- Biomarker for Ischemic Stroke Using Metabolome: A Clinician Perspective
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Sidorov E, Sanghera D, Vanamala J
- KMID: 2438648
- J Stroke.
- 2019 Jan;21(1):31-41.
- doi: 10.5853/jos.2018.03454
Finding ischemic stroke biomarker is highly desirable because it can improve diagnosis even before a patient arrives to the hospital. Metabolome is one of new technologies that help to find... -
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- Metabolomic Analysis Identifies Alterations of Amino Acid Metabolome Signatures in the Postmortem Brain of Alzheimer's Disease
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Kim YH, Shim HS, Kim KH, Lee J, Chung BC, Kowall NW, Ryu H, Lee J
- KMID: 2451073
- Exp Neurobiol.
- 2019 Jun;28(3):376-389.
- doi: 10.5607/en.2019.28.3.376
Despite significant advances in neuroscience research over the past several decades, the exact cause of AD has not yet fully understood. The metabolic hypothesis as well as the amyloid and... -
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- Understanding Metabolomics in Biomedical Research
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Kim SJ, Kim SH, Kim JH, Hwang S, Yoo HJ
- KMID: 2169686
- Endocrinol Metab.
- 2016 Mar;31(1):7-16.
- doi: 10.3803/EnM.2016.31.1.7
The term "omics" refers to any type of specific study that provides collective information on a biological system. Representative omics includes genomics, proteomics, and metabolomics, and new omics is constantly... -
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- Understanding of Cancer Cell Metabolism and Thyroid Cancer
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Kim WG, Kim WB
- KMID: 2171222
- Int J Thyroidol.
- 2015 Nov;8(2):147-152.
- doi: 10.11106/ijt.2015.8.2.147
Metabolic reprogramming of cancer cell is one of essential hallmarks of cancer. Otto Warburg first demonstrated that cancer cells utilized more glucose and enhanced glycolytic pathway in the presence of... -
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- Unmasking molecular profiles of bladder cancer
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Piao XM, Byun YJ, Kim WJ, Kim J
- KMID: 2404975
- Investig Clin Urol.
- 2018 Mar;59(2):72-82.
- doi: 10.4111/icu.2018.59.2.72
Precision medicine is designed to tailor treatments for individual patients by factoring in each person's specific biology and mechanism of disease. This paradigm shifted from a “one size fits allâ€... -
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- The exposome and the future of epidemiology: a vision and prospect
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Kim KN, Hong YC
- KMID: 2411241
- Environ Health Toxicol.
- 2017 ;32(1):e2017009.
- doi: 10.5620/eht.e2017009
It is widely accepted that a relatively small proportion of chronic disease can be explained by genetic factors alone. Although information about environmental exposure is important to comprehensively evaluate chronic... -
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- Changes in Metabolic Profile Over Time: Impact on the Risk of Diabetes
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Cho Y, Lee SH
- KMID: 2455664
- Diabetes Metab J.
- 2019 Aug;43(4):407-409.
- doi: 10.4093/dmj.2019.0141
No abstract available. -
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- Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry
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Kim JS, Kim AH, Jang C, Jang IJ, Kim KB, Cho JY, Hwang HY
- KMID: 2442638
- J Korean Med Sci.
- 2019 Apr;34(13):e104.
- doi: 10.3346/jkms.2019.34.e104
BACKGROUND: The left internal thoracic artery (LITA) has been used as the first conduit of choice in coronary artery bypass grafting (CABG) because of excellent long-term patency and outcomes. However,... -
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- XPERNATO-TOX: an Integrated Toxicogenomics Knowledgebase
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Woo JH, Kim HE, Kong G, Kim JH
- KMID: 2166193
- Genomics Inform.
- 2006 Mar;4(1):40-44.
Toxicogenomics combines transcriptome, proteome and metabolome profiling with conventional toxicology to investigate the interaction between biological molecules and toxicant or environmental stress in disease caution. Toxicogenomics faces the problems of... -
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- The relationship between polymorphism of glucose transporter gene and the metabolic profiles such as glucose utilization and insulin secretory capacity in the offsprings of non-insulin dependent diabetic patients
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Lee HC, Lee YS, Park SW, Chung YS, Lim SK, Kim KR, Huh KB, Kim TY, Rhim JS
- KMID: 1698267
- Korean J Med.
- 1993 Jul;45(1):12-24.
No abstract available. -
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- Identification of Hypoxanthine and Phosphoenolpyruvic Acid as Serum Markers of Chemoradiotherapy Response in Locally Advanced Rectal Cancer
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Kim K, Yeo SG, Yoo BC
- KMID: 2380393
- Cancer Res Treat.
