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Anti-Melanogenic Effect from Submerged Mycelial Cultures of Ganoderma weberianum

Lai YJ, Hsu KD, Huang TJ, Hsieh CW, Chan YH, Cheng KC

Compounds from Lingzhi has been demonstrated the ability for inhibiting tyrosinase (a key enzyme in melanogenesis) activity. In this study, we investigated the anti-melanogenic activity from the submerged mycelial culture...
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The Antiproliferation Activity of Ganoderma formosanum Extracts on Prostate Cancer Cells

Chiang CY, Hsu KD, Lin YY, Hsieh CW, Liu JM, Lu TY, Cheng KC

Androgen-independent prostate cancer accounts for mortality in the world. In this study, various extracts of a medical fungus dubbed Ganoderma formosanum were screened for inhibition of DU145 cells, an androgen-independent...
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Enhanced Allergic Inflammation of Der p 2 Affected by Polymorphisms of MD-2 Promoter

Liao EC, Hsieh CW, Chang CY, Yu SJ, Sheu ML, Wu SM, Tsai JJ

PURPOSE: Myeloid differentiation-2 (MD-2) has been associated with endotoxin and inflammatory disorders because it can recognize lipopolysaccharide (LPS) binding and attenuate Toll-like receptor 4 (TLR4)-mediated signaling. However, its role in...
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