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Fluorescence Quenching to Measure dDAVP-induced Cell Volume Changes in Kidney Collecting Duct Cell

Choi HJ, Kwon TH

  • KMID: 2080003
  • Korean J Nephrol.
  • 2009 Jul;28(4):317-325.
PURPOSE: Cell volume regulation is critical in kidney collecting duct cells which are subjected to large transepithelial osmotic gradients and stimulation of vasopressin. The present study aimed at validating the...
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Ubiquitination of Aquaporin: in the kidney

Lee YJ, Kwon TH

Ubiquitination is known to be important for endocytosis and lysosomal degradation of aquaporin-2 (AQP2). Ubiquitin (Ub) is covalently attached to the lysine residue of the substrate proteins and activation and...
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Duplicated Collecting System with Lower Pole Ureteropelvic Junct ion Obstruction

Ko WJ, Hong CH, Han SW

Two examples of the rare case of complete duplicated collecting system with lower pole ureteropelvic junction obstruction are described. Ureteropelvic junction obstruction (UPJO) and duplicated collecting systems seldom occur in...
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A Minireview on Vasopressin-regulated Aquaporin-2 in Kidney Collecting Duct Cells

Park EJ, Kwon TH

The kidney collecting duct is an important renal tubular segment for the regulation of body water and salt homeostasis. Water reabsorption in the collecting duct cells is regulated by arginine...
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Renal Handling of Ammonium and Acid Base Regulation

Kim HY

Renal ammonium metabolism is the primary component of net acid excretion and thereby is critical for acid - base homeostasis. Briefly, ammonium is produced from glutamine in the proximal tubule...
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Dexamethasone enhances phospholipase D activity in M-1 cells

Kim WJ, Lee MJ, Park MA, Jung JS, Uhlinger D, Kwak JY

  • KMID: 755082
  • Exp Mol Med.
  • 2000 Sep;32(3):170-177.
Phospholipase D (PLD) is an enzyme involved in signal transduction and widely distributed in mammalian cells. The signal transduction pathways and role for phospholipid metabolism during hormonal response in...
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Expression of Rh Glycoproteins in the Mammalian Kidney

Han KH, Kim HY, Weiner D

Ammonia metabolism is a fundamental process in the maintenance of life in all living organisms. Recent studies have identified ammonia transporter family proteins in yeast (Mep), plants (Amt), and mammals...
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Immunolocalization of anion exchanger 1 (Band 3) in the renal collecting duct of the common marmoset

Song JH, Kim YH, Kang TC, Won MH, Suh JG, Hyun BH, Oh YS, Ryu SY, Jung JY

The purpose of this study was to determine the expression and distribution of band 3 in the collecting duct and connecting tubules of the kidney of the marmoset monkey (Callithrix...
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Ultrastructural Localization of the Ammonia Transporter Protein, RhCG, in Rat Kidney Collecting Duct

Han KH, Song HK, Kim J

  • KMID: 1564373
  • Korean J Anat.
  • 2005 Aug;38(4):345-352.
Ammonia excretion in the renal collecting duct is critical in the regulation of the acid-base homeostasis. A novel family of ammonium transporter protein, Rh C Glycoprotein (RhCG) was recently identified...
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Ultrastructural Localization of the Ammonium Transporter Protein, RhBG, in the Intercalated Cell of Rat Kidney Collecting Duct

Han KH, Kim WY, Verlander , Weiner ID, Kim J

  • KMID: 1564268
  • Korean J Anat.
  • 2005 Apr;38(2):167-172.
Ammonia excretion in the renal collecting duct is critical in the regulation of the acid-base homeostasis. A novel family of ammonium transporter protein, Rh B Glycoprotein (RhBG) was recently identified...
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New insights into the transcriptional regulation of aquaporin-2 and the treatment of X-linked hereditary nephrogenic diabetes insipidus

Jung HJ, Kwon TH

The kidney collecting duct (CD) is a tubular segment of the kidney where the osmolality and final flow rate of urine are established, enabling urine concentration and body water homeostasis....
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Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice

Choi A, Nam SA, Kim WY, Park SH, Kim H, Yang CW, Kim J, Kim YK

BACKGROUND/AIMS: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important...
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Renal Expression of Ammonia Transporters in Rats with Amiloride-Induced Renal Tubular Acidosis

Kim SJ, Kim HY, Choi JH, Kim JT, Kim JE, Yeon MH, Kim SM, Kwon SK, Shin KS

  • KMID: 2259292
  • Korean J Med.
  • 2011 Jun;80(6):687-696.
BACKGROUND/AIMS: Renal tubular acidosis (RTA) decreases the net acid excretion, predominantly due to a decrease in urinary ammonia excretion. This study examined whether this decrement is associated with changes in...
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Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160

Jung HJ, Kwon TH

  • KMID: 2406195
  • Electrolyte Blood Press.
  • 2010 Dec;8(2):59-65.
Akt (protein kinase B (PKB)) is a serine/threonine kinase that acts in the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway. The PI3K/Akt signaling pathway, triggered by growth factors and hormones including vasopressin,...
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