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Integrins Mediating Adhesion and Proliferation of ADP-stimulated Vascular Smooth Muscle Cells

Joo SJ, Cha TJ, Lee JW

BACKGROUND AND OBJECTIVES: Adenosine diphosphate (ADP), which is usually secreted from activated platelets, may activate integrins on vascular smooth muscle cells, resulting in adhesion and proliferation. Integrins, mediating the ADP-stimulated...
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Effects of nitric oxide on the proliferation and differentiation of human periodontal ligament cells

Choi SY, Cho JH, Kang KH

  • KMID: 1513132
  • Korean J Orthod.
  • 2006 Dec;36(6):465-473.
OBJECTIVE: This study evaluated the effects of nitric oxide (NO) on the proliferation and differentiation of human periodontal ligament cells involved in orthodontic tooth movement. METHODS: A range of concentrations...
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Effects of irradiation on the mRNA expression of osteonectin and bone sialoprotein in MC3T3-E1 osteoblastic cell line

Ha SY, Kang KH, Lee SR, Kwon KJ, Koh KJ

  • KMID: 1515551
  • Korean J Oral Maxillofac Radiol.
  • 2004 Jun;34(2):99-106.
PURPOSE: To investigate the effects of irradiation on the phenotypic expression of the MC3T3-E1 osteoblastic cell line, especially on the osteonectin and bone sialoprotein. MATERIALS AND METHODS: Cells were irradiated...
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Osteoblastic differentiation of adult stem cells by Biphasic Calcium Phosphate

Lee MK, Lim SW, Pi SH, Kim YS, Shin HS, You HK

The present study was to determine the influence of micro-macro biphasic calcium phosphate(MBCP) on proliferation and differentiation of human marrow-derived mesenchymal stem cells. Primary stem cells were cultured from bone...
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Study on the Biological Characteristics of Cultured Osteoblasts Derived from Alveolar Bone

Lee YB, Lee SJ, You SJ, Kim HA, You HK, Shin HS

Osteoblasts from alveolar bone may have an important role in the bone regeneration for periodontium, but their culture and characterization are not determined yet. The purpose of this study was...
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Osteogenic Gene Expression on Anodizing Titanium Surface

Kim W, Kim YS, Jeon S, Jun S, Lee E, Jang H, Kwon J, Rim J

  • KMID: 1434420
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2012 Mar;34(2):91-99.
PURPOSE: The purpose of this study was to evaluate the expression of osteogenic genes associated with bone regeneration on anodizing titanium surface. METHODS: 20x20x1 (mm) commercially pure titanium plate was made,...
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Heat or radiofrequency plasma glow discharge treatment of a titanium alloy stimulates osteoblast gene expression in the MC3T3 osteoprogenitor cell line

Rapuano BE, Hackshaw K, MacDonald

PURPOSE: The purpose of this study was to determine whether increasing the Ti6Al4V surface oxide negative charge through heat (600degrees C) or radiofrequency plasma glow discharge (RFGD) pretreatment, with or...
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Effects of CoCl2 on Osteogenic Differentiation of Human Mesenchymal Stem Cells

Moon YH, Son JW, Moon JS, Kang JH, Kim SH, Kim MS

  • KMID: 2170781
  • Int J Oral Biol.
  • 2013 Sep;38(3):111-119.
OBJECTIVE: To investigate the effects of the hypoxia inducible factor-1 (HIF-1) activation-mimicking agent cobalt chloride (CoCl2) on the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and elucidate the underlying...
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Effects of Ipriflavone on bone remodeling in the rat calvarial cell

Lee YS, Kim YJ, Lee KH, Hwang HS

  • KMID: 1762554
  • Korean J Orthod.
  • 2005 Aug;35(4):275-285.
Ipriflavone (isoprofoxyisoflavone), a synthetic derivative from soy isoflavone diazein, has been shown to inhibit bone resorption and perhaps stimulate bone formation. This study was performed to examine the effects of...
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Effects of 2-deoxy-D-glucose and quercetin on the gene expression of bone sialoprotein and osteocalcin during the differentiation in irradiated MC3T3-E1 osteoblastic cells

Lee JU, Kim KA, Koh KJ

  • KMID: 2034179
  • Korean J Oral Maxillofac Radiol.
  • 2009 Sep;39(3):121-132.
PURPOSE: To investigate the effects of 2-deoxy-D-glucose (2-DG) and quercetin (QCT) on gene expression of bone sialoprotein (BSP) and osteocalcin (OC) during the differentiation in irradiated MC3T3-E1 osteoblastic cells. MATERIALS AND...
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Barium Stimulates the Expression of Osteogenic Genes in Human Mesenchymal Stem Cells into Osteoblasts in vitro

