- Positive Selection of Transgenic CD4 T Cells in the Restricted Peptide Environment
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Lee DS, Lee WJ
- KMID: 2092706
- Korean J Anat.
- 1999 Oct;32(5):727-733.
In order to investigate the role of H2-M molecule on class II molecule other than H2-Ab we made H2-M deficient H2-E transgenic mice and to see the peptide diversity on... -
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- Transgenic Mice Models for Airway and Fibrotic Lung Diseases
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- KMID: 2299557
- Korean J Asthma Allergy Clin Immunol.
- 2009 Sep;29(3):151-156.
No abstract available. -
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- Animal Models of Alzheimer's Dementia
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Woo SI
- KMID: 2334613
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):149-152.
Transgenic mice models of Alzheimer's disease were produced by overexpressing APP(amyloid precursor protein) mutant and presenilin mutant genes using the promotors that induced neuronal expression. The neuropathologies, electrophysiological changes and... -
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- Pathologic Findings in the Liver of Hepatitis B Virus X Transgenic Mice
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Moon HB, Yu DY, So BJ, Kim HC, Han WC, Yun KJ, Yoo HN
- KMID: 2275538
- Korean J Pathol.
- 2003 Oct;37(5):342-350.
BACKGROUND: The aim of this study was to investigate the hepatic pathology of HBx transgenic mice. METHODS: The gross and histological examinations were done in 125 HBx transgenic mice and... -
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- New insight on immune tolerance from transgenic mouse models
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Lee MS
- KMID: 932124
- J Korean Med Sci.
- 1996 Feb;11(1):1-7.
- doi: 10.3346/jkms.1996.11.1.1
No abstract available. -
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- Effect of Glomerular Cyclooxygenase-2 Overexpression on Podocyte Injury Induced by Puromycin in Mice
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Jo YI
- KMID: 2254037
- Korean J Nephrol.
- 2007 Mar;26(2):127-136.
PURPOSE: The aim of this study is to investigate the effect of glomerular cyclooxygenase-2 (COX-2) overexpression on podocyte injury by puromycin aminonucleoside (PAN) in nephrin-driven COX-2 transgenic mice. METHODS: We administrated... -
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- Comparative Analysis of Gastrointestinal Microbiota Between Normal and Caudal-Related Homeobox 2 (Cdx2) Transgenic Mice
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Sakamoto H, Asahara T, Chonan O, Yuki N, Mutoh H, Hayashi S, Yamamoto H, Sugano K
- KMID: 1807375
- Intest Res.
- 2015 Jan;13(1):39-49.
- doi: 10.5217/ir.2015.13.1.39
BACKGROUND/AIMS: Caudal-related homeobox 2 (Cdx2) is expressed in the human intestinal metaplastic mucosa and induces intestinal metaplastic mucosa in the Cdx2 transgenic mouse stomach. Atrophic gastritis and intestinal metaplasia commonly... -
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- A Study on the Expression of Proliferating Cell Nuclear Antigen and Apoptosis of the Hepatocellular Carcinoma in Human and Hepatitis B Virus X Transgenic Mice
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Moon HB, Yu DY, Yoo HR, So BJ, Chae KM, Kim HC, Yun KJ, Han WC, Jo HJ, Kim BY
- KMID: 2275643
- Korean J Pathol.
- 2001 Apr;35(2):129-136.
BACKGROUND: This experiment was designed to study the cell kinetics of hepatocellular carcinoma (HCC) in both hepatitis B virus X (HBx) transgenic mice and humans. METHODS: The immunohistochemical stain of... -
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- Immunohistochemical Study on the Distribution of Glycogen Synthase Kinase (GSK) 3beta in the Central Nervous System of SOD1G93A Transgenic Mice
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Joo KM, Chung YH, Kim SS, Kim KY, Lee WB, Cha CI
- KMID: 1521308
- Korean J Phys Anthropol.
- 2007 Dec;20(4):355-362.
In the present study, we investigated influences of glycogen synthase kinase (GSK) 3beta on the development and/or progression of amyotrophic lateral sclerosis (ALS). We used transgenic mice expressing a human... -
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- Expression of hepatitis C virus nonstructural 4B in transgenic mice
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Wang AG, Moon HB, Kim JM, Hwang SB, Yu DY, Lee DS
- KMID: 1094149
- Exp Mol Med.
- 2006 Jun;38(3):241-246.
Hepatitis C virus (HCV) is a pathogen that is of great medical significance in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Although the HCV proteins have been intensively investigated... -
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- Region-specific changes in the immunoreactivity of Atg9A in the central nervous system of SOD1(G93A) transgenic mice
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Lee JC, Choe SY, Cha CI
- KMID: 1882580
- Anat Cell Biol.
- 2014 Jun;47(2):101-110.
