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The Clinical Characteristics of Steroid Responsive Nephrotic Syndrome of Children according to the Serum Immunoglobulin E Levels and Cytokines

Youn YS, Lim HH, Lee JH

PURPOSE: The nephrotic syndrome (NS) is characterized by the favorable response to glucocorticoid therapy and the development of NS may be associated with dysfunctional immune systems. In order to investigate...
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Serum IgE Levels in Korean Patients with Human Immunodeficiency Virus Infection

Park JH, Shin BC, Do BH, Oh JT, Lee JM, Kim SW, Kim NS

  • KMID: 1129107
  • Korean J Intern Med.
  • 2002 Jun;17(2):88-93.
BACKGROUND: Human immunodeficiency virus (HIV) infection results in a selective CD4+ T cell depletion and an impairment of T cell regulation. Despite the immune depletion, the progression of HIV infection...
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Sensitization rates of causative allergens for dogs with atopic dermatitis: detection of canine allergen-specific IgE

Kang MH, Kim HJ, Jang HJ, Park HM

Allergen-specific IgE serology tests became commercially available in the 1980s. Since then these tests have been widely used to diagnose and treat allergic skin diseases. However, the relationship between a...
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Measurement of IgE and IgG subclass antibodies to whole body antigen and two major allergens (Der fI & Der fII) of Dermatophagoides farinae in normal subjects and asthmatics

Hong CS, Park JW, Nahm DH

House dust mites have been known as the most important allergen in respiratory allergic diseases. Among several mite allergens, group I and group II antigens were recognized as major allergens....
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Comparison of Specific IgE Antibodies to Wheat Component Allergens in Two Phenotypes of Wheat Allergy

Nam YH, Hwang EK, Jin HJ, Lee JM, Shin YS, Ye YM, Palacin A, Salcedo G, Lee SY, Park HS

Specific IgE to gliadin was proposed as a marker for wheat dependent exercise induced anaphylaxis, while Tri a 14 was found to induce IgE response in baker's asthma. We evaluated...
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Allergic Asthma and Rhinitis Caused by Household Rabbit Exposure: Identification of Serum-Specific IgE and Its Allergens

Choi JH, Kim HM, Park HS

Although rabbits are common domestic pets, severe respiratory allergic reactions to rabbits in households are unusual. Ory c 1, a 17-kDa glycoprotein found in saliva and fur, has previously been...
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Comparison of the ImmunoCAP Assay and AdvanSureâ„¢ AlloScreen Advanced Multiplex Specific IgE Detection Assay

Park KH, Lee J, Lee SC, Son YW, Sim DW, Lee JH, Park JW

PURPOSE: The AdvanSureâ„¢ AlloScreen assay is an advanced multiplex test that allows for simultaneous detection of specific IgE (sIgE) against multiple allergens. For precise identification of causative allergens in allergic...
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Immunologic Evaluation of Immediate Hypersensitivity to Cefaclor

Yoo HS, Kim SH, Kwon HS, Kim TB, Nam YH, Ye YM, Park HS

PURPOSE: Cefaclor is widely prescribed for various infectious diseases. As its consumption increases, the number of hypersensitivity reactions to cefaclor has increased. This study aimed to evaluate the immunologic findings...
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The relationship of stress with serum IgE level in patients with bronchial asthma

Koh KB, Hong CS

The relationship of stress perception and frequency of stressors with serum total Ig E level was investigated in 54 outpatients with bronchial asthma. The GARS (global assessment of recent stress)...
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FCepsilonRI Gene Promoter Polymorphisms and Total IgE Levels in Susceptibility to Atopic Dermatitis in Korea

Park KY, Park MK, Kim EJ, Lee MK, Seo SJ

IgE-dependent activation of mast cells and basophils through the high-affinity IgE receptor (FcepsilonRI) is involved in the pathogenesis of allergen-induced immune responsiveness in atopic diseases like atopic dermatitis (AD). We...
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Paradoxical Increase of IgE Binding Components during Allergen-Specific Immunotherapy in Pollinosis Patients

