- The Role of Endothelin Receptor A during Myelination of Developing Oligodendrocytes
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Jung KJ, Kim DW, Lee HN, Lee YS, Lee SJ, Che JH, Lee YH, Kang BC
- KMID: 1777982
- J Korean Med Sci.
- 2011 Jan;26(1):92-99.
- doi: 10.3346/jkms.2011.26.1.92
Endothelin (ET)-1 and its receptors (ETA and ETB receptor) are present in the central nervous system. ET exerts biological effects on gliogenesis and glial cell functions. In order to define... -
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- A Case of Sustained Severe Pulmonary Hypertension after Sugrical Repair of Atrial Septal Defect in a Patient with HIV Infection
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Kim WS, Park SH, Choi HJ, Han JJ
- KMID: 1457279
- J Korean Soc Hypertens.
- 2010 Sep;16(3):35-40.
We report a case of severe pulmonary hypertension in a patient with human immunodeficiency virus(HIV) infection. A 29-year-old woman with asymptomatic HIV infection was diagnosed as atrial septal defect(ASD) and... -
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- Effects of Endothelin A Receptor Antagonist to Cellular Proliferation and Apoptosis in Neonatal Rat Heart
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Choi BM, Yoo KH, Hong YS, Lee JW, Kim SK
- KMID: 2335742
- J Korean Pediatr Soc.
- 2003 Jul;46(7):668-678.
PURPOSE: In order to investigate the role of endothelins in the cardiac development, the present study was designed to examine the effects of endothelin A receptor(ETAR) antagonist to the cellular... -
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- The Effect of Nonspecific Endothelin-1 Receptor Blocker (Bosentan®) on Paraquat Induced Pulmonary Fibrosis in Rat
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Jeong HC, Jung KH, Kim BG, Lee SH, Kim MK, Kim CY, Park SM, Lee SH, Shin C, Cho JY, Yoo SH, Kang KH
- KMID: 2318298
- Tuberc Respir Dis.
- 2001 Feb;50(2):182-195.
- doi: 10.4046/trd.2001.50.2.182
BACKGROUND: Idiopathic pulmonary fibrosis(IPF) is a devastating illness for which there is little effective treatment. The key cytokines currently implicated in the fibrotic process are the transforming growth factor-β1(TGF-β1), tumor... -
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- Endothelin A Receptor Blockade Influences Apoptosis and Cellular Proliferation in the Developing Rat Kidney
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Yoo KH, Yim HE, Jang GY, Bae IS, Choi BM, Hong YS, Lee JW
- KMID: 1794420
- J Korean Med Sci.
- 2009 Feb;24(1):138-145.
- doi: 10.3346/jkms.2009.24.1.138
Endothelin systems are believed to play important roles in the emergence and maintenance of functions of various organs during perinatal development, including the kidney. The present study was designed to... -
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- Effect of Small Hairpin RNA Targeting Endothelin-Converting Enzyme-1 in Monocrotaline-Induced Pulmonary Hypertensive Rats
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Son JS, Kim KC, Kim BK, Cho MS, Hong YM
- KMID: 2157974
- J Korean Med Sci.
- 2012 Dec;27(12):1507-1516.
- doi: 10.3346/jkms.2012.27.12.1507
The purpose of this study was to investigate the therapeutic effects of small hairpin RNA (shRNA) targeting endothelin-converting enzyme (ECE)-1 in monocrotaline (MCT)-induced pulmonary hypertensive rats. Ninty-four Sprague-Dawley rats were... -
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- The Effect of Umbilical Cord Blood Derived Mesenchymal Stem Cells in Monocrotaline-induced Pulmonary Artery Hypertension Rats
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Lee H, Lee JC, Kwon JH, Kim KC, Cho MS, Yang YS, Oh W, Choi SJ, Seo ES, Lee SJ, Wang TJ, Hong YM
- KMID: 2155470
- J Korean Med Sci.
- 2015 May;30(5):576-585.
- doi: 10.3346/jkms.2015.30.5.576
Pulmonary arterial hypertension (PAH) causes right ventricular failure due to a gradual increase in pulmonary vascular resistance. The purposes of this study were to confirm the engraftment of human umbilical... -
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