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Metronomic oral paclitaxel shows anti-tumor effects in an orthotopic mouse model of ovarian cancer

Hahn HS, Lee KH, Lee IH, Lee JH, Whang CS, Jo YW, Kim TJ

OBJECTIVE: The purpose of this study was to compare the in vivo anti-tumor efficacy of a mucoadhesive, lipid-based, oral paclitaxel formulation (DHP107) with traditional, intraperitoneal (IP) paclitaxel using an orthotopic...
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Comparison of laparoscopy and laparotomy for the management of early-stage ovarian cancer: surgical and oncological outcomes

Koo YJ, Kim JE, Kim YH, Hahn HS, Lee IH, Kim TJ, Lee KH, Shim JU, Lim KT

OBJECTIVE: To investigate the surgical and oncological outcomes of laparoscopic surgery compared with laparotomy for the treatment of early-stage ovarian cancer. METHODS: Data from patients who underwent surgical management for early-stage...
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Selective cyclooxygenase inhibitors increase paclitaxel sensitivity in taxane-resistant ovarian cancer by suppressing P-glycoprotein expression

Lee JP, Hahn HS, Hwang SJ, Choi JY, Park JS, Lee IH, Kim TJ

OBJECTIVE: The purpose of this study was to investigate whether selective cyclooxygenase (COX) inhibitors promote paclitaxel-induced apoptosis in taxane-resistant ovarian cancer cells by suppressing MDR1/P-glycoprotein (P-gp) expression. METHODS: Taxane-resistant ovarian cancer...
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The safety of conization in the management of adenocarcinoma in situ of the uterine cervix

Kim ML, Hahn HS, Lim KT, Lee KH, Kim HS, Hong SR, Kim TJ

OBJECTIVE: To evaluate the occurrence of residual or recurrent disease after conization for adenocarcinoma in situ (AIS) of the uterine cervix. METHODS: Medical records of 99 patients with a histologically diagnosis...
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The clinical approach for endometrial biopsies with atypical endometrial hyperplasia for further management

Hahn HS, Yoon SG, Kim WC, Choi HJ, Lee IH, Kwon YS, Kim TJ, Lim KT, Lee KH, Shim JU, Mok JE

  • KMID: 2273817
  • Korean J Obstet Gynecol.
  • 2009 Dec;52(12):1273-1278.
OBJECTIVE: To evaluate the proper approach in women diagnosed with atypical endometrial hyperplasia (AEH) by endometrial biopsy. METHODS: We retrospectively analyzed the medical records of 108 patients who underwent hysterectomies for...
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Comparison of surgical approach to staging operation for endometrial cancer including pelvic and paraaortic lymphadenectomy

Hahn HS, Yoon SG, Kim WC, Choi HJ, Lee IH, Kwon YS, Kim TJ, Lim KT, Lee KH, Shim JU, Mok JE

  • KMID: 2273760
  • Korean J Obstet Gynecol.
  • 2009 Sep;52(9):920-927.
OBJECTIVE: To compare laparoscopic surgery with laparotomy in comprehensive surgical staging of endometrial cancer. METHODS: We retrospectively analyzed the medical records of 272 patients with endometrial adenocarcinoma treated by staging operation...
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Clinicopathologic study of ovarian granulosa cell tumors

Lee IH, Kwon YS, Hahn HS, Yoon SG, Hong JS, Kim TJ, Lee KH, Shim JU, Mok JE, Lim KT

  • KMID: 2273704
  • Korean J Obstet Gynecol.
  • 2009 Apr;52(4):429-436.
OBJECTIVE: The aim of this study was to evaluate the clinicopathologic characteristics of granulosa cell tumor of the ovary (OGCT). METHODS: We retrospectively reviewed the medical records of 27 patients with...
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Fertility preservation in patients with early epithelial ovarian cancer

Kwon YS, Hahn HS, Kim TJ, Lee IH, Lim KT, Lee KH, Shim JU, Mok JE

OBJECTIVE: To assess the role of fertility preservation in the treatment of patients with early epithelial ovarian cancer (EOC). METHODS: We retrospectively analyzed the medical records of 21 patients with early...
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COH-IVF Outcomes for Infertile Patients With Borderline Ovarian Tumor After Conservative Treatment

Lee HJ, Ahn KY, Hahn HS, Park CW, Yang KM, Lee IH, Kim TJ, Lim KT, Lee KH, Kang IS

  • KMID: 2288275
  • Korean J Reprod Med.
  • 2007 Jun;34(2):87-94.
OBJECTIVE: To examine determinants of successful pregnancy and evaluate COH-IVF outcomes of infertile patients after conservative surgical treatment of borderline ovarian tumor (BOT). METHODS: In women of BOT (n=93), from January...
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Three different approach to hysterectomy for benign uterine pathology

Hahn HS, Choi KH, Kim JM, Lee HJ, Choi NM, Yoo WS, Kim KY, Kim NS, Jo SH, Hong JS

  • KMID: 2273133
  • Korean J Obstet Gynecol.
  • 2007 May;50(5):769-775.
OBJECTIVE: To evaluate the rates and clinical outcomes between abdominal hysterectomy (AH), laparoscopic hysterectomy (LH) and vaginal hysterectomy (VH). METHODS: Medical records of 236 patients who underwent hysterectomy (by one...
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Effects of Y Chromosome Microdeletion on the Outcome of in vitro Fertilization

