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The Clinical Efficacy of Levofloxacin(CRAVIT(R)) in the Treatment of Cutaneous Infection

Kang HJ, Kim HJ, Seo SL, Kim YS, Lee MA, Hahm JH

BACKGROUND: Levofloxacin, an oral fluroquinolone antibacterial agent, is the optical S-(-) isomer of ofloxacin. In vitro it is generally twice as potent as ofloxacin and active against most aerobic gram...
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Clinical Efficacy and Safety of Intravenous levofloxacin in Patients of Abdominal Operati

Chae YS, Choi SJ, Lee JH, Kim KS, Lee WJ, Kim BR

  • KMID: 2083195
  • Korean J Hepatobiliary Pancreat Surg.
  • 2001 Jul;5(1):169-173.
BACKGROUND/AIMS: For the investigation of the efficacy and safety of intravenous levofloxacin, The clinical study was carrried out in 30 patients with abdominal operation, especially in hepatobiliary and pancreatic division. METHODS:...
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Levofloxacin-induced Fixed Drug Eruption: A Case Report

Han SS, Oh EH, Kwon HI, Ko JY, Ro YS, Kim JE

  • KMID: 2391167
  • Korean J Dermatol.
  • 2017 Aug;55(7):445-448.
Fixed drug eruptions (FDEs) are characterized by the presence of site-specific recurrence of a solitary or multiple, well-circumscribed, erythematous macules or patches that recur with each exposure to a particular...
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Clostridium difficile Colitis after Topical Ophthalmic Use of Levofloxacin

Lee JW, Woo SY, Park SJ, Hong SH, Lee SY, Woo SM

Clostridium difficile colitis (CDC) has been associated with virtually all available antibiotics. It is well known that administration of drugs by the ocular route can result in systemic absorption with...
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The Efficacy of Oral Levofloxacin in the Treatment of Patient with Chronic Prostatitis

Oh CS, Cheon SH, Park RJ, Lee MS

  • KMID: 2170146
  • Infect Chemother.
  • 2005 Apr;37(2):99-103.
PURPOSE: Antibiotic is widely used in the treatment of chronic prostatitis. In this study, we evaluated the clinical efficacy and safety of levofloxacin (Cravit(R)) in the treatment of patients with...
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In-Vitro Activity of Tosufloxacin Compared with Levofloxacin and Ofloxacin against Uropathogens, Isolated from Acute Uncomplicated Cystitis in Female Outpatients

Lee SJ, Lee KS, Jeong SJ, Lee SE, Cho YH

  • KMID: 1528884
  • Infect Chemother.
  • 2007 Aug;39(4):202-207.
BACKGROUND: Tosufloxacin is one of the fluoroquinolones with higher antibacterial activity against many organisms than other fluoroquinolones developed previously. However, the antimicrobial susceptibilities of tosufloxacin against uropathogens are not well...
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The Effect of Levofloxacin on the Survival of Ovarian Cancer Cells with or Without Carboplatin Under Hypoxic Condition

Hong SY, Park JH, Kim EJ, Lee JW, Koh SB, Lee TS

  • KMID: 2272123
  • Korean J Obstet Gynecol.
  • 2003 Aug;46(8):1517-1524.
In solid tumor, there is a hypoxic region where oxygen supply is insufficient. In this study, we found that one of the quinolone antibiotics, levofloxacin, made a human ovarian cancer...
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Clinical Factors Associated with Acquisition of Resistance to Levofloxacin in Stenotrophomonas maltophilia

Baek JH, Kim CO, Jeong SJ, Ku NS, Han SH, Choi JY, Yong D, Song YG, Lee K, Kim JM

PURPOSE: Fluoroquinolones, rapidly gaining prominence in treatment of Stenotrophomonas maltophilia (SMP), are noted for their potency and tolerability. However, SMP may rapidly acquire resistance to fluoroquinolones. We evaluated associations of...
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A bioequivalence study of two levofloxacin tablets in healthy male subjects

Chung I, Yoon S, Yi S, Kim BH, Yim SV, Jang IJ, Lee H

Levofloxacin is a bactericidal broad spectrum antibiotic against Gram-positive and Gram-negative pathogens. A randomized, two-treatment, two-period, two-way crossover study was conducted to evaluate the bioequivalence of Lectacin 250 mg tablet,...
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Efficacy of Combination Therapy for Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Prospective Study

Mo KI, Lee KS, Kim DG

PURPOSE: The National Institute of Health (NIH) category III chronic nonbacterial prostatitis/chronic pelvic pain syndromes (CPPS) are commonly seen disorders; however, there has been no consensus on how to manage...
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Eradication Rate by Duration of Third-line Rescue Therapy with Levofloxacin after Helicobacter pylori Treatment Failure in Clinical Practice