- 2015 Jan;47(1):78-89.
- doi: 10.4143/crt.2013.127
PURPOSE: Patients show variable responses to chemoradiotherapy (CRT), which is generally administered before surgery for locally advanced rectal cancer (LARC). The aim of this study was to identify molecular markers... -
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- Metabolic Profiling of Plasma from Pancreatic Cancer Patients in Korea
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Gwon MR, Yoon YR, Seol YM, Choi YJ, Kim DU, Choe S, Lee SH, Hwang SY, Kim H
- KMID: 2448662
- Korean J Pancreas Biliary Tract.
- 2019 Apr;24(2):61-67.
- doi: 10.15279/kpba.2019.24.2.61
BACKGROUND/AIMS: Pancreatic cancer (PC) patients have poor prognoses because this cancer is typically diagnosed at an advanced stage and the therapeutic options are limited. We examined the potential of metabolic... -
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- Pharmacometabolomics: Current Applications and Future Perspectives
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Kim HJ, Yoon YR
- KMID: 2317851
- Transl Clin Pharmacol.
- 2014 Jun;22(1):8-10.
Metabolomics, a novel "omics" platform, is a powerful tool for the discovery of clinically useful biomarkers and biochemical processes to improve diagnosis and therapy. Through the use of advanced analytical... -
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- Direct Analysis in Real Time Mass Spectrometry (DART-MS) Analysis of Skin Metabolome Changes in the Ultraviolet B-Induced Mice
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Park HM, Kim HJ, Jang YP, Kim SY
- KMID: 2170665
- Biomol Ther.
- 2013 Nov;21(6):470-475.
Ultraviolet (UV) radiation is a major environmental factor that leads to acute and chronic reactions in the human skin. UV exposure induces wrinkle formation, DNA damage, and generation of reactive... -
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- Ectopic Fat Assessment Focusing on Cardiometabolic and Renal Risk
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Lim S
- KMID: 2169344
- Endocrinol Metab.
- 2014 Mar;29(1):1-4.
- doi: 10.3803/EnM.2014.29.1.1
It is well known that people with high levels of body fat are at higher risk for developing diabetes mellitus, kidney disease, and cardiovascular disorders. Since individuals who are slightly... -
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- Adiponectin and Ghrelin Polymorphism in Korean Women with Polycystic Ovary Syndrome
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Lee H, Byun EK, Park HR, Oh JY, Hong Y, Sung YA, Chung H
- KMID: 1511989
- J Korean Endocr Soc.
- 2006 Oct;21(5):394-401.
- doi: 10.3803/jkes.2008.21.5.394
BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and chronic anovulation, and this is a common disorder in premenopausal women. However, the pathogenesis is still uncertain. There has been... -
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- Investigation of the Growth Rate Change in Recombinant BCG which was cloned Mycobacterium tuberculosis Adenylate Kinase Mutation Gene or Human Muscle-type Adenylate Kinase Synthetic Gene
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Lee SH, Kim HJ, Park YK, Bai GH
- KMID: 2318818
- Tuberc Respir Dis.
- 2006 Feb;60(2):187-193.
BACKGROUND: Normal cell proliferation and viability is strongly depends on the availability of metabolic energy and the maintenance of the appropriate adenylate-nucleotide pools. Hypothetically, changes in adenylate kinase (AK) expression... -
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- Effects of Resistance Exercise on Bone Health
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Hong AR, Kim SW
- KMID: 2427438
- Endocrinol Metab.
- 2018 Dec;33(4):435-444.
- doi: 10.3803/EnM.2018.33.4.435
The prevalence of chronic diseases including osteoporosis and sarcopenia increases as the population ages. Osteoporosis and sarcopenia are commonly associated with genetics, mechanical factors, and hormonal factors and primarily associated... -
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- Metabolomics Insights Into Pathophysiological Mechanisms of Interstitial Cystitis
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Fiehn O, Kim J
- KMID: 2232937
- Int Neurourol J.
- 2014 Sep;18(3):106-114.
- doi: 10.5213/inj.2014.18.3.106
Interstitial cystitis (IC), also known as painful bladder syndrome or bladder pain syndrome, is a chronic lower urinary tract syndrome characterized by pelvic pain, urinary urgency, and increased urinary frequency... -
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- A Comparative Study Assessing Metabolic Profile and Diet Quality in College Women According to Their Mother's Diabetes Mellitus
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Cho KO
- KMID: 2332234
- J Korean Diet Assoc.
- 2009 Feb;15(1):1-9.
The objective of this study was to assess the metabolic profiles and diet quality in college women by their mother's diabetes mellitus status. The study subjects, all college women, were... -
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