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Proton therapy: the current status of the clinical evidences

Oh D

Proton therapy has the potential advantages of better conformal planning and higher biological effect than photon therapy (X-ray) for targeting tumor tissues. While the energy of a photon passes through...
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Radiation-induced Myositis after Proton Beam Therapy to Huge Hepatocellular Carcinoma

Kim J, Yoo GS, Sinn DH, Park HC, Koh KC

Proton beam therapy (PBT) is one of the advances in radiotherapy techniques, which enables dose escalation with lower probability of radiation-induced liver or gastrointestinal injuries. However, the chest wall proximal...
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Initial Experience of Patient-Specific QA for Wobbling and Line-Scanning Proton Therapy at Samsung Medical Center

Jo K, Ahn SH, Chung K, Cho S, Shin EH, Park S, Hong CS, Kim DH, Lee B, Lee W, Choi DH, Lim DH, Pyo HR, Han Y

PURPOSE: To report the initial experience of patient-specific quality assurance (pQA) for the wobbling and line-scanning proton therapy at Samsung Medical Center. MATERIALS AND METHODS: The pQA results of 89 wobbling...
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Current status of proton therapy techniques for lung cancer

Han Y

Proton beams have been used for cancer treatment for more than 28 years, and several technological advancements have been made to achieve improved clinical outcomes by delivering more accurate and...
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Therapeutic Proton Beam Range Measurement with EBT3 Film and Comparison with Tool for Particle Simulation

Lee N, Kim C, Song MH, Lee SB

PURPOSE: The advantages of ocular proton therapy are that it spares the optic nerve and delivers the minimal dose to normal surrounding tissues. In this study, it developed a solid...
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Stent-graft placement for treatment of massive hemobilia caused by porto-biliary fistula

Takahashi , Sato Y, Hara K, Okuno N, Dejima I, Murata S, Hasegawa T, Chatani S, Onaya H, Inaba Y

Proton beam therapy is a type of radiation therapy and a promising modality for cancer management because it involves few adverse effects and high therapeutic efficacy. However, there are reports...
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Clinical outcome of proton therapy for patients with chordomas

Youn SH, Cho KH, Kim JY, Ha B, Lim YK, Jeong JH, Lee SH, Yoo H, Gwak HS, Shin SH, Hong EK, Kim HK, Hong JB

PURPOSE: To investigate the clinical outcome of proton therapy (PT) in patients with chordoma. MATERIALS AND METHODS: Fifty-eight patients with chordoma treated with PT between June 2007 and December 2015 at...
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Radiation Therapy against Pediatric Malignant Central Nervous System Tumors : Embryonal Tumors and Proton Beam Therapy

Lim DH

Radiation therapy is highly effective for the management of pediatric malignant central nervous system (CNS) tumors including embryonal tumors. With the increment of long-term survivors from malignant CNS tumors, the...
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Clinical Outcomes of Proton Beam Therapy for Choroidal Melanoma at a Single Institute in Korea

Kim TW, Choi E, Park J, Shin DH, Jung SK, Seok S, Cho KH, Kim JY, Kim DY, Kim TH, Suh YK, Kim YJ, Moon SH

PURPOSE: This study retrospectively evaluated the clinical outcomes and complications of proton beam therapy (PBT) in a single institution in Korea and quantitatively analyzed the change in tumor volume after...
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Initial clinical outcomes of proton beam radiotherapy for hepatocellular carcinoma

Yu JI, Yoo GS, Cho S, Jung SH, Han Y, Park S, Lee B, Kang W, Sinn DH, Paik YH, Gwak GY, Choi MS, Lee JH, Koh KC, Paik SW, Park HC

PURPOSE: This study aimed to evaluate the initial outcomes of proton beam therapy (PBT) for hepatocellular carcinoma (HCC) in terms of tumor response and safety. MATERIALS AND METHODS: HCC patients who...
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A Case of Hepatocellular Carcinoma Treated by Proton Beam Therapy as 1st Choice

Oh J, Sinn DH, Seong G, Chung HG, Heo C, Yu J, Park HC

Although first-line treatment option for single, small sized hepatocellular carcinoma in patients with preserved liver function and good performance status is resection or ablation, sometimes these modalities cannot be applied...
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Radioprotective effects of delphinidin on normal human lung cells against proton beam exposure

Kim HM, Kim SH, Kang BS

BACKGROUND/OBJECTIVES: Exposure of the normal lung tissue around the cancerous tumor during radiotherapy causes serious side effects such as pneumonitis and pulmonary fibrosis. Radioprotectors used during cancer radiotherapy could protect...
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A Pilot Study of the Scanning Beam Quality Assurance Using Machine Log Files in Proton Beam Therapy

Chung K

The machine log files recorded by a scanning control unit in proton beam therapy system have been studied to be used as a quality assurance method of scanning beam deliveries....
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Development of a Real-Time Internal and External Marker Based Gating System for Proton Therapy

Cho J, Cheon W, Ahn S, Lee M, Park HC, Han Y

In respiratory-induced proton therapy, the accuracy of tracking system and beam controlling is more important than photon therapy. Therefore, a high accuracy motion tracking system that can track internal marker...
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The Effect of Anti-reflux Therapy on Patients Diagnosed with Minor Disorders of Peristalsis in High-resolution Manometry

Jeong J, Kim SE, Park MI, Park SJ, Moon W, Kim JH, Jung K, Choi YJ, Lee JY, Lee YD

BACKGROUND/AIMS: Minor disorders of peristalsis are esophageal motility disorders categorized by the Chicago Classification (CC), version 3.0, which was announced in 2014. This study evaluated the efficacy of anti-reflux therapy...
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Development of an Analytic Software Using Pencil Beam Scanning Proton Beam

Jeong S, Yoon M, Chung K, Han Y, Lim DH, Choi DH

We have developed an analytic software that can easily analyze the spot position and width of proton beam therapy nozzles in a periodic quality assurance. The developed software consists of...
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Correction of Prompt Gamma Distribution for Improving Accuracy of Beam Range Determination in Inhomogeneous Phantom

Park JH, Kim SH, Ku Y, Lee HS, Kim YS, Kim CH, Shin DH, Lee SB, Jeong JH

For effective patient treatment in proton therapy, it is therefore important to accurately measure the beam range. For measuring beam range, various researchers determine the beam range by measuring the...
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Dosimetric Impact of Ti Mesh on Proton Beam Therapy

Cho S, Goh Y, Kim C, Kim H, Jeong JH, Lim YK, Lee SB, Shin D

When a high density metallic implant is placed in the path of the proton beam, spatial heterogeneity can be caused due to artifacts in three dimensional (3D) computed tomography (CT)...
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Neurocognitive and Psychological Functioning of Children with an Intracranial Germ Cell Tumor

Park Y, Yu ES, Ha B, Park HJ, Kim JH, Kim JY

PURPOSE: This study was conducted to investigate the neurocognitive functioning of children with intracranial germ cell tumor (IGCT) prior to receiving proton beam therapy (PBT), and to identify differential characteristics...
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Secondary Neutron Dose Measurement for Proton Line Scanning Therapy

Lee C, Lee S, Chung K, Han Y, Chung YH, Kim JS

Proton therapy is increasingly being actively used in the treatment of cancer. In contrast to photons, protons have the potential advantage of delivering higher doses to the cancerous tissue and...
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