- doi: 10.5115/acb.2014.47.2.101
Autophagy is a eukaryotic self-degradation system that plays a pivotal role in the maintenance of cellular homeostasis. Atg9 is the only transmembrane Atg protein required for autophagosome formation. Although the... -
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- Accelerated Induction of Dysplastic Lesion by TPA in HPV18 URR E6/E7 Gene Expressing Transgenic Mice
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Kwon Y, Park T, Park J, Um S, Yu J, Lee J, Namkoong S
- KMID: 2007127
- J Korean Cancer Assoc.
- 2001 Feb;33(1):56-63.
PURPOSE: The research of HPV has been severely hampered by the inability to propagate HPVs in culture, particularly those of the mucosotrophic types which produce few virions in vivo. In... -
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- Re-transmissibility of mouse-adapted ME7 scrapie strain to ovine PrP transgenic mice
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Babalola J, Kim JM, Lee YJ, Park JH, Choi HS, Choi YG, Choi EK, Kim YS
- KMID: 2454011
- J Vet Sci.
- 2019 Mar;20(2):e8.
- doi: 10.4142/jvs.2019.20.e8
Scrapie is a mammalian transmissible spongiform encephalopathy or prion disease that predominantly affects sheep and goats. Scrapie has been shown to overcome the species barrier via experimental infection of other... -
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- Ectopic Expression of Ephrin-A5 Under the EphA8 Promoter at the Anterior Region of the Superior Colliculus
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Noh H, Park S
- KMID: 2165319
- Exp Neurobiol.
- 2010 Jun;19(1):49-53.
- doi: 10.5607/en.2010.19.1.49
EphA/ephrin-A mediated signaling has emerged as a key mechanism regulating axon guidance and topographic mapping, particularly in the well-characterized visual system from the retina to the superior colliculus (SC). In... -
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- Eosinophil and IgE responses of IL-5 transgenic mice experimentally infected with Nippostrongylus brasiliensis
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Chai JY, Shin EH, Takatsu K, Matsumoto , Kojima S
- KMID: 1715271
- Korean J Parasitol.
- 1999 Jun;37(2):93-99.
- doi: 10.3347/kjp.1999.37.2.93
Eosinophil and IgE responses of interleukin (IL)-5 transgenic and normal C3H/HeN mice were studied after experimental infection with Nippostrongylus brasiliensis (Nb). Intestinal worms were recovered at day 5 post-infection... -
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- Model Development of Papillary Thyroid Carcinoma by BRAFV600E Transgenic Mice
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Lee JU, Joung KH, Jo YS, Shong M
- KMID: 2012969
- J Korean Thyroid Assoc.
- 2011 May;4(1):30-38.
BACKGROUND AND OBJECTIVES: The BRAFV600E mutation has been regarded as the leading cause of papillary thyroid cancer (PTC). However, the multi-step carcinogenic process induced by BRAFV600E has been remained to... -
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- Evaluation of Vascular Smooth Muscle Cell Lineages Derived from the Transgenic Mice Expressing Temperature-Sensitive Simian Virus 40 T Antigen Targeted to Smooth Muscle
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Huh NE
- KMID: 1938494
- Korean Circ J.
- 1999 May;29(5):507-516.
- doi: 10.4070/kcj.1999.29.5.507
BACKGROUND AND OBJECTIVES: As a part of efforts to evaluate effectiveness of aorta cell lineages derived from the transgenic mice in which expression of the temperature-sensitive SV40 large T antigen... -
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- Up-regulation of Human nm23-H2/NDP Kinase B in Early Phase of Regenerating Transgenic Mouse Hepatocyte
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Lee IH
- KMID: 2071852
- Korean J Phys Anthropol.
- 1999 Jun;12(1):169-174.
The kinetics and subcellular localization of nm23-M1 and -M2 was reported in in vivo regenerating mouse liver cells after partial hepatectomy (Lee et al. 1997a). On the human nm23-H2 transgenic... -
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- Cyclooxygenase 2 in Gastric Carcinoma Is Expressed in Doublecortin- and CaM Kinase-Like-1-Positive Tuft Cells
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Mutoh H, Sashikawa , Sakamoto H, Tateno T
- KMID: 2070061
- Gut Liver.
- 2014 Sep;8(5):508-518.
- doi: 10.5009/gnl13237
BACKGROUND/AIMS: Doublecortin and CaM kinase-like-1 (DCAMKL1) is a marker of stem cells expressed predominantly in the crypt base in the intestine. However, DCAMKL1-positive cells have been shown to be differentiated... -
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- Amelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol
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Jung YY, Lee YJ, Choi DY, Hong JT
- KMID: 2170641
- Biomol Ther.
- 2014 May;22(3):232-238.
Alzheimer's disease (AD) is the most common neurodegenerative disease without known ways to cure. A key neuropathologic manifestation of the disease is extracellular deposition of beta-amyloid peptide (Abeta). Specific mechanisms... -
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