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Biomarkers in Heart Failure: Focus on B-type Natriuretic Peptide

Yoo BS

  • KMID: 2263517
  • Korean J Med.
  • 2012 Jun;82(6):647-650.
Assays for B-type natriuretic peptide (BNP) or N-terminal pro-brain BNP (NTproBNP) BNP are useful diagnostic method for evaluation of patients with dyspnea. And, natriuretic peptide levels have important prognostic value...
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Theoretical Peptide Mass Distribution in the Non-Redundant Protein Database of the NCBI

Lim DJ, Oh HS, Kim HB

  • KMID: 2166213
  • Genomics Inform.
  • 2006 Jun;4(2):65-70.
Peptide mass mapping is the matching of experimentally generated peptides masses with the predicted masses of digested proteins contained in a database. To identify proteins by matching their constituent fragment...
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Cathelicidin LL-37: An Antimicrobial Peptide with a Role in Inflammatory Skin Disease

Reinholz M, Ruzicka T, Schauber J

  • KMID: 2434676
  • Ann Dermatol.
  • 2012 May;24(2):126-135.
Chronic inflammatory skin diseases such as atopic dermatitis, psoriasis or rosacea are very common. Although their exact pathogenesis is not completely understood all three diseases are characterized by dysregulation of...
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Isolation and Identification of the Antigen Recognized by Human Cytomegalovirus Specific Monoclonal Antibody SCMVM 34

Park CG, Kook YH, Cha CY, Hwang ES, Lim DG, Seoh JY, Park JW, Jong HS

  • KMID: 1540528
  • J Korean Soc Microbiol.
  • 1997 Jun;32(3):325-334.
Human cytomegalovirus (HCMV)-specific monoclonal antibody, SCMVM 34, recognizes early antigen confined to the nucleus of HCMV-infected cells. This study was performed to identify the antigen reactive to SCMVM 34 with...
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An antibody reactive to the Gly63-Lys68 epitope of NT-proBNP exhibits O-glycosylation-independent binding

Lee Y, Kim H, Chung J

The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP...
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Strategy of Dagnosis and Treatment for Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants

Lee JH

Patent ductus arteriosus (PDA) is a major morbidity in preterm infants, especially in extremely premature infants less than 28 weeks. Early diagnosis of hemodynamically significant PDA (hs-PDA) is not easy...
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The Role of Cardiac Biomarkers in the Diagnosis and Management of Patients Presenting with Suspected Acute Coronary Syndrome

Christenson E, Christenson RH

Myocardial infarction (MI) is the leading cause of death in the developed world. Biomarkers have an essential role in diagnosis, risk stratification, guiding management and clinical decision making in the...
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Characterization of Gp41 Polymorphisms in the Fusion Peptide Domain and T-20 (Enfuvirtide) Resistance-Associated Regions in Korean HIV-1 Isolates

Jang DH, Yoon CH, Choi BS, Chung YS, Kim HY, Chi SG, Kim SS

HIV-1 gp41 is an envelope protein that plays an essential role in virus entry. The mutation of gp41 affects HIV-1 entry and susceptibility to the fusion inhibitor T-20. Therefore, we...
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Pathologic Updates on Antibody Mediated Rejection in Renal Transplantation

Choi YJ

  • KMID: 2324076
  • J Korean Soc Transplant.
  • 2013 Jun;27(2):42-48.
Progress in the field of antibody mediated rejection (ABMR) in kidney transplantation has shown a rapid increase during the past two decades. New pathologic entities have emerged and replace old...
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Prognostic Implications of Procalcitonin and NT-ProBNP in Febrile Neutropenic Patients

Kim SY, Park YR, Choi KV, Lee YH

  • KMID: 2049250
  • Clin Pediatr Hematol Oncol.
  • 2010 Apr;17(1):9-18.
PURPOSE: Procalcitonin and N-terminal brain natriuretic propeptide (NT-proBNP) has been increasingly used as an inflammatory marker to identify patients with systemic infection and future cardiac events. The aim of this...
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Attenuated Allergenic Activity of Ovomucoid After Electrolysis