Choi NM, Yang KM, Kang IS, Seo JT, Song IO, Park CW, Lee HS, Lee HJ, Ahn KY, Hahn HS, Lee HJ, Kim NY, Yu SY

  • KMID: 2235780
  • Korean J Fertil Steril.
  • 2007 Mar;34(1):41-48.
OBJECTIVE: To determine whether the presence of Y-chromosome microdeletion affects the outcome of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) program. METHODS: Fourteen couples with microdeletion in azoospermic factor...
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A Case Intestinal Mucormycosis Healing of Ulcer after Only Amphotericin B Treatment

Hahn HS, Jung HS, Song SH, Lim DY, Kyung SY, Hwang JK, Chung MG, Koo YS, Kim YK, Kim JH, Park DK, Cho HY

  • KMID: 1930000
  • Korean J Gastrointest Endosc.
  • 2002 Jul;25(1):43-47.
Mucormycosis is an uncommon, frequently fatal, opportunistic fungal infection and usually occur in immunocompromised patients. Rhinocerebral and pulmonary disease are the common forms but intestinal infection is an extremely rare...
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Two Cases of Microscopic Polyangiitis with Honeycomb Lung

Hahn HS, Hwang JK, Jung HS, Song SH, Joo KW, Park GY, Lee JH, Oh YH, Lee HJ

  • KMID: 2318387
  • Tuberc Respir Dis.
  • 2002 May;52(5):550-556.
Microscopic polyangiitis is a systemic small-vessel vasculitis that is associated primarily with necrotizing glomerulonephritis and pulmonary capillaritis. A recurrent and diffuse alveolar hemorrhage due to pulmonary capi llaritis is the...
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The Relationship of Serum Angiotensin Converting Enzyme (ACE), Angiotensin II and Clinical Markers in the Idiopathic Interstitial Pneumonia

Kyung SY, Hahn HS, Song SH, Hwang JK, Lim YH, An CH, Park GY, Park JW, Jeong SH, Ha SY, Lee JW

  • KMID: 2318382
  • Tuberc Respir Dis.
  • 2002 May;52(5):506-518.
BACKGROUND: There have been several studies showing that angiotensin II and the angiotensin convertingenzyme (ACE) contribute to the activation of fibroblast including the pulmonary fibrosis, and apoptosis of the al...
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A Case of Acquired Amegakaryocytic Thrombocytopenia Responding to Immunosuppressive Therapy

Hwang YH, Bang SM, Hahn HS, Ahn JY, Cho EK, Shin DB, Lee JH

  • KMID: 2083444
  • Korean J Hematol.
  • 2002 May;37(2):147-152.
Acquired amegakaryocytic thrombocytopenia is a relatively rare bone marrow failure disorder characterized by severe thrombocytopenia associated with a total absence or a marked reduction in the number of bone marrow...
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A Study of Clinical Investigations of Pulmonary Tuberculoma

Song SH, Hahn HS, Kyung SY, Hwang JK, An CH, Lim YH, Park GY, Park JW, Jeong SH

  • KMID: 2318365
  • Tuberc Respir Dis.
  • 2002 Apr;52(4):330-337.
BACKGROUND: A pulmonary tuberculoma is one of the most common causes of a solitary pulmonary lesion. Treating a tuberculoma is still controversial and there are few reports on antituberculosis chemotherapy....
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A Case of Adrenocortical Adenoma Causing Cushing's Syndrome with Contralateral Nonfunctioning Adenoma

Kyung SY, Hahn HS, Yoon HJ, Hwang YH, Seo CJ, Jeong YS, Kim HK, Park HY, Kim HS, Lee JN, Ha SY, Kang MH

  • KMID: 2199947
  • J Korean Soc Endocrinol.
  • 2002 Apr;17(2):286-291.
We report the case of a 43-year-old woman with Cushing's syndrome showing bilateral adrenococortical adenomas. We performed bilateral selective adrenal vein samplings. Hypersecretion of cortisol on the left sided adrenal...
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The Practice and Evaluation of Problem-Based Learning in College of Medicine, Chungbuk National University

Chung IW, Shin CJ, Hahn HS, Song YJ

  • KMID: 2306941
  • Korean J Med Educ.
  • 1999 Nov;11(2):285-295.
Problem-based learning(PBL), introduced to medical education committee of Chungbuk National University in 1996, was firstly implemented as a regular course of medical education only with 0.5 credit in 1998. Tutorials of...
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Correlation between Helicobacter pylori Infection and Lymphoid Follicle Formation in Gastrectomy Specimens

Lee WA, Hahn HS, Kim WH, Kim YI

  • KMID: 1921801
  • Korean J Pathol.
  • 1998 Mar;32(3):162-168.
Histopathologic studies for Helicobacter pylori (H. pylori)-associated chronic gastritis have been mostly undertaken with endoscopic biopsy specimens, often leading to an inappropriate evaluation of the gastric mucosal alterations. The purpose...
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Cytomegalovirus Infection in Idiopathic Inflammatory Bowel Disease: Clinicopathologic Analysis of 6 Cases

Lee WA, Hahn HS, Kim WH, Kim YI

  • KMID: 1921817
  • Korean J Pathol.
  • 1998 Feb;32(2):125-130.
Cytomegalovirus (CMV) infection is an uncommon association with idiopathic inflammatory bowel disease (IBD) often leading to a variety of serious complications. A total of 41 resected cases of IBD were...
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