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The Role of MicroRNAs in Oncogenesis and Progression of Prostate Cancer

Kim WT, Yun SJ, Kim WJ

MicroRNAs (miRNAs) are small noncoding RNAs that target mRNA to reduce gene and protein expression by repressing their targets' translation or inducing mRNA degradation. They play fundamental roles in various...
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Regulation of Adipocyte Differentiation via MicroRNAs

Son YH, Ka S, Kim AY, Kim JB

Adipocyte differentiation, termed adipogenesis, is a complicated process in which pluripotent mesenchymal stem cells differentiate into mature adipocytes. The process of adipocyte differentiation is tightly regulated by a number of...
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Clinical Aspect of MicroRNA in Lung Cancer

Jeong HC

MicroRNAs (miRNAs) are a class of small noncoding RNAs that modulate target gene activity, and are aberrantly expressed in most types of cancer as well in lung cancer. A miRNA...
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Role of MicroRNA in Visceral Pain

Zhang J, Banerjee B

  • KMID: 2381248
  • J Neurogastroenterol Motil.
  • 2015 Apr;21(2):159-171.
  • doi: 10.5056/jnm15027
The long-lasting nociceptive transmission under various visceral pain conditions involves transcriptional and/or translational alteration in neurotransmitter and receptor expression as well as modification of neuronal function, morphology and synaptic connections....
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MicroRNA Analysis in Normal Human Oral Keratinocytes and YD-38 Human Oral Cancer Cells

Kim HR, Park E, Cho KH, Kim DK

  • KMID: 1445159
  • Int J Oral Biol.
  • 2011 Dec;36(4):179-185.
MicroRNAs (miRNAs) are small non-coding RNAs that mediate gene expression at the post-transcriptional level by degrading or repressing targeted mRNAs. These molecules are about 21-25 nucleotides in length and exert...
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MicroRNAs in Human Diseases: From Lung, Liver and Kidney Diseases to Infectious Disease, Sickle Cell Disease and Endometrium Disease

Ha TY

MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs of about 22 nucleotides that have recently emerged as important regulators of gene expression at the posttranscriptional level. Recent...
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MicroRNA in the Diseased Pulmonary Vasculature: Implications for the Basic Scientist and Clinician

Jin RC, Min PK, Chan SY

Since the first descriptions of their active functions more than ten years ago, small non-coding RNA species termed microRNA (miRNA) have emerged as essential regulators in a broad range of...
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MicroRNAs in Human Diseases: From Autoimmune Diseases to Skin, Psychiatric and Neurodegenerative Diseases

Ha TY

MicroRNAs (miRNAs) are small noncoding RNA molecules that negatively regulate gene expression via degradation or translational repression of their target messenger RNAs (mRNAs). Recent studies have clearly demonstrated that miRNAs...
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Investigation of Dysregulation of Several MicroRNAs in Peripheral Blood of Schizophrenia Patients

Camkurt MA, Karababa F, Erdal ME, Bayazıt H, Kandemir S, Ay ME, Kandemir H, Ay OI, Çiçek E, Selek S, Taşdelen

OBJECTIVE: The prevalence of schizophrenia is 1%, and it is a debilitating disorder that often results in a shortened lifespan. Peripheral blood samples are good candidates to investigate because they...
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MicroRNA-374a Expression as a Prognostic Biomarker in Lung Adenocarcinoma

Kim Y, Sim J, Kim H, Bang SS, Jee S, Park S, Jang K

BACKGROUND: Lung cancer is the most common cause of cancer-related death, and adenocarcinoma is the most common histologic subtype. MicroRNA is a small non-coding RNA that inhibits multiple target gene...
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Regulation of microRNA-7-5p and LRP6 by Epstein-Barr Virus-Encoded RNAs in Burkitt's Lymphoma Cell Line Akata

Son JW, Choi HY, Lee HN, Seo MK, Lee SK

Epstein-Barr virus (EBV)-encoded small non-coding RNAs (EBERs) are abundantly expressed in various EBV-associated malignancies, and play critical roles in cell proliferation, tumorigenesis, and apoptosis resistance. However, the mechanism how EBERs...
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Differential MicroRNA Expression Profile of Human Embryonic Stem Cell-Derived Cardiac Lineage Cells

Kim YY, Min H, Kim H, Choi YM, Liu HC, Ku SY

MicroRNAs (miRNAs) are small non-coding RNA molecules that participate in transcriptional and post-transcriptional regulation of gene expression. miRNAs have numerous roles in cellular function including embryonic development. Human embryonic stem...
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Cell-Free microRNA-214 From Urine as a Biomarker for Non-Muscle-Invasive Bladder Cancer

Kim SM, Kang HW, Kim WT, Kim YJ, Yun SJ, Lee SC, Kim WJ

  • KMID: 2315962
  • Korean J Urol.
  • 2013 Nov;54(11):791-796.
PURPOSE: MicroRNAs are small noncoding RNAs and microRNA-214 (miR-214) has been associated with the inhibition of cancer cell growth, migration, and invasion. The aim of this study was to investigate...
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MicroRNAs in Autoimmune Sjögren's Syndrome

Cha S, Mona M, Lee KE, Kim DH, Han K

MicroRNAs (miRNAs), small non-coding RNAs, have been implicated in various diseases and cellular functions as microregulators of gene expression. Although the history of miRNA investigation in autoimmune Sjögren's syndrome (SjS)...
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MiR-1246 Promotes Metastasis and Invasion of A549 cells by Targeting GSK-3β‒Mediated Wnt/β-Catenin Pathway

Yang F, Xiong H, Duan L, Li Q, Li X, Zhou Y

PURPOSE: MicroRNAs (miRNAs) are a group of small non-coding RNAs involved in different cancers, including lung cancer. Here, we aim to investigate the expression profiles of circulating miRNAs and their...
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Dysregulated Expression Profiles of MicroRNAs of Experimentally Induced Cerebral Aneurysms in Rats

Lee HJ, Yi JS, Lee HJ, Lee IW, Park KC, Yang JH

OBJECTIVE: Cerebral aneurysm (CA) is an important acquired cerebrovascular disease that can cause catastrophic results. MicroRNAs (miRNAs) are small non-coding RNAs, playing essential roles in modulating basic physiologic and pathological...
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