Kido J, Matsumoto

Ovomucoid (OMC) is the most prominent allergen causing hen's egg allergy, containing disulfide (S-S) bonds that may be responsible for its allergic action. As S-S bonds may be reduced during...
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Correlation between N-Terminal Pro-Brain Natriuretic Peptide and Doppler Echocardiographic Parameters of Left Ventricular Filling Pressure in Atrial Fibrillation

Kim WS, Park SH

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia with a population prevalence of about 1%. Natriuretic peptide level is elevated in patients with AF with diastolic dysfunction even...
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NT-proBNP as a useful tool in diagnosing incomplete Kawasaki disease

Lee DW, Kim YH, Hyun MC, Kwon TC, Lee SB

PURPOSE: To determine the efficacy of the N-terminal fragment of B-type natriuretic peptide (NT-proBNP) as a useful diagnostic method in children with incomplete Kawasaki disease (KD). METHODS: Ninety-six patients who were...
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Availability of Bedside N-terminal Pro-Brain Natriuretic Peptide Measurement as Prognostic Marker About Development of Major Adverse Cardiovascular Events in Patients of Acute Coronary Syndromes

Kim HJ, Park JS, Kim AJ, Roh JY, Kim KH, Shin DW

  • KMID: 2332078
  • J Korean Soc Emerg Med.
  • 2008 Feb;19(1):65-73.
PURPOSE: Natriuretic peptide levels are known to be associated with cardiac output and ventricular function. Recently it has been suggested that N-terminal pro-brain natriuretic peptide (NT-pro-BNP) is available as a...
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The Usefulness of NT-proBNP in Children with Chronic Kidney Disease

Hwang HH, Hong SJ, Cho MH, Ko CW

  • KMID: 1465939
  • Korean J Nephrol.
  • 2009 May;28(3):199-204.
PURPOSE:NT-proBNP (N-terminal pro-brain natriuretic peptide) is mainly secreted by cardiac myocytes of ventricle and can be used asdiagnosis and prognostic factor for heart failure. The aim of this study was...
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Cerebral Ischemic Stroke in an Infant with Acute Myocarditis: A Case Report

Lee GH, Kim YH

A 9-month-old infant presented with cough, tachypnea, and grunting was admitted. The patient was revealed to have cardiomegaly, high NT-proBNP, and severe left ventricular dilation and dysfunction; she was subsequently...
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The Effect of Peripheral CRF Peptide and Water Avoidance Stress on Colonic and Gastric Transit in Guinea Pigs

Hussain Z, Kim HW, Huh CW, Lee YJ, Park H

Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) diseases; however, there is frequent overlap between FD and IBS patients. Emerging evidence links the activation of corticotropin...
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Hyponatremia and Syndrome of Inappropriate Antidiuretic Hormone Secretion in Kawasaki Disease

Lim GW, Lee M, Kim HS, Hong YM, Sohn S

BACKGROUND AND OBJECTIVES: The pathogenesis of hyponatremia (serum sodium
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Relationship between Serum N-Terminal Pro-Brain Natriuretic Peptide Level and Left Ventricular Dysfunction and Extracellular Water in Continuous Ambulatory Peritoneal Dialysis Patients

Chung JH, Yun NR, Ahn CY, Lee WS, Kim HL

This study inquired the relationship between serum N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and left ventricular (LV) dysfunction and extracellular water in continuous ambulatory peritoneal dialysis (CAPD) patients. We conducted...
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Purification and characterization of recombinant murine endostatin in E. coli

You WK, So SH, Lee H, Park SY, Yoon MR, Chang SI, Kim HK, Joe YA, Hong YK, Chung SI

  • KMID: 1029927
  • Exp Mol Med.
  • 1999 Dec;31(4):197-202.
Endostatin, a carboxyl-terminal fragment of collagen XVIII is known as an anti-angiogenic agent, that specifically inhibits the proliferation of endothelial cell and the growth of several primary tumor....
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