Kim MA, Yoon MG, Jin HJ, Shin YS, Park HS

Allergen-specific immunotherapy (SIT) reduces allergen specific IgE (sIgE) levels and achieves clinical and immunological tolerance by modulating innate and adaptive immunological responses. Increased temperature and CO2 concentrations caused by climate...
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C3-containing IgE immune complexes in asthmatic patients

Nahm DH, Park HS

Higher levels of IgE-containing immune complexes (IC) have been reported in sera from patients with allergic diseases than in sera from controls. To evaluate the possibility of an IC-mediated mechanism...
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Quantitative measurement of serum allergen-specific IgE on protein chip

Kim TE, Park SW, Cho NY, Choi SY, Yong TS, Nahm BH, Lee S, Noh G

  • KMID: 1081465
  • Exp Mol Med.
  • 2002 May;34(2):152-158.
Type I allergy is an immunoglobulin E (IgE)-mediated hypersensitivity disease inflicting more than quarter of the world population. In order to identify allergen sources, skin provocation test and IgE serology...
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Sensitization of Children to Storage Mites in Kutahya, Turkey

Akdemir C, Soyucen E

Specific IgE against Acarus siro, Glycphagus domesticus, Tyrophagus putrescentiae, and Lepidoglyphus destructor have been investigated by ELISA in sera of 92 children. Of them, 41 were found to be specific...
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Detection of specific serum IgE in clonorchiasis cases and analysis of Clonorchis sinensis allergens

Yong TS, Kim DS, Lee SY, Im KI, Lee KY

Specific serum IgE levels of Clonorchis sinensis in infected humans were measured by avidin-biotin ELISA, and allergens from C. sinensis were identified by immunoblot and autoradiography. Then, allergens fractionated by...
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The Clinical Characteristics of Anisakis Allergy in Korea

Choi SJ, Lee JC, Kim MJ, Hur GY, Shin SY, Park HS

Anisakidae larvae can cause anisakiasis when ingested by humans. Although several groups have reported a gastrointestinal Anisakis allergy among people in Spain and Japan, our report is the first to...
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Putative association of RUNX1 polymorphisms with IgE levels in a Korean population

Chae SC, Park BL, Park CS, Ryu HJ, Yang YS, Lee SO, Choi YH, Kim EM, Uh ST, Kim YH, Kim KK, Oh B, Chung HT, Kimm K, Shin HD

  • KMID: 1098093
  • Exp Mol Med.
  • 2006 Oct;38(5):583-588.
RUNX1, a member of the runt domain gene family of transcription factors, encodes a heterodimeric transcription factor and regulates the expression of various genes related to hematopoiesis and myeloid differentiation....
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A Case of Piperacillin-induced Occupational Anaphylaxis: Detection of Serum IgE to Piperacillin-HSA Conjugate

Kim JE, Kim SH, Kim JH, Bahn JW, Jin HJ, Ye YM, Park HS

This is the first reported detection of serum IgE antibody to piperacillin-human serum albumin (HSA) conjugate in a patient presenting with anaphylaxis that developed after occupational exposure. A 24-yr-old nurse,...
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Current Status of Serum Allergen Tests in Korea

Lim HS, Kim HS, Oh H

BACKGROUND: Due to the westernization of living environments in Korea, a number of allergy patients are greatly increasing. External quality control assessments are difficult for allergy tests due to...
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Detection of Allergen Specific IgE by AdvanSure Allergy Screen Test

Oh EJ, Lee SA, Lim J, Park YJ, Han K, Kim Y

BACKGROUND: In vitro serum allergen-specific IgE tests have been routinely used in the clinical diagnosis of allergic diseases. We evaluated the clinical usefulness of a newly introduced multiple antigen screen...
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