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Successful wheat-specific oral immunotherapy in highly sensitive individuals with a novel multirush/maintenance regimen

Pacharn P, Siripipattanamongkol N, Veskitkul , Jirapongsananuruk O, Visitsunthorn N, Vichyanond P

We reported a successful oral immunotherapy (OIT) in 2 children with high wheat sensitivity (4 and 14 years old boys). Oral challenges indicated eliciting doses of 300 mg, and wheat...
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Carrying rates of epinephrine devices in children with food-induced anaphylaxis

Ratanaprug C, Srisuwatchari W, Jirapongsananuruk O, Visitsunthorn N, Pacharn P

BACKGROUND: Carrying epinephrine can save lives in patients with anaphylaxis. The feature of epinephrine in prefilled syringe that commonly prescribed in Thailand may influence the willingness to carry. However, the...
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The Effect of Vitamin D Status on Pediatric Asthma at a University Hospital, Thailand

Krobtrakulchai W, Praikanahok J, Visitsunthorn N, Vichyanond P, Manonukul , Pratumvinit B, Jirapongsananuruk O

PURPOSE: In the USA and Europe, hypovitaminosis D is associated with increased asthma severity, emergency department (ED) visit, and impaired pulmonary function in asthmatic patients. However, in tropical countries, data...
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The Utility of Serum Tryptase in the Diagnosis of Food-Induced Anaphylaxis

Wongkaewpothong P, Pacharn P, Sripramong C, Boonchoo S, Piboonpocanun S, Visitsunthorn N, Vichyanond P, Jirapongsananuruk O

PURPOSE: This study investigates the utility of serum tryptase for the confirmation of shrimp-induced anaphylaxis. METHODS: Patients with a history of shrimp allergy and positive skin prick tests (SPT) to commercial...
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Effect of Amino Acid Polymorphisms of House Dust Mite Der p 2 Variants on Allergic Sensitization

Tanyaratsrisakul S, Jirapongsananuruk O, Kulwanich , Hales BJ, Thomas WR, Piboonpocanun S

PURPOSE: The sequence variations of the Der p 2 allergen of Dermatophagoides pteronyssinus diverge along 2 pathways with particular amino acid substitutions at positions 40,47,111, and 114. The environmental prevalence...
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Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

Kulwanich , Thanyaratsrisakul S, Jirapongsananuruk O, Hales BJ, Thomas WR, Piboonpocanun S

PURPOSE: Hypoallergenic recombinant Der p 2 has been produced by various genetic manipulations, but mutation of a naturally polymorphic amino acid residue known to affect IgE binding has not been...
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