Noh HM, Hong SJ, Han JP, Park KW, Lee YN, Lee TH, Ko BM, Lee JS, Lee MS

BACKGROUND/AIMS: This study evaluated the eradication rate of levofloxacin-containing rescue therapy by treatment duration in patients in whom previous first- and second-line treatment failed. METHODS: Fifty-five patients with persistent Helicobacter pylori...
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Comparison of Penetration Capability of Levofloxacin and Ciprofloxacin into Prostatic Tissue

Park HY, Jeong TY, Yang JJ, Yoo SH, Kim SJ, Shinm KY, Lee TY, Woo YN

  • KMID: 2290269
  • Korean J Urol.
  • 1998 Dec;39(12):1176-1179.
PURPOSE: To evaluate the penetration capability of Levofloxacin and Ciprofloxacin into prostatic tissue, we analysed the concentration of each drug in serum and prostatic tissue simultaneously after oral administration. MATERIALS...
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Pharmacokinetic comparison of two levofloxacin 100-mg tablet formulations and determination of time point appropriately reflecting its area under the curve

Park KR, Jang K, Lee S, Yu KS, Kim BH, Yim SV

Levofloxacin is a broad-spectrum antibiotic with activity against gram-positive and -negative bacteria. This study compared the pharmacokinetics (PK) and evaluated the bioequivalence of two levofloxacin 100-mg tablet formulations. An open,...
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Concentrations of Ofloxacin, Levofloxacin and Ciprofloxacin in Human Aqueous Humor after Topical Administration

Han YS, Nam DH, Shyn KH, Park JY, Kim KA, Kim SW, Song JS

  • KMID: 2126258
  • J Korean Ophthalmol Soc.
  • 2005 Apr;46(4):605-609.
PURPOSE: To evaluate the concentrations of commercially available ofloxacin 0.3%, levofloxacin 0.5%, and ciprofloxacin 0.3% topical ophthalmic solutions in human aqueous humor. METHODS: Patients scheduled to undergo phacoemulsification and posterior...
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A Case of Pulmonary Tuberculosis with Delayed Diagnosis Due to the Temporary Clinical Improvement After Use of Levofloxacin and Amikacin Under the Impression of Community Acquired Pneumonia

Lee HS, Kang YA, Oh JY, Lee JH, Yoo CG, Lee CT, Kim YW, Han SK, Shim YS, Yim JJ

  • KMID: 2318435
  • Tuberc Respir Dis.
  • 2003 Oct;55(4):395-401.
Fluoroquinolone is one of the first-line antibiotics recommended for treating community-acquired pneumonia. However, using fluroquinolones for presumptive community-acquired pneumonia can delay the diagnosis and the treatment of pulmonary tuberculosis because...
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Association between the Levofloxacin Plasma Concentration and Neurological Adverse Events in an Elderly Patient

Kang G, Min SH, Kim JK, Kang KW

No abstract available.
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Two Cases of Green Nail Syndrome

Kim BJ, Byun HJ, Lee DH, Cho S, Kim MN, Ro BI, Lee YW, Choe YB, Ahn KJ

  • KMID: 1513604
  • Korean J Med Mycol.
  • 2006 Sep;11(3):163-165.
Green nail syndrome is characterized by greenish discoloration of the nail. It is caused by Pseudomas aeruginosa which is an aerobic gram-negative rod found in moist environment. The most common...
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Management of Antibiotic-Resistant Helicobacter pylori Infection: Perspectives from Vietnam

Van Khien , Thang DM, Hai TM, Duat NQ, Khanh PH, Ha DT, Binh TT, Dung HD, Trang TT, Yamaoka Y

Antibiotic resistance is the most important factor leading to the failure of eradication regimens. This review focuses on the prevalence of Helicobacter pylori primary and secondary resistance to clarithromycin, metronidazole,...
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A Case of Drug Eruption Caused by Quinolones

Kim KH, Lew W

  • KMID: 2250967
  • Korean J Dermatol.
  • 2001 Dec;39(12):1440-1442.
The drug eruptions caused by quinolones are rarely reported. The patient took norfloxacin for several days prior to admission and was admitted due to systemic erythematous maculopapular eruptions. For the...
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Epithelial Wound Healing after Cataract Surgery Comparing Two Different Topical Fluoroquinolones

Han KE, Chung WS, Kim TI, Kim S, Kim T, Kim EK

PURPOSE: To compare the epithelial wound healing response of two preservative-free fluoroquinolones, moxifloxacin and levofloxacin, in patients who underwent cataract surgery. MATERIALS AND METHODS: In this prospective, evaluator-masked, randomized clinical trial,...
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