Gut Liver.  2017 Jan;11(1):142-148. 10.5009/gnl15579.

Antireflux Metal Stent as a First-Line Metal Stent for Distal Malignant Biliary Obstruction: A Pilot Study

Affiliations
  • 1Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. isayama-tky@umin.ac.jp
  • 2Department of Gastroenterology, Tokyo Metropolitan Police Hospital, Tokyo, Japan.
  • 3Department of Gastroenterology, Japanese Red Cross Medical Center, Tokyo, Japan.

Abstract

BACKGROUND/AIMS
In distal malignant biliary obstruction, an antireflux metal stent (ARMS) with a funnel-shaped valve is effective as a reintervention for metal stent occlusion caused by reflux. This study sought to evaluate the feasibility of this ARMS as a first-line metal stent.
METHODS
Patients with nonresectable distal malignant biliary obstruction were identified between April and December 2014 at three Japanese tertiary centers. We retrospectively evaluated recurrent biliary obstruction and adverse events after ARMS placement.
RESULTS
In total, 20 consecutive patients were included. The most common cause of biliary obstruction was pancreatic cancer (75%). Overall, recurrent biliary obstruction was observed in seven patients (35%), with a median time to recurrent biliary obstruction of 246 days (range, 11 to 246 days). Stent occlusion occurred in five patients (25%), the causes of which were sludge and food impaction in three and two patients, respectively. Stent migration occurred in two patients (10%). The rate of adverse events associated with ARMS was 25%: pancreatitis occurred in three patients, cholecystitis in one and liver abscess in one. No patients experienced non-occlusion cholangitis.
CONCLUSIONS
The ARMS as a first-line biliary drainage procedure was feasible. Because the ARMS did not fully prevent stent dysfunction due to reflux, further investigation is warranted.

Keyword

Antireflux; Biliary obstruction; Covered; Cholangiopancreatography, endoscopic retrograde; Metal stent

MeSH Terms

Aged
Aged, 80 and over
*Cholangiopancreatography, Endoscopic Retrograde
Cholestasis/etiology/*surgery
Common Bile Duct Neoplasms/complications/*surgery
Female
Gallbladder Neoplasms/complications/*surgery
Humans
Japan
Lymphatic Metastasis
Male
Pancreatic Neoplasms/complications/*surgery
Pilot Projects
*Prosthesis Design
Retrospective Studies
*Self Expandable Metallic Stents
Full Text Links
  • GNL
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr