the CD41/CD61 Immunoplatelet Reference Method of Flow Cytometry

Park SH, Park CJ, Kim MJ, Han MY, Lee BR, Cho YU, Jang S

No abstract available.
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Polymorphonuclear leukocyte functions enhanced by chemotaxis

Hong YS

Human polymorphonuclear leukocytes (PMN) migrate into tissues in response to chemoattractants, yet it is not known whether this process alters the functional capabilities of the PMN. Using recombinant human...
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The Effect of rhG-CSF and rhGM-CSF on Expression of Fc gamma Receptors and beta2 Integrin and Respiratory Burst Function in Human Granulocytes

Kim KH, Ryu KH, Seoh JY

  • KMID: 2335525
  • J Korean Pediatr Soc.
  • 2001 Apr;44(4):397-404.
PURPOSE: Receptors for the Fc of IgG(FcvR) and a beta2 integrin molecule, CD11c/CD18 are important in clearance of microbes by granulocytes. We performed an in vitro study on the effect...
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Phenotypic and Functional Analysis of HL-60 Cells Used in Opsonophagocytic-Killing Assay for Streptococcus pneumoniae

Kim KH, Seoh JY, Cho SJ

Differentiated HL-60 is an effector cell widely used for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. We investigated the correlation between phenotypic expression of immunoreceptors and phagocytic...
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Targeted resequencing of candidate genes reveals novel variants associated with severe Behcet's uveitis

Kim SJ, Lee S, Park C, Seo JS, Kim JI, Yu HG

  • KMID: 2154268
  • Exp Mol Med.
  • 2013 Oct;45(10):e49.
Behcet's disease (BD) is a chronic systemic inflammatory disorder characterized by four major manifestations: recurrent uveitis, oral and genital ulcers and skin lesions. To identify some pathogenic variants associated with...
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Prostaglandin E1 Inhibits CD64 (Fc gamma RI) Expression on Monocyte in Cultured Peripheral Blood Mononuclear Cells

Park JK, Shin HJ, Kim DK, Shin JH, Park DG, Jun HJ, Ryu JW, Chung M, Cho JT, Kim JW, Kim JT

  • KMID: 2096989
  • J Korean Soc Transplant.
  • 1999 Dec;13(2):221-228.
CD64 (Fc gamma RI) is the one of the three Fc gamma receptors on monocytes and represents a high affinity immunoglobin G receptor. CD64 is rapidly upregulated on monocyte in...
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Possible roles of LFA-1 and Fc gamma receptors on the functional immaturities of cord blood polymorphonuclear leukocytes

Kim NA, Choi IH, Shin JS, Park SK, Kim NS, Choi DH, Kim SJ

The functional immaturity of PMNs is one of the major causes of overwhelming sepsis in newborns. In this study, we observed functions and surface markers of PMNs to investigate what...
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CD64 Expression Is Increased in Patients with Severe Acute Pancreatitis: Clinical Significance

Zhang H, Ling XL, Wu YY, Lu MH, Guo H, Zhang PB, Zhao XY, Yang SM

  • KMID: 1792370
  • Gut Liver.
  • 2014 Jul;8(4):445-451.
BACKGROUND/AIMS: Upregulated CD64 expression on neutrophils is the most useful marker for acute bacterial infections and systemic inflammation. However, it is unknown whether CD64 is involved in the pathogenesis of...
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Frequency of FCGR3B Alleles in Thai Blood Donors

Kaset C, Leetrakool N, Intharanut K, Nathalang

BACKGROUND: Human neutrophil antigens (HNAs) are involved in autoimmune and alloimmune neutropenia and transfusion-related acute lung injury. The HNA-1 system is important in immunogenetics, and allele frequencies have been described...
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Selective inhibition of polymorphonuclear leukocytes by immunosuppressive concentration of prostaglandin E2

Hong YS

Prostaglandin E2(PGE2) has been implicated as an immunosuppressive agent and plasma levels of PGE2 are elevated in patients sustaining thermal injury. We examined the effect of 10(-7) M prostaglandin E2(PGE2)...
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Delayed Human Neutrophil Apoptosis by Trichomonas vaginalis Lysate

Song HO, Lim YS, Moon SJ, Ahn MH, Ryu JS

Neutrophils play an important role in the human immune system for protection against such microorganisms as a protozoan parasite, Trichomonas vaginalis; however, the precise role of neutrophils in the pathogenesis...
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Involvement of Src Family Tyrosine Kinase in Apoptosis of Human Neutrophils Induced by Protozoan Parasite Entamoeba histolytica

Sim S, Yu JR, Lee YA, Shin MH

Tyrosine kinases are one of the most important regulators for intracellular signal transduction related to inflammatory responses. However, there are no reports describing the effects of tyrosine kinases on neutrophil...
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Enhanced neutrophil functions by recombinant human granulocyte colony-stimulating factor in diabetic patients with foot infections in vitro

Peck KR, Son DW, Song JH, Kim S, Oh MD, Choe KW

This study was performed to evaluate the effect of granulocyte-colony stimulating factor on neutrophil functions in diabetic patients with active foot infections in vitro. Twelve diabetic patients with foot infections...
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Peripheral blood lymphocyte subsets in patients with stomach cancer

Hong WS, Min YI, Son YS, Hong SI

The present study was conducted in order to investigate the immunologic alterations alongside the numerical changes in peripheral blood lymphocytes(PBL) and their subsets in stomach cancer patients. Lymphocyte surface markers...
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Association Between FcgammaR IIa and IIIa Polymorphism and Clinical Manifestations in Korean Patients with Adult-Onset Still's Disease

Oh YB, Ahn JY, Lee HS, Kim TH, Jun JB, Jung SS, Bae SC, Kim SY, Yoo DH

High-dose intravenous immunoglobulins alter the disease activity of adult-onset Still's disease (AOSD). Because activation status of FcgammaR is possibly dependent on their genetic polymorphisms, we investigated whether the polymorphisms of...
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Mucosal mast cell-derived chondroitin sulphate levels in and worm expulsion from FcRgamma-knockout mice following oral challenge with Strongyloides venezuelensis

Onah DN, Nawa Y

  • KMID: 1099835
  • J Vet Sci.
  • 2004 Sep;5(3):221-226.
Mucosal mast cell-derived chondroitin sulphates (sulphated proteoglycans) were assayed in gut washings and homogenate of FcRgamma-knockout (KO) and wild-type (WT) C57BL/6 mice challenged with Strongyloides venezuelensis in order to assess...
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