- Immunogenicity of a new, inactivated canine adenovirus type 2 vaccine for dogs
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Yang DK, Kim HH, Yoo JY, Ji M, Han BH, Oh S, Hyun BH
- KMID: 2470836
- Clin Exp Vaccine Res.
- 2020 Jan;9(1):40-47.
- doi: 10.7774/cevr.2020.9.1.40
PURPOSE: We constructed a new canine adenovirus type 2 (CAV-2) vaccine candidate using the recently isolated Korean CAV-2 strain; we termed the vaccine APQA1701-40P and evaluated its safety and immunogenicity... -
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- Recharacterization of the Canine Adenovirus Type 1 Vaccine Strain based on the Biological and Molecular Properties
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Yang DK, Kim HH, Lee EJ, Yoo JY, Yoon SS, Park J, Kim CH, Kim HR
- KMID: 2468032
- J Bacteriol Virol.
- 2019 Sep;49(3):124-132.
- doi: 10.4167/jbv.2019.49.3.124
Canine adenovirus type 1 (CAV-1) infection results in hepatitis in dogs. In this study, we investigated the biologic and genetic characteristics of the CAV-1 vaccine strain (CAV1V) to improve quality... -
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- Isolation and identification of canine adenovirus type 2 from a naturally infected dog in Korea
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Yang DK, Kim HH, Yoon SS, Lee H, Cho IS
- KMID: 2437692
- Korean J Vet Res.
- 2018 Dec;58(4):177-182.
- doi: 10.14405/kjvr.2018.58.4.177
Canine adenovirus type 2 (CAV-2) infection results in significant respiratory illness in dogs. Isolating and culturing CAV-2 allows for investigations into its pathogenesis and the development of vaccines and diagnostic... -
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- Optimized clade 2.3.2.1c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza
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Jang JW, Lee CY, Kim IH, Choi JG, Lee YJ, Yuk SS, Lee JH, Song CS, Kim JH, Kwon HJ
- KMID: 2412554
- J Vet Sci.
- 2017 Aug;18(S1):299-306.
- doi: 10.4142/jvs.2017.18.S1.299
A/Puerto Rico/8/34 (PR8)-derived recombinant viruses have been used for seasonal flu vaccines; however, they are insufficient for vaccines against some human-fatal H5N1 highly pathogenic avian influenza (HPAI) viruses (HPAIV) due... -
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- Detection of Autoantibodies against Aquaporin-1 in the Sera of Patients with Primary Sjögren's Syndrome
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Alam J, Choi YS, Koh JH, Kwok SK, Park SH, Song YW, Park K, Choi Y
- KMID: 2376867
- Immune Netw.
- 2017 Apr;17(2):103-109.
- doi: 10.4110/in.2017.17.2.103
The pathophysiology of glandular dysfunction in Sjögren's syndrome (SS) has not been fully elucidated. Previously, we reported the presence of autoantibodies to AQP-5 in patients with SS, which was associated... -
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- Establishment of canine kidney cell line for canine distemper virus replication
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Jeon KL, Hwang KK
- KMID: 2169005
- J Biomed Res.
- 2015 Mar;16(1):6-12.
- doi: 10.12729/jbr.2015.16.1.006
Kidney cells of canine embryos were separated into single cells using collagenase and dispase. Primary culture was conducted using these cells. To remove fibroblasts, these cells were treated with edetate... -
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- Neuraminidase Inhibitors from the Fermentation Broth of Phellinus linteus
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Hwang BS, Lee MS, Lee SW, Lee IK, Seo GS, Choi HJ, Yun BS
- KMID: 2312744
- Mycobiology.
- 2014 Jun;42(2):189-192.
During a search for neuraminidase inhibitors derived from medicinal fungi, we found that the fermentation broth of Phellinus linteus exhibited potent neuraminidase inhibitory activity. Through bioassay-guided fractionation, two active compounds... -
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- Translational Read-Through of a Nonsense Mutation Causing Bartter Syndrome
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Cho HY, Lee BH, Cheong HI
- KMID: 2158027
- J Korean Med Sci.
- 2013 Jun;28(6):821-826.
- doi: 10.3346/jkms.2013.28.6.821
Bartter syndrome (BS) is classified into 5 genotypes according to underlying mutant genes and BS III is caused by loss-of-function mutations in the CLCNKB gene encoding for basolateral ClC-Kb. BS... -
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- Recombinant influenza viruses as delivery vectors for hepatis B virus epitopes
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Song JM, Lee KH, Seong BL
- KMID: 2278791
- Clin Exp Vaccine Res.
- 2012 Jul;1(1):77-82.
- doi: 10.7774/cevr.2012.1.1.77
PURPOSE: Neuraminidase (NA) of influenza virus contains stalk region that shows a great deal of variability in both amino acid sequence and length. In this paper, we investigated generation of... -
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- Molecular Approach for Distal Renal Tubular Acidosis Associated AE1 Mutations
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Vasuvattakul S
- KMID: 1462999
- Electrolyte Blood Press.
