Ann Lab Med.  2014 Nov;34(6):471-474. 10.3343/alm.2014.34.6.471.

The Sysmex XN-2000 Hematology Autoanalyzer Provides a Highly Accurate Platelet Count than the Former Sysmex XE-2100 System Based on Comparison with the CD41/CD61 Immunoplatelet Reference Method of Flow Cytometry

• Park SH
• Park CJ
• Kim MJ
• Han MY
• Lee BR
• Cho YU
• Jang S

• KMID: 2129575
• DOI: http://doi.org/10.3343/alm.2014.34.6.471

Abstract

No abstract available.

MeSH Terms

Adolescent
Adult
Aged
Aged, 80 and over
Automation
Blood Platelets/*cytology/metabolism
Child
*Flow Cytometry
Humans
Integrin beta3/*metabolism
Middle Aged
Platelet Count/*instrumentation
Receptors, IgG/*metabolism
Young Adult
Integrin beta3
Receptors, IgG

Figure

• 

  Fig. 1 Results of the CD41/CD61 immunoplatelet reference method using flow cytometry (A). Plots of the correlation analysis between the platelet count measured by the Sysmex XE-2100 hematology autoanalyzer (Sysmex, Kobe, Japan) and the platelet count estimated by the CD41/CD61 immunoplatelet reference method (flow-based platelet counts) (B), and between the Sysmex XN-2000 hematology autoanalyzer (Sysmex) and the platelet count estimated by the CD41/CD61 immunoplatelet reference method (C). The regression equations, correlation coefficients, and coefficients of determination calculated from the results with the two analyzers are included in the figure. Bland-Altman plots comparing the platelet counts and the flow-based platelet counts measured by the two analyzers as a reference method (D-G). Plots of all 195 samples (D for the Sysmex XE-2100, E for the Sysmex XN-2000), and plots of 48 thrombocytopenic samples with platelet counts less than 20.0×109/L (F for the Sysmex XE-2100, G for the Sysmex XN-2000).Abbreviations: RBC, red blood cell; SSC-A, side scattering-area; FSC-H, forward scattering-height; PLT, platelet; XE PLT, platelet count measured directly using the XE-2100; XN PLT, platelet count measured using the XN-2000.

Reference

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