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A phase 1/2a, dose-escalation, safety and preliminary efficacy study of oral therapeutic vaccine in subjects with cervical intraepithelial neoplasia 3

Park YC, Ouh YT, Sung MH, Park HG, Kim TJ, Cho CH, Park JS, Lee JK

OBJECTIVE: Persistent infection of HPV increases the chance of carcinoma in situ of cervix through stages of cervical intraepithelial neoplasia (CIN) 1, 2, and 3, and finally progresses into cervical...
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Analysis of Correlation among Oral Environment, Oral Myofunction, and Oral Microorganisms

Kim SH

BACKGROUND: Factors affecting oral function include tooth number, oral muscle strength, and oral diseases. This study aimed to investigate the relationship among oral environment, muscle, and microbiology. METHODS: Fifty-six elderly individuals...
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Differential Effects of Lactobacillus casei Strain Shirota on Patients With Constipation Regarding Stool Consistency in China

Chen S, Ou Y, Zhao L, Li Y, Qiao Z, Hao Y, Ren F

  • KMID: 2433508
  • J Neurogastroenterol Motil.
  • 2019 Jan;25(1):148-158.
  • doi: 10.5056/jnm17085
BACKGROUND/AIMS: Probiotics are expected to confer benefits on patients with constipation, but how probiotics act on constipated patients with variable stool consistencies remains unclear. We investigated the effect of Lactobacillus...
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Red fluorescence of oral bacteria is affected by blood in the growth medium

Jeong SH, Yang YH, Lee MA, Kim SY, Kim JS

OBJECTIVES: Dental plaque emits red fluorescence under a visible blue light near the ultra-violet end of the light spectrum. The fluorescence characteristics of each microorganism have been reported in several...
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Red fluorescence of oral bacteria interacting with Porphyromonas gingivalis

Kim SY, Woo DH, Lee MA, Kim JS, Lee JH, Jeong SH

OBJECTIVES: Dental plaque is composed of 700 bacterial species. It is known that some oral microorganisms produce porphyrin, and thus, they emit red fluorescence when illuminated with blue light at...
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Lactobacillus casei strain C1 attenuates vascular changes in spontaneously hypertensive rats

Yap WB, Ahmad FM, Lim YC, Zainalabidin S

Hypertension can be caused by various factors while the predominant causes include increase in body fluid volume and resistance in the circulatory system that elevate the blood pressure. Consumption of...
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The growth inhibitory effect of some vegetable oils on Streptococcus mutans and Lactobacillus casei

Kim SY, Kim HN, Jun EJ, Kim JB, Jeong SH

OBJECTIVES: The purpose of this study was to evaluate the growth inhibitory effects of some vegetable oils on Streptococcus mutans (S. mutans) and Lactobacillus casei (L. casei). METHODS: Two bacterial strains...
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Beneficial Effects of Lactobacillus casei ATCC 334 on Halitosis Induced by Periodontopathogens

Lee KH, Baek DH

  • KMID: 1703489
  • Int J Oral Biol.
  • 2014 Mar;39(1):35-40.
Halitosis is caused by consumption of certain foods or drinks and production of volatile sulfur compounds (VSCs) by periodontopathogens. VSCs-related halitosis is not easily removed using mechanical or chemical therapies...
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Characterization of two antimicrobial peptides identified from a random peptide library and expressed in the methylotrophic yeast pichia pastoris

Jeon IS, Song KD, Oh JD, Choi JK

  • KMID: 1703518
  • J Biomed Res.
  • 2013 Dec;14(4):235-239.
Antimicrobial peptides (AMPs) are an important component of innate defense mechanisms with broad-spectrum activities against various pathogenic microorganisms, including Gram-positive and Gram-negative bacteria, fungi, and viruses. Antibiotic resistance has become...
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Growth Inhibition of Hepatocellular Carcinoma Huh7 Cells by Lactobacillus casei Extract

Han DJ, Kim JB, Park SY, Yang MG, Kim H

PURPOSE: Lactobacillus casei (L. casei) is known to exert anti-proliferation effects on many types of cancer cells. However, the effect of L. casei on liver cancer has not been reported....
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Immunogenicity of a Canine Parvovirus 2 Capsid Antigen (VP2-S1) surface-expressed on Lactobacillus casei

