- GRA Proteins of Toxoplasma gondii: Maintenance of Host-Parasite Interactions across the Parasitophorous Vacuolar Membrane
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Nam HW
- KMID: 1734299
- Korean J Parasitol.
- 2009 Oct;47(Suppl):S29-S37.
- doi: 10.3347/kjp.2009.47.S.S29
The dense granule of Toxoplasma gondii is a secretory vesicular organelle of which the proteins participate in the modification of the parasitophorous vacuole (PV) and PV membrane for the maintenance... -
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- Interactions between secreted GRA proteins and host cell proteins across the paratitophorous vacuolar membrane in the parasitism of Toxoplasma gondii
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Ahn HJ, Kim S, Kim HE, Nam HW
- KMID: 1088762
- Korean J Parasitol.
- 2006 Dec;44(4):303-312.
- doi: 10.3347/kjp.2006.44.4.303
Interactions between GRA proteins of dense granules in Toxoplasma gondii and host cell proteins were analyzed by yeast two-hybrid technique. The cMyc-GRA fusion proteins expressed from pGBKT7 plasmid in Y187... -
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- Cross-Regulation of Innate and Adaptive Immunity: A New Perspective for the Pathogenesis of Inflammatory Bowel Disease
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Oh DY, Koh SJ
- KMID: 2155636
- Gut Liver.
- 2015 May;9(3):263-264.
- doi: 10.5009/gnl15123
No abstract available. -
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- The proteins of synaptic vesicle membranes are affected during ageing of rat brain
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Lee SR, Kim AR, Kim JS, Kim JB, Lee JY, Lee YL, Choe M, Park JB
- KMID: 1457533
- Exp Mol Med.
- 2001 Dec;33(4):220-225.
Low molecular weight GTP-binding proteins are molecular switches that are believed to play pivotal roles in cell growth, differentiation, cytoskeletal organization, and vesicular trafficking. Rab proteins are key players in... -
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- Autophagy Activity in Pulmonary Metastatic Tumor Tissues from Colorectal Cancer: A Pilot Study
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Kim YS, Shin JH, Bae MK, Lee CY, Kim DJ, Chung KY, Lee JG
- KMID: 2070194
- Yonsei Med J.
- 2014 Nov;55(6):1484-1488.
- doi: 10.3349/ymj.2014.55.6.1484
PURPOSE: Autophagy has been reported to be involved in treatment failure in tumor. We aimed to evaluate autophagy activity in tumor tissue and compare them between the recurrence and non-recurrence... -
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- G protein signaling in the parasite Entamoeba histolytica
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Bosch DE, Siderovski DP
- KMID: 2154234
- Exp Mol Med.
- 2013 Mar;45(3):e15.
The parasite Entamoeba histolytica causes amebic colitis and systemic amebiasis. Among the known amebic factors contributing to pathogenesis are signaling pathways involving heterotrimeric and Ras superfamily G proteins. Here, we... -
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- Cell Cycle Regulators as Prognostic Predictor of Colorectal Cancers
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Jang SJ
- KMID: 772708
- Korean J Gastroenterol.
- 2004 Dec;44(6):346-349.
No abstract available. -
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- Evaluation of Infective Property of Recombinant Prion Protein Amyloids in Cultured Cells Overexpressing Cellular Prion Protein
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Kim DH, Lee HM, Ryou C
- KMID: 2069947
- J Korean Med Sci.
- 2014 Dec;29(12):1604-1609.
- doi: 10.3346/jkms.2014.29.12.1604
Misfolded isoform of prion protein (PrP), termed scrapie PrP (PrP(Sc)), tends to aggregate into various fibril forms. Previously, we reported various conditions that affect aggregation of recombinant PrP into amyloids.... -
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- The pleckstrin homology domain of phospholipase D1 accelerates EGFR endocytosis by increasing the expression of the Rab5 effector, rabaptin-5
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Park MH, Choi KY, Min DS
- KMID: 2359887
- Exp Mol Med.
- 2015 Dec;47(12):e200.
- doi: 10.1038/emm.2015.101
Endocytosis is differentially regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) and phospholipase D (PLD). However, the relationship between HIF-1alpha and PLD in endocytosis is unknown. HIF-1alpha is degraded through the prolyl hydroxylase... -
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- The expressions of HSP70 and alphaB-crystallin in myocarditis associated with foot-and-mouth disease virus in lambs
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Gulbahar M, Kabak YB, Karayigit , Yarim M, Guvenc T, Parlak U
- KMID: 1067339
- J Vet Sci.
- 2011 Mar;12(1):65-73.
- doi: 10.4142/jvs.2011.12.1.65
This study describes the expression of heat shock protein70 (HSP70) and alpha-basic-crystallin (alpha-BC) and their association with apoptosis and some related adaptor proteins in the pathogenesis of foot-and-mouth disease virus... -
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- C/EBP binding activity to site F of the rat GLUT2 glucose transporter gene promoter is attenuated by c-Jun in vitro
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Kim JW, Ahn YH
- KMID: 755211
- Exp Mol Med.
