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Limited Clinical Significance of Splenectomy and Splenic Hilar Lymph Node Dissection for Type 4 Gastric Cancer

Kunitomo A, Misawa K, Ito Y, Ito S, Higaki E, Natsume S, Kinoshita T, Abe T, Komori K, Shimizu Y

Purpose: Type 4 gastric cancer (GC) has a very poor prognosis even after curative resection, and the survival benefit of splenectomy for splenic hilar lymph node (LN; #10) dissection in...
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A Single Bout of Constant-Load Exercise Test for Estimating the Time Constant of Oxygen Uptake Kinetics in Individuals With Stroke

Oyake K, Baba Y, Suda Y, Murayama J, Mochida A, Ito Y, Abe H, Kondo K, Otaka Y, Momose K

Objective To examine the relationship between the time constant of oxygen uptake kinetics during the onset of exercise (τVO2) estimated from a single exercise bout and that obtained from three...
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Salicylamide Enhances Melanin Synthesis in B16F1 Melanoma Cells

Ito Y, Sato K

Salicylamide, a non-steroidal anti-inflammatory drug (NSAID), is used as an analgesic and antipyretic agent. We have previously shown that several NSAIDs have anti-melanogenic properties in B16F1 melanoma cells. In contrast,...
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Hepatosplenic T-Cell Lymphoma Diagnosed by Endoscopic Ultrasound-Guided Fine-Needle Biopsy

Shibata Y, Miyamoto M, Shinomiya W, Kirita K, Motomura S, Hidai H, Hagino T, Ito Y

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Molecular Prevalence of Cryptosporidium spp. among Companion Birds Kept in Pet Shops in Japan

Iijima Y, Itoh N, Phrompraphai T, Ito Y, Kimura Y, Kameshima

Cryptosporidium is the most common protozoan that can infect a wide range of animals, including mammals and birds. Avian Cryptosporidium spp. can cause enteric and respiratory diseases which can be...
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A Novel Partially Covered Self-Expandable Metallic Stent with Proximal Flare in Patients with Malignant Gastric Outlet Obstruction

Takahara N, Isayama H, Nakai Y, Yoshida S, Saito T, Mizuno S, Yagioka H, Kogure H, Togawa O, Matsubara , Ito Y, Yamamoto N, Tada M, Koike K

BACKGROUND/AIMS: Endoscopic placement of self-expandable metal stents (SEMSs) has emerged as a palliative treatment for malignant gastric outlet obstruction (GOO). Although covered SEMSs can prevent tumor ingrowth, frequent migration of...
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Endoscopic ultrasound-guided biliary drainage: Complications and their management

Isayama H, Nakai Y, Yamamoto N, Matsubara , Ito Y, Kogure H, Hamada T, Koike K

Endoscopic ultrasound-guided biliary drainage (EUS-BD), EUS-guided choledochoduodenostomy (EUS-CDS), and EUS-guided hepaticogastrostomy (EUS-HGS) can effectively palliate obstructive jaundice, but have not been well established yet. The incidence of complications is about...
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Antireflux Metal Stent as a First-Line Metal Stent for Distal Malignant Biliary Obstruction: A Pilot Study

Hamada T, Isayama H, Nakai Y, Togawa O, Takahara N, Uchino R, Mizuno S, Mohri D, Yagioka H, Kogure H, Matsubara , Yamamoto N, Ito Y, Tada M, Koike K

BACKGROUND/AIMS: In distal malignant biliary obstruction, an antireflux metal stent (ARMS) with a funnel-shaped valve is effective as a reintervention for metal stent occlusion caused by reflux. This study sought...
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Successful Endosonography-Guided Drainage of an Intra-Abdominal Abscess in a 1-Year-Old Infant

Ito Y, Isayama H, Nakai Y, Umefune G, Sato T, Nakahara S, Suwa J, Kato K, Nakata R

Endoscopic ultrasound (EUS)-guided intervention has been established as a safe, effective and minimally invasive procedure for various diseases in adults, but there have been limited reports in pediatric patients. Herein,...
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Postoperative portal vein thrombosis and gastric hemorrhage associated with late-onset hemorrhage from the common hepatic artery after pancreaticoduodenectomy

Watanobe I, Ito Y, Akimoto E, Sekine Y, Haruyama Y, Amemiya K, Miyano S, Kosaka T, Machida M, Kitabatake T, Kojima K

Portal vein thrombosis (PVT) is a rare but serious postoperative complication of pancreaticoduodenectomy (PD). We reported a case of late-onset postoperative PVT with hemorrhage from the common hepatic artery (CHA)...
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A Novel, Fully Covered Laser-Cut Nitinol Stent with Antimigration Properties for Nonresectable Distal Malignant Biliary Obstruction: A Multicenter Feasibility Study

Isayama H, Kawakubo K, Nakai Y, Inoue K, Gon C, Matsubara , Kogure H, Ito Y, Tsujino T, Mizuno S, Hamada T, Uchino R, Miyabayashi K, Yamamoto K, Sasaki T, Yamamoto N, Hirano K, Sasahira N, Tada M, Koike K

  • KMID: 1712334
  • Gut Liver.
  • 2013 Nov;7(6):725-730.
BACKGROUND/AIMS: Stent migration occurs frequently, but the prevention of complications resulting from covered self-expandable metal stents (C-SEMSs) remains unresolved. We prospectively assessed a newly developed C-SEMS, a modified covered Zeo...
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Percutaneous Transhepatic Biliary Drainage Using a Ligated Catheter for Recurrent Catheter Obstruction: Antireflux Technique

Hamada T, Tsujino T, Isayama H, Hakuta R, Ito Y, Nakata R, Koike K

  • KMID: 2135080
  • Gut Liver.
  • 2013 Mar;7(2):255-257.
Percutaneous transhepatic biliary drainage (PTBD) is an established procedure for biliary obstruction. However, duodenobiliary or jejunobiliary reflux of the intestinal contents through a PTBD catheter sometimes causes recurrent catheter obstruction...
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Motion Induced Artifact Mimicking Cervical Dens Fracture on the CT Scan: A Case Report

Sugimoto Y, Ito Y, Shiozaki Y, Shimokawa , Mazaki T

The diagnostic performance of helical computed tomography (CT) is excellent. However, some artifacts have been reported, such as motion, beam hardening and scatter artifacts. We herein report a case of...
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Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding

Yamada S, Kuraoka S, Osano A, Ito Y

  • KMID: 2232961
  • Int Neurourol J.
  • 2012 Sep;16(3):107-115.
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin...
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Surgical Treatment for Papillary Thyroid Carcinoma in Japan: Differences from Other Countries

Ito Y, Miyauchi A

  • KMID: 2198454
  • J Korean Thyroid Assoc.
  • 2011 Nov;4(2):75-79.
Papillary thyroid carcinoma (PTC) is the most representative carcinoma among thyroid malignancies. The treatment strategy, especially surgery, in Japan traditionally differs from that in other countries, including Korea. Total thyroidectomy...
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Beta agonist regulation of sodium transport in fetal lung epithelium: roles of cell volume, cytosolic chloride and protein tyrosine kinase

Marunaka Y, Niisato N, Ito Y

1) A beta agonist stimulated Na+ transport and decreased the intracellular Cl concentration ([Cl]c) associated with cell shrinkage via an increase in cytosolic cAMP level by activating adenylate cyclase in...
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