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A Case of Pneumonia Caused by Pneumocystis jirovecii Resistant to Trimethoprim/Sulfamethoxazole in the Absence of Previous Drug Exposure

Ahn A, Chang J, Sung H, Kim MN

  • Lab Med Online.
  • 2016 Oct;6(4):250-254.
  • doi: 10.3343/lmo.2016.6.4.250
Pneumocystis jirovecii pneumonia is a common opportunistic infection seen in patients with human immunodeficiency virus (HIV) infection. Dihydropteroate synthase (DHPS) is a target of sulfa drugs, and mutations in DHPS...
Two Concurrent Chromosomal Aberrations Involving Three-way t(3;21;8)(p21;q22;q22) and Two-way t(2;11)(q31;p15) Translocations in a Case of de novo Acute Myeloid Leukemia

Park GC, Cho EH, Kang SH, Jang SJ, Moon DS, Park G

  • Lab Med Online.
  • 2016 Oct;6(4):246-249.
  • doi: 10.3343/lmo.2016.6.4.246
One of the most frequent structural chromosomal anomaly is t(8;21)(q22;q22) that occurs in approximately 5-15% of all acute myeloid leukemia (AML). However, t(3;21)(p21;q22) and t(2;11)(q31;p15) translocations are rarely reported in...
Comparison of the Ability of Multiplex and Singleplex PCR to Detect Human Respiratory Viruses

Kim S, Eom KW, Cho CR, Um TH

  • Lab Med Online.
  • 2016 Oct;6(4):240-245.
  • doi: 10.3343/lmo.2016.6.4.240
BACKGROUND: The use of the multiplex polymerase chain reaction (PCR) technique for respiratory viruses has become popular in Korea owing to its convenience and sensitivity. However, concerns remain with regard...
Performance Evaluation of Two Automated Quantitative Fecal Occult Blood Tests

Ahn A, Kim J, Ko YJ, Sung H, Kim MN

  • Lab Med Online.
  • 2016 Oct;6(4):233-239.
  • doi: 10.3343/lmo.2016.6.4.233
BACKGROUND: The performance of the fecal occult blood test (FOBT) has recently improved with the use of quantitative immunochemical assays. We evaluated the two latest immunochemical FOBTs: OC-Sensor PLEDIA (Eiken...
Changing Guidelines for Clinical Microbiology Laboratories and Their Influences on Workflows Related to Consultations

Ahn S, Kim H, Sung JY, Kim MS, Yong D, Lee K

  • Lab Med Online.
  • 2016 Oct;6(4):228-232.
  • doi: 10.3343/lmo.2016.6.4.228
BACKGROUND: Since the concept of 'minimal identification of poor quality specimens or microbes with low pathogen potential' has been introduced into the standard operating procedure (SOP) to enhance work efficiency,...
Association of Homocysteine Levels with Subclinical Coronary Atherosclerosis in Asymptomatic Subjects

Nah EH, Cho HI, Choi JC

  • Lab Med Online.
  • 2016 Oct;6(4):221-227.
  • doi: 10.3343/lmo.2016.6.4.221
BACKGROUND: Progression of atherosclerotic plaques is known to be correlated with elevated circulating homocysteine (Hcy). However, whether the level of Hcy is related with coronary atherosclerosis in the subclinical state...
Monitoring the Antiplatelet Effect of Cilostazol with Light Transmission Aggregometer: Two Cases of Possible Cilostazol Resistance

Shim H, Jang S, Park CJ, Chi HS, Lee SW, Park SW

  • Lab Med Online.
  • 2016 Oct;6(4):214-220.
  • doi: 10.3343/lmo.2016.6.4.214
BACKGROUND: Coronary artery disease is an important cause of death in adults and stent insertion is one of the treatment modalities. The most severe adverse effect of a stent insertion...
Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines Part 2

Kim S, Yun YM, Kim IS, Song SH, Woo HI, Lee KA, Lee W, Cho HJ, Ji M, Chae HJ, Lee SY, Chun S

  • Lab Med Online.
  • 2016 Oct;6(4):193-213.
  • doi: 10.3343/lmo.2016.6.4.193
Pharmacogenetics is a rapidly evolving field and the number of pharmacogenetic tests for clinical use is steadily increasing. However, incorrect or inadequate implementation of pharmacogenetic tests in clinical practice may...

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