- 2002 Nov;34(5):379-384.
The expression of the GLUT2 glucose transporter gene in liver is suppressed in cultured hepatoma cell lines and primary cultured hepatocytes. Earlier report showed that CCAAT/enhancer binding protein (C/EBP) regulates... -
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- Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma
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Joo M, Chi JG, Lee H
- KMID: 1781767
- J Korean Med Sci.
- 2005 Oct;20(5):829-834.
- doi: 10.3346/jkms.2005.20.5.829
The heat shock proteins (HSPs) are ubiquitous molecules induced in cells exposed to various stress conditions, including carcinogenesis. The HSP70 and HSP27 among HSPs are of special relevance in human... -
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- The Prognostic Impact of Heat Shock Proteins Expression in Patients with Esophageal Cancer: A Meta-Analysis
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Wang XW, Shi XH, Tong YS, Cao XF
- KMID: 2345875
- Yonsei Med J.
- 2015 Nov;56(6):1497-1502.
- doi: 10.3349/ymj.2015.56.6.1497
PURPOSE: Heat shock proteins (HSPs) are highly conserved molecular chaperones. There are various studies that assess the prognostic value of HSPs in patients with esophageal cancer, but the conclusion remains... -
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- Immunohistochemical localization of calcium binding proteins and some neurotransmitters in myenteric plexus of goat stomach
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Lee HS, Nam YS
- KMID: 1089476
- J Vet Sci.
- 2006 Dec;7(4):315-319.
- doi: 10.4142/jvs.2006.7.4.315
To understand the neurochemical properties of the gastric myenteric plexus of ruminants, the expression patterns of calbindin D-28k (CB), calretinin (CR), substance P (SP) and calcitonin gene-related peptide (CGRP) were... -
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- Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: implications for this complex in transcriptional regulation
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Lee SJ, Lee JK, Maeng YS, Kim YM, Kwon YG
- KMID: 1123466
- Exp Mol Med.
- 2009 Mar;41(3):189-200.
- doi: 10.3858/emm.2009.41.3.022
Protein phosphatase-1 (PP1) nuclear targeting subunit (PNUTS), also called PP1R10, p99, or CAT 53 was originally isolated as a mammalian nuclear PP1-binding protein. In this study, we performed yeast two-hybrid... -
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- B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-kappaB, AP-1, Nrf2, and osteopontin
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Kim MY, Song KS, Park GH, Chang SH, Kim HW, Park JH, Jin H, Eu KJ, Cho HS, Kang G, Kim YC, Cho MH
- KMID: 1120069
- J Vet Sci.
- 2004 Jun;5(2):131-137.
Toxic effects of ozone, 4-(N-methyl-N-nitrosamino)-1-(3- pyridyl)-1-butanone (NNK), and/or dibutyl phthalate (DBP) were examined through NF-kappaB, AP-1, Nrf2, and osteopontin (OPN) in lungs and livers of B6C3F1 mice. Electrophoretic mobility shift... -
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- O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes
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Park SY, Ryu J, Lee W
- KMID: 1056235
- Exp Mol Med.
- 2005 Jun;37(3):220-229.
It has been known that O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of proteins plays an important role in transcription, translation, nuclear transport and signal transduction. The increased flux of glucose through the... -
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- Detection of specific proteins in the aqueous humor in primary open-angle glaucoma
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Lee IS, Yu YS, Kim DM, Youn DH, Kim JQ
- KMID: 1735052
- Korean J Ophthalmol.
- 1990 Jun;4(1):1-4.
- doi: 10.3341/kjo.1990.4.1.1
To elucidate the mechanism of increased intraocular pressure in primary open-angle glaucoma (POAG), the protein profiles of aqueous humor obtained from POAG patients were compared with those of cataract patients... -
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- Clinicopathological Significance of Expression of Tspan-1, Jab1 and p27 in Human Hepatocellular Carcinoma
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Chen L, Yuan D, Wang GL, Wang Y, Wu YY, Zhu J
- KMID: 2157846
- J Korean Med Sci.
- 2010 Oct;25(10):1438-1442.
- doi: 10.3346/jkms.2010.25.10.1438
The aim of this study was to investigate the expression of Tspan-1, Jab1 and p27 in human hepatocellular carcinoma (HCC) and their clinicopathological significance. The expression of Tspan-1, Jab1 and... -
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- Immunohistochemical Analysis of ATRX, IDH1 and p53 in Glioblastoma and Their Correlations with Patient Survival
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Chaurasia , Park SH, Seo JW, Park CK
- KMID: 2373747
- J Korean Med Sci.
- 2016 Aug;31(8):1208-1214.
- doi: 10.3346/jkms.2016.31.8.1208
Glioblastoma (GBM) can be classified into molecular subgroups, on the basis of biomarker expression. Here, we classified our cohort of 163 adult GBMs into molecular subgroups according to the expression... -
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