- 2010 Jun;8(1):25-31.
- doi: 10.5049/EBP.2010.8.1.25
The molecular approaches to distal renal tubular acidosis (dRTA) associated AE1 mutations lead us to understand the genetic and pathophysiological aspects of the acidification defects. An unanticipated high value of... -
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- P2 Receptor-mediated Inhibition of Vasopressin-stimulated Fluid Transport and cAMP Responses in AQP2-transfected MDCK Cells
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Kim YH, Choi YJ, Bae HR, Woo JS
- KMID: 2285365
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):9-14.
- doi: 10.4196/kjpp.2009.13.1.9
We cultured canine kidney (MDCK) cells stably expressing aquaporin-2 (AQP2) on collagen-coated permeable membrane filters and examined the effect of extracellular ATP on arginine vasopressin (AVP)-stimulated fluid transport and cAMP... -
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- Changes of Tight Junction and Epithelial Cells after Treatment of Cadmium
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Lee SJ, Kim KY, Kim DJ, Chung YH, Kim SS, Lee WB, Cho DY, Sohn DS
- KMID: 1512957
- Korean J Phys Anthropol.
- 2007 Mar;20(1):69-82.
Cadmium (Cd) affects cell proliferation, differentiation, apoptosis and other cellular activities and can cause numerous molecular lesions that would be relevant to carcinogenesis. The mechanism of adverse effects of Cd... -
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- Role of Reactive Oxygen Species and Mitogen-activated Protein Kinases in 2, 3, 7, 8-tetrachlorodibinzo-p-dioxin-induced Fibronectin Secretion by MDCK Cells
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Yu MR, Ha H
- KMID: 2254244
- Korean J Nephrol.
- 2005 May;24(3):350-357.
BACKGROUND: 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD: dioxin) is a potent environmental toxicant that alters various cell function. Both reactive oxygen species (ROS) and mitogen-activated protein kinases (MAPK) mediate dioxin-induced cytotoxicity.... -
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- Viral Patterns and Clincal Analysis of Acute Respiratory Tract Infections of Children in Korea(September, 1998~August, 2002)
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Lee SJ, Park EY, Oh PS, Lee KH, Kim KN, Lee KM
- KMID: 2440105
- Korean J Pediatr Infect Dis.
- 2003 May;10(1):102-113.
- doi: 10.14776/kjpid.2003.10.1.102
PURPOSE: Acute respiratory tract infections are the most common illnesses in children. The great majority of these infections involving lower respiratory tracts infections(LRTI) are caused by respiratory viruses such as... -
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- Effects of 2,3,7,8-tetrachlorodibenzo- p-dioxin(TCDD) on Glomerular Mesangial and Tubular Epithelial Cell Activation
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Kim EN, Yu MR, Lim HJ, Hwang EW, Ha HJ, Lee HB
- KMID: 2254450
- Korean J Nephrol.
- 2002 Jan;21(1):12-19.
BACKGROUND: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a prototype compound of polyhalogenated aromatic hydrocarbons, produces diverse biologic effects. Although nephrotoxicity of aromatic hydrocarbons such as benzo[a]pyrene(BP) is well known, little is known about the... -
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- Epidemiology of Influenza Virus over 8 Years (1990~1998) in Seoul, Korea
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Nah SY, Park SE, Park JY, Lee HJ
- KMID: 2248232
- Korean J Infect Dis.
- 1999 Jun;31(3):210-216.
BACKGROUND: Influenza virus is well known to cause recurrent epidemics almost every winter. However, information regarding the epidemiologic pattern of influenza virus in Korea is limited. In this study, the... -
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- Effect of Oxalate on the Growth of Distal Renal Tubular Epithelial Cells
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Cho KS, Kim HH, Kim SW
- KMID: 2289978
- Korean J Urol.
- 1998 Sep;39(9):827-831.
PURPOSE: We tried to evaluate the effect of oxalate on the growth of distal renal tubular epithelial cells MATERIALS AND METHODS: Madin-Darby canine kidney(MDCK) cell line, derived from canine distal... -
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- Epidemiologic and Clinical Feature of Acute Lower Respiratory Tract Infections by Respiratory Syncytial Virus and Parainfluenza Virus in Children
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Lee JJ, Park HS, Kim MR, Lee HR, Kim DH, Park CY, Chung WK, Lee KM
- KMID: 2335277
- J Korean Pediatr Soc.
- 1997 Aug;40(8):1071-1080.
PURPOSE: This is to analyze epidemic and clinical features of acute respiratory tract infections (ALRTI) by respiratory syncytial virus (RSV) and parainfluenza virus (PIV), which are considered to be the... -
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