Moon HJ, Chowdhury , Kim CJ, Shin KS

  • KMID: 1498927
  • J Biomed Res.
  • 2013 Jun;14(2):91-98.
Canine parvovirus (CPV2) is one of the most virulent virus causing acute hemorrhagic enteritis and myocarditis in dogs. Infection mainly caused by the ingestion of virus through the mucosal route....
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Effect of Probiotics on the Treatment of Children with Atopic Dermatitis

Yesilova Y, Calka O, Akdeniz N, Berktas M

  • KMID: 2434685
  • Ann Dermatol.
  • 2012 May;24(2):189-193.
BACKGROUND: Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. In the last 30 years, the prevalence of atopic dermatitis has rapidly increased due to industrialization. Therefore,...
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Adhesion Activity of Lactobacillus plantarum PM 008 Isolated from Kimchi on the Intestine of Mice

Jang SE, Hyun YJ, Oh YJ, Choi KB, Kim T, Yeo IH, Han MJ, Kim DH

Lactic acid bacteria (LAB), including L. plantarum isolated from Kimchi, are beneficial and safe microorganisms that improve disturbances of the indigenous microflora and the host's immune system. The adhesion abilities...
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The Effects of Lactobacillus rhamnosus on the Prevention of Asthma in a Murine Model

Yu J, Jang SO, Kim BJ, Song YH, Kwon JW, Kang MJ, Choi WA, Jung HD, Hong SJ

PURPOSE: Lactobacilli are probiotic bacteria that are effective in the management of allergic diseases or gastroenteritis. It is hypothesized that such probiotics have immunoregulatory properties and promote mucosal tolerance. Our...
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Inhibition of Aflatoxin Production of Aspergillus flavus by Lactobacillus casei

Chang I, Kim JD

  • KMID: 2383711
  • Mycobiology.
  • 2007 Jun;35(2):76-81.
Lactobacillus casei KC-324 was tested for its ability to inhibit aflatoxin production and mycelial growth of Aspergillus flavus ATCC 15517 in liquid culture. Aflatoxin B1 biosynthesis and mycelial growth were...
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The Effects on Treatment of Atopic Dermatitis with Oral Lactobacillus casei Supplements in Korean Children

Kong DY, Yang HJ, Pyun BY

  • KMID: 2314452
  • Pediatr Allergy Respir Dis.
  • 2007 Mar;17(1):27-37.
PURPOSE: Recent studies suggest that oral probiotic administration might be useful in the management of atopic dermatitis. Probiotics are known to promote the maturation of gut- associated lymphoid tissue (GALT)...
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Probiotics may Reduce Inflammation by Enhancing Peroxisome Proliferator Activated Receptor gamma Activation in HT-29 Cells

Eun CS, Han DS, Lee SH, Jeon YC, Sohn JH, Kim YS, Lee J

  • KMID: 782835
  • Korean J Gastroenterol.
  • 2007 Mar;49(3):139-146.
BACKGROUND/AIMS: The peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor highly expressed in the colon which plays an anti-inflammatory role through the inhibition of nuclear factor-kappaB (NF-kappaB) pathway. Probiotics...
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An Update on Kawasaki disease (Research): Animal Model

Han JW

  • KMID: 2201175
  • J Korean Pediatr Cardiol Soc.
  • 2006 Dec;10(4):391-401.
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology in young children. There has been many trials to find out the causes of KD all over the world since...
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Antifungal Activity of Lactic Acid Bacteria Isolated from Kimchi Against Aspergillus fumigatus

Kim JD

  • KMID: 2312471
  • Mycobiology.
  • 2005 Dec;33(4):210-214.
More than 120 isolates of lactic acid bacteria obtained from Kimchi was screened for antifungal activity against Aspergillus fumigatus. Approximately 10% of the isolates showed inhibitory activity and only 4.16%...
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Comparison of Lactobacillus casei in Stool between Children with Atopic Dermatitis and Normal Controls

Kim DY, Shin YS, Kong DY, Pyun BY

  • KMID: 1592979
  • Pediatr Allergy Respir Dis.
  • 2004 Jun;14(2):160-166.
PURPOSE: As allergy diseases including atopic dermatitis are increasing lately, many kinds of studies about the cause and the pathogenesis are in progress and the secrets of the of organization...
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