Ahn KH, Jung SE, Yi KW, Park HT, Shin JH, Kim YT, Hur JY, Kim SH, Kim T

  • KMID: 2201113
  • J Korean Soc Menopause.
  • 2011 Aug;17(2):81-87.
OBJECTIVES: The purpose of this study was to determine the effect of barium on gene expression in differentiation of human mesenchymal stem cells into osteoblasts in vitro. METHODS: Human bone marrow...
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Effect of chitosan on bone matrix expression and mineralization in primary rat calvarial cell

Kim JC, Ciu DZ, Kim YJ, Chung HJ, Kim OS

Periodontal therapy has dealt primarily with attempts at arresting progression of disease, however, more recent techniques have focused on regenerating the periodontal ligament having the capacity to regenerate the periodontium....
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Response of osteoblast-like cells cultured on zirconia to bone morphogenetic protein-2

Han SH, Kim KH, Han JS, Koo KT, Kim TI, Seol YJ, Lee YM, Ku Y, Rhyu IC

PURPOSE: The aim of this study was to compare osteoblast behavior on zirconia and titanium under conditions cultured with bone morphogenetic protein-2. METHODS: MC3T3-E1 cells were cultured on sandblasted zirconia and...
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The effect of rhBMP-2 on the osteoblastic differentiation of human periodontal ligament cells and gingival fibroblasts in vitro

Kim HJ, Choi SM, Ku Y, Rhyu IC, Chung CP, Han SB, Kim KH, Lee YM

BMP can induce ectopic bone formation when implanted into sites such as rat muscle and can greatly enhance healing of bony defects when applied exogenously. In addition, BMP stimulated osteoblastic...
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The effects of bone morphogenetic protein-2 and enamel matrix derivative on the bioactivity of mineral trioxide aggregate in MC3T3-E1cells

Jeong Y, Yang W, Ko H, Kim M

  • KMID: 2316893
  • Restor Dent Endod.
  • 2014 Aug;39(3):187-194.
OBJECTIVES: The effects of bone morphogenetic protein-2 (BMP-2) and enamel matrix derivative (EMD) respectively with mineral trioxide aggregate (MTA) on hard tissue regeneration have been investigated in previous studies. This...
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Osteoblastic behavior to zirconium coating on Ti-6Al-4V alloy

Lee BA, Kim HJ, Xuan YZ, Park YJ, Chung HJ, Kim YJ

PURPOSE: The purpose of this study was to assess the surface characteristics and the biocompatibility of zirconium (Zr) coating on Ti-6Al-4V alloy surface by radio frequency (RF) magnetron sputtering method. MATERIALS...
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The effect of rhBMP-2 in human bone marrow-derived stem cells as osteogenic inducers

Kim IS, Zhang YL, Cho TH, Lee KB, Park YD, Rho IS, Weber F, Hwang SJ, Kim MJ, Lee JH

  • KMID: 2183842
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2005 Jan;27(1):16-23.
It is commonly acknowledged that bone morphogenic protein (BMP-2) functions as a potential osteogenic inducer in bone formation. Recently, several papers reported that bone marrow-derived stem cell (BMSC) from...
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Effect of magnesium and calcium phosphate coatings on osteoblastic responses to the titanium surface

Park KD, Lee BA, Piao XH, Lee KK, Park SW, Oh HK, Kim YJ, Park HJ

PURPOSE: The aim of this study was to evaluate the surface properties and in vitro bioactivity to osteoblasts of magnesium and magnesium-hydroxyapatite coated titanium. MATERIALS AND METHODS: Themagnesium (Mg) and magnesium-hydroxyapatite...
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The effects of beta-TCP/rhBMP-2 on bone formation in osteoblast-like cells induced from bone marrow-derived mesenchymal stem cells

Choi YS, Hwang KG, Lee JS, Park CJ, Shim KS

  • KMID: 2190170
  • J Korean Assoc Oral Maxillofac Surg.
  • 2008 Aug;34(4):419-427.
The present study aimed to investigate the osteogenic potentials of differentiated osteoblast-like cells (DOCs) induced from bone marrow-derived mesenchymal stem cells (MSCs) on beta-tricalcium phosphate (beta-TCP) with recombinant human bone...
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Magnesium vs. machined surfaced titanium - osteoblast and osteoclast differentiation

Kwon YD, Lee DW, Hong SO

PURPOSE: This study focused on in vitro cell differentiation and surface characteristics in a magnesium coated titanium surface implanted on using a plasma ion source. MATERIALS AND METHODS: 40 commercially made...
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