J Korean Soc Endocrinol.  2002 Apr;17(2):286-291.

A Case of Adrenocortical Adenoma Causing Cushing's Syndrome with Contralateral Nonfunctioning Adenoma

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Gachon Medical School, Gil Medical Center, Incheon, Korea.
  • 2Department of Radiology, Gachon Medical School, Gil Medical Center, Incheon, Korea.
  • 3Department of General Surgery, Gachon Medical School, Gil Medical Center, Incheon, Korea.
  • 4Department of Anatomical Pathology, Gachon Medical School, Gil Medical Center, Incheon, Korea.

Abstract

We report the case of a 43-year-old woman with Cushing's syndrome showing bilateral adrenococortical adenomas. We performed bilateral selective adrenal vein samplings. Hypersecretion of cortisol on the left sided adrenal tumor was observed, but no evidence of cortisol hypersecretion from the adrenal tumor on the right side was observed. The left adrenal tumor was resected selectively, but the right adrenal gland was reserved. The left adrenal tumor was histologically diagnosed as a adrenal adenoma without any evidence of nodular hyperplasia. Following the resection of the left adrenal gland, no cortisol hypersecretion from the remaining adrenal tumor on the right side was observed until now, suggesting that a selective adrenalectomy of functioning adenoma may be an acceptable treatment modality.


MeSH Terms

Adenoma*
Adrenal Glands
Adrenalectomy
Adrenocortical Adenoma*
Adult
Cushing Syndrome*
Female
Humans
Hydrocortisone
Hyperplasia
Veins
Hydrocortisone
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