Korean J Gastroenterol.
2007 May;49(5):280-286.
Development of Micro/Nano Devices for Cancer Diagnosis
- Affiliations
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- 1Microsystem Research Center, Intelligent Microsystem Center (21stC Frontier Research Program, MOCIE), Seoul, Korea. tskim@kist.re.k
- 2Korea Institute of Science and Technology, Seoul, Korea.
Abstract
- In order to rapidly detect and analyze the presence of a target ligand of interests in environmental or industrial fluids as well as biological samples, numerous test systems have been designed and developed, which have been based on the combination of a test reagent and absorbing paper or membrane. The main limitations of these conventional devices are the difficulty of quantitative or semi-quantitative detection and poor detection limit (around nanogram/ml range detection capability). In this paper, new approaches and research trends which use nano/MEMS (micro electro mechanical systems) technology is introduced, which has a concept of fast, precise, and massive diagnosis and analysis of target molecules using very small amount of samples.
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