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A Case of Pneumonia Caused by Pneumocystis jirovecii Resistant to Trimethoprim/Sulfamethoxazole in the Absence of Previous Drug Exposure

Ahn A, Chang J, Sung H, Kim MN

Pneumocystis jirovecii pneumonia is a common opportunistic infection seen in patients with human immunodeficiency virus (HIV) infection. Dihydropteroate synthase (DHPS) is a target of sulfa drugs, and mutations in DHPS...
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Two Concurrent Chromosomal Aberrations Involving Three-way t(3;21;8)(p21;q22;q22) and Two-way t(2;11)(q31;p15) Translocations in a Case of de novo Acute Myeloid Leukemia

Park GC, Cho EH, Kang SH, Jang SJ, Moon DS, Park G

One of the most frequent structural chromosomal anomaly is t(8;21)(q22;q22) that occurs in approximately 5-15% of all acute myeloid leukemia (AML). However, t(3;21)(p21;q22) and t(2;11)(q31;p15) translocations are rarely reported in...
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Comparison of the Ability of Multiplex and Singleplex PCR to Detect Human Respiratory Viruses

Kim S, Eom KW, Cho CR, Um TH

BACKGROUND: The use of the multiplex polymerase chain reaction (PCR) technique for respiratory viruses has become popular in Korea owing to its convenience and sensitivity. However, concerns remain with regard...
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Performance Evaluation of Two Automated Quantitative Fecal Occult Blood Tests

Ahn A, Kim J, Ko YJ, Sung H, Kim MN

BACKGROUND: The performance of the fecal occult blood test (FOBT) has recently improved with the use of quantitative immunochemical assays. We evaluated the two latest immunochemical FOBTs: OC-Sensor PLEDIA (Eiken...
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Changing Guidelines for Clinical Microbiology Laboratories and Their Influences on Workflows Related to Consultations

Ahn S, Kim H, Sung JY, Kim MS, Yong D, Lee K

BACKGROUND: Since the concept of 'minimal identification of poor quality specimens or microbes with low pathogen potential' has been introduced into the standard operating procedure (SOP) to enhance work efficiency,...
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Association of Homocysteine Levels with Subclinical Coronary Atherosclerosis in Asymptomatic Subjects

Nah EH, Cho HI, Choi JC

BACKGROUND: Progression of atherosclerotic plaques is known to be correlated with elevated circulating homocysteine (Hcy). However, whether the level of Hcy is related with coronary atherosclerosis in the subclinical state...
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Monitoring the Antiplatelet Effect of Cilostazol with Light Transmission Aggregometer: Two Cases of Possible Cilostazol Resistance

Shim H, Jang S, Park CJ, Chi HS, Lee SW, Park SW

BACKGROUND: Coronary artery disease is an important cause of death in adults and stent insertion is one of the treatment modalities. The most severe adverse effect of a stent insertion...
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Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines Part 2

Kim S, Yun YM, Kim IS, Song SH, Woo HI, Lee KA, Lee W, Cho HJ, Ji M, Chae HJ, Lee SY, Chun S

Pharmacogenetics is a rapidly evolving field and the number of pharmacogenetic tests for clinical use is steadily increasing. However, incorrect or inadequate implementation of pharmacogenetic tests in clinical practice may...
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