- Injections for nutrition and cosmetic purposes: promoted effect vs. objective evidence
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Shin HY
- KMID: 2393521
- J Korean Med Assoc.
- 2017 Oct;60(10):784-788.
- doi: 10.5124/jkma.2017.60.10.784
The introduction of intravenous nutritional therapy for cosmetic and health purposes in Korea has been controversial. Because it brings ethical problems of off-label prescribing on the basis of low level... -
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- A Case of Licorice-Induced Hypokalemic Rhabdomyolysis in a Patient Using a Diuretic Drug
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Park KA, Seok SJ, Kim SJ, Gil HW, Yang JO, Lee EY, Hong SY
- KMID: 2258900
- Korean J Med.
- 2011 Jun;80(Suppl 2):S258-S262.
Glycyrrhizic acid is a component of licorice. It can cause hypokalemia through the inhibition of 11beta-hydroxysteroid dehydrogenase. The severity of symptoms depends on the dose and duration of licorice intake,... -
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- Licorice Induced Hypokalemia
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Cho S, Lim B, Cho H, Joung J, Choi Y, Kim D, Shin G, Kim H
- KMID: 2079205
- Korean J Nephrol.
- 2001 Nov;20(6):1021-1025.
A high intake of licorice can cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure and depression of renin-angiotensin-aldosterone system. Glycyrrhizic acid, a component of licorice, produces... -
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- A Case of Licorice Induced Hypokalemic Paralysis with Rhabdomyolysis
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Hong HI, Han KH, Hwang JW, Kim YD, Shim MS, Kim JY
- KMID: 2331200
- J Korean Soc Endocrinol.
- 2005 Apr;20(2):179-182.
Prolonged ingestion of licorice can cause hypermineralocorticoidism, with sodium retention, potassium loss and hypertension. Nevertheless, its initial presentation with a very severe degree of hypokalemic paralysis and rhabdomyolysis are exceedingly... -
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- Quantitative Analysis of Eleven Bioactive Constituents of a Traditional Herbal Medicine, Yeonggyechulgam-tang using, Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry
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Seo CS, Shin HK
- KMID: 2387056
- Nat Prod Sci.
- 2017 Jun;23(2):84-91.
- doi: 10.20307/nps.2017.23.2.84
This study proposes a sensitive and selective liquid chromatography-electrospray ionization tandem mass spectrometry method of efficiently assessing the quality of a traditional herbal medicine called Yeonggyechulgam-tang (YGCGT). The following compounds... -
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- Antiplaque and antigingivitis effects of a mouthrinse containing cetylpyridinium chloride, triclosan and dipotassium glycyrrhizinate
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Shim JY, Yim SB, Chung JH, Hong KS
- KMID: 2027784
- J Periodontal Implant Sci.
- 2012 Apr;42(2):33-38.
- doi: 10.5051/jpis.2012.42.2.33
PURPOSE: The goal of this study was to evaluate the clinical anitplaque and antigingivitis effects of a mouthrinse containing cetylpyridinium chloride (CPC), triclosan and dipotassium glycyrrhizinate (DPZ) in patients with... -
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- Effect of Glycyrrhizin on Rainbow Trout Oncorhynchus mykiss Leukocyte Responses
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Kim KJ, Jang SI, Marsden MJ, Secombes C, Choi MS, Kim YG, Chung HT
- KMID: 1551640
- J Korean Soc Microbiol.
- 1998 Jun;33(3):263-271.
Treatment of rainbow trout macrophages with glycyrrhizin (GL), an aqueous extract of licorice (Glycyrrhiza glabra), enhanced their respiratory burst activity. Maximal effects were seen using concentrations of 10-100 ug/ml. GL... -
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- Glycyrrhizin Attenuates Kainic Acid-Induced Neuronal Cell Death in the Mouse Hippocampus
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Luo L, Jin Y, Kim ID, Lee JK
- KMID: 1427108
- Exp Neurobiol.
- 2013 Jun;22(2):107-115.
- doi: 10.5607/en.2013.22.2.107
Glycyrrhizin (GL), a triterpene that is present in the roots and rhizomes of licorice (Glycyrrhiza glabra), has been reported to have anti-inflammatory and anti-viral effects. Recently, we demonstrated that GL... -
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- A Case of Glycyrrhizin (Licorice)-induced Hypokalemic Myopathy
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Kim BJ, Hong