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Acanthamoeba in Southeast Asia – Overview and Challenges

Bunsuwansakul C, Mahboob T, Hounkong K, Laohaprapanon S, Chitapornpan S, Jawjit S, Yasiri A, Barusrux S, Bunluepuech K, Sawangjaroen N, Salibay CC, Kaewjai C, de Lourdes Pereira M, Nissapatorn V

Acanthamoeba, one of free-living amoebae (FLA), remains a high risk of direct contact with this protozoan parasite which is ubiquitous in nature and man-made environment. This pathogenic FLA can cause...
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Efficacy of Topical Cyclosporine Nanoemulsion 0.05% Compared with Topical Cyclosporine Emulsion 0.05% and Diquafosol 3% in Dry Eye

Park CH, Kim MK, Kim EC, Kim JY, Kim TI, Kim HK, Song JS, Yoon KC, Lee DH, Lee HK, Chung TY, Choi CY, Kim HS

PURPOSE: To evaluate the efficacy and safety of cyclosporine nanoemulsion 0.05% compared to cyclosporine emulsion 0.05% and diquafosol sodium 3%. METHODS: This was a multicenter, randomized, evaluator-masked, active control, parallel, phase...
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Application of Nanotechnology in Targeting of Cancer Stem Cells: A Review

Asghari F, Khademi R, Ranjbar FE, Malekshahi ZV, Majidi RF

Cancer is increasingly apparent as a systems-level, network happening. The central tendency of malignant alteration can be described as a two-phase procedure, where an initial increase of network plasticity is...
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The Future Medical Science and Colorectal Surgeons

Kim YJ

Future medical technology breakthroughs will build from the incredible progress made in computers, biotechnology, and nanotechnology and from the information learned from the human genome. With such technology and information,...
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Current Status and Future Direction of Nanomedicine: Focus on Advanced Biological and Medical Applications

Kim EM, Jeong HJ

Nanotechnology is the engineering and manipulation of materials and devices with sizes in the nanometer range. Colloidal gold, iron oxide nanoparticles and quantum dot semiconductor nanocrystals are examples of nanoparticles,...
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NIRF Heptamethine Cyanine Dye Nanocomplexes for Multi Modal Theranosis of Tumors

Thomas RG, Jeong YY

Heptamethine cyanine dyes are categorized as a class of near infrared fluorescent (NIRF) dyes which have been discovered to have tumor targeting and accumulation capability. This unique feature of NIRF...
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MicroRNA Biomarkers in Neurodegenerative Diseases and Emerging Nano-Sensors Technology

Shah P, Cho SK, Thulstrup , Bjerrum MJ, Lee PH, Kang JH, Bhang YJ, Yang SW

MicroRNAs (miRNAs) are essential small RNA molecules (20–24 nt) that negatively regulate the expression of target genes at the post-transcriptional level. Due to their roles in a variety of biological...
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Application of photodynamic therapy in gastrointestinal disorders: an outdated or re-emerging technique?

Lee HH, Choi MG, Hasan T

Photodynamic therapy (PDT) is a promising therapeutic modality that involves the administration of a photosensitizer followed by local illumination with a specific wavelength of light in the presence of oxygen....
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Nanotechnology Biomimetic Cartilage Regenerative Scaffolds

Lim EH, Sardinha J, Myers S

Cartilage has a limited regenerative capacity. Faced with the clinical challenge of reconstruction of cartilage defects, the field of cartilage engineering has evolved. This article reviews current concepts and strategies...
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Nanoparticle-Based Vaccine Delivery for Cancer Immunotherapy

Park YM, Lee SJ, Kim YS, Lee MH, Cha GS, Jung ID, Kang TH, Han HD

Development of nano-sized carriers including nanoparticles, nanoemulsions or liposomes holds great potential for advanced delivery systems for cancer immunotherapy, as such nanostructures can be used to more effectively manipulate or...
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Toxicological Evaluations of Rare Earths and Their Health Impacts to Workers: A Literature Review

Rim KT, Koo KH, Park JS

  • KMID: 2317078
  • Saf Health Work.
  • 2013 Mar;4(1):12-26.
In concert with the development of new materials in the last decade, the need for toxicological studies of these materials has been increasing. These new materials include a group of...
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Risk Assessment Principle for Engineered Nanotechnology in Food and Drug

Hwang M, Lee EJ, Kweon SY, Park MS, Jeong JY, Um JH, Kim SA, Han BS, Lee KH, Yoon HJ

  • KMID: 1432242
  • Toxicol Res.
  • 2012 Jun;28(2):73-79.
While the ability to develop nanomaterials and incorporate them into products is advancing rapidly worldwide, understanding of the potential health safety effects of nanomaterials has proceeded at a much slower...
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Clinical Application of Nanotechnology

Baek SK

The limitations of current modalities for diagnosis and treatment of various diseases including cancer have led to look for the method with more sensitivity or specificity and lower toxicity. The...
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The Impact of Nanomaterials in Immune System

Jang J, Lim DH, Choi IH

As a nanotechnology has been actively applied to the overall areas of scientific fields, it is necessary to understand the characteristic features, physical behaviors and the potential effects of exposure...
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Evaluation of the Virus-elimination Efficacy of Nanofiltration (Viresolve NFP) for the Parvovirus B19 and Hepatitis A Virus

Oh DJ, Lee YL, Kang JW, Kwon SY, Cho NS, Kim IS

BACKGROUND: The safety of plasma derivatives has been reinforced since 1980s by variable pathogen inactivation or elimination techniques. Nucleic acid amplification test (NAT) for the source plasma has also been...
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Advances of Cancer Therapy by Nanotechnology

Wang X, Wang Y, Chen ZG, Shin DM

  • KMID: 2165990
  • Cancer Res Treat.
  • 2009 Mar;41(1):1-11.
Recent developments in nanotechnology offer researchers opportunities to significantly transform cancer therapeutics. This technology has enabled the manipulation of the biological and physicochemical properties of nanomaterials to facilitate more efficient...
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Nanomedicine: Drug Delivery Systems and Nanoparticle Targeting

Youn H, Kang KW, Chung JK, Lee DS

  • KMID: 2051945
  • Nucl Med Mol Imaging.
  • 2008 Oct;42(5):337-346.
Applications of nanotechnology in the medical field have provided the fundamentals of tremendous improvement in precise diagnosis and customized therapy. Recent advances in nanomedicine have led to establish a new...
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Development of Micro/Nano Devices for Cancer Diagnosis

Yoon DS, Kang JY, Kim TS

  • KMID: 782859
  • Korean J Gastroenterol.
  • 2007 May;49(5):280-286.
In order to rapidly detect and analyze the presence of a target ligand of interests in environmental or industrial fluids as well as biological samples, numerous test systems have been...
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Future Direction of Nanomedicine in Gastrointestinal Cancer

Song SY

  • KMID: 782858
  • Korean J Gastroenterol.
  • 2007 May;49(5):271-279.
Cancer is one of the leading causes of death in human, and among various cancers, gastrointestinal cancers occupy more than 55%. Gastric cancer is the first leading cause of cancer-related...
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In Vitro Antimicrobial Activities of NanoSilver-coated Gauze against Clinical Isolates

Uh Y, Hwang GY, Yoon KJ, Kim HY, Uh HS, Kwon OK

  • KMID: 2224736
  • Korean J Clin Microbiol.
  • 2007 Apr;10(1):37-43.
BACKGROUND: It is well-known that silver ions and silver compounds are broad-spectrum antimicrobial agents effective against gram-positive and gram-negative bacteria, and yeasts. Thus, silver ions, as an antibacterial agent, have...
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