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Encainide, a class Ic anti-arrhythmic agent, blocks voltage-dependent potassium channels in coronary artery smooth muscle cells

Li H, Zhou Y, Yang Y, Zha Y, Ye B, Mun SY, Zhuang W, Liang J, Park WS

Voltage-dependent K + (Kv) channels are widely expressed on vascular smooth muscle cells and regulate vascular tone. Here, we explored the inhibitory effect of encainide, a class Ic anti-arrhythmic agent,...
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A Case of Pleomorphic Adenoma of the External Auditory Canal

Kim YK, Park JH, Mun SY, Yoon YJ

  • KMID: 2275634
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jan;44(1):105-107.
Pleomorphic adenomas mostly occur in major salivary glands. Pleomorphic adenomas arising in the external auditory canal are very rare. The clinical features and natural history of patients with this tumor...
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A Case of Hyponatraemic Seizure Following Terlipressin Therapy for a Variceal Hemorrhage in a Patient with Liver Cirrhosis

Kim JH, Kim JK, Mun SY, Choi CJ, Park HM, Jeong YS, Kang JG

Terlipressin has splanchnic vasoconstrictive effects, and is generally used for the management of gastroesophageal variceal bleeding secondary to liver cirrhosis. Terlipressin is a synthetic arginine vasopressin (AVP) analog containing a...
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Effects of an Integrated Internet Addiction Prevention Program on Elementary Students' Self-regulation and Internet Addiction

Mun SY, Lee BS

PURPOSE: The purpose of this study was to develop an integrated internet addiction prevention program and test its effects on the self-regulation and internet addiction of elementary students who are...
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A Case of Therapeutic Percutaneous Embolization of Spontaneous Arteriovenous Fistulas with Pulsatile Tinnitus Involving the Branches of the Left External Carotid Artery

Lee SH, Yoon YJ, Mun SY, Choi SC

  • KMID: 2275917
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Apr;45(4):404-407.
Arteriovenous fistulas of head and neck, especially the external carotid artery are uncommon lesions usually of traumatic origin. They also may be spontaneous, inflammatory, or congenital origin. They maybe accompanied...
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Clinical Characteristics of Korean Rheumatoid Arthritis Patients with Indications for TNF-alpha Blocker

Son KM, Jung YO, Kim IJ, Kim BJ, Lee SY, Mun SY, Seo YI, Kim HA

OBJECTIVE: The aim of this study was to examine clinical characteristics of Korean rheumatoid arthritis (RA) patients with clinically indications for TNF-alpha blocker, and to compare their clinical parameters with...
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Inhibition of voltage-dependent K+ channels by antimuscarinic drug fesoterodine in coronary arterial smooth muscle cells

Park S, Kang M, Heo R, Mun SY, Park M, Han ET, Han JH, Chun W, Park H, Park WS

Fesoterodine, an antimuscarinic drug, is widely used to treat overactive bladder syndrome. However, there is little information about its effects on vascular K+ channels. In this study, voltage-dependent K+ (Kv)...
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Awareness of COPD in a High Risk Korean Population

Seo JY, Hwang YI, Mun SY, Kim JH, Kim JH, Park SH, Jang SH, Park YB, Shim JJ, Jung KS

PURPOSE: Increased awareness and understanding of chronic obstructive pulmonary disease (COPD) is an important aspect of disease management. The aim of this study was to explore COPD awareness among smokers...
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New in vitro multiple cardiac ion channel screening system for preclinical Torsades de Pointes risk prediction under the Comprehensive in vitro Proarrhythmia Assay concepta

An JR, Mun SY, Jung IK, Kim KS, Kwon CH, Choi SO, Park WS

Cardiotoxicity, particularly drug-induced Torsades de Pointes (TdP), is a concern in drug safety assessment. The recent establishment of human induced pluripotent stem cell-derived cardiomyocytes (human iPSC-CMs) has become an attractive...
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Inhibitory effects of the atypical antipsychotic, clozapine, on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells

Kang M, Heo R, Park S, Mun SY, Park M, Han ET, Han JH, Chun W, Ha KS, Park H, Jung WK, Choi IW, Park WS

To investigate the adverse effects of clozapine on cardiovascular ion channels, we examined the inhibitory effect of clozapine on voltage-dependent K+(Kv) channels in rabbit coronary arterial smooth muscle cells. Clozapine-induced...
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Awareness of chronic obstructive pulmonary disease in current smokers: a nationwide survey

Mun SY, Hwang YI, Kim JH, Park S, Jang SH, Seo JY, Kim JK, Park YB, Shim JJ, Jung KS

BACKGROUND/AIMS: Cigarette smoking is the most common risk factor for chronic obstructive pulmonary disease (COPD). However, few studies of the attitudes toward COPD of smokers, the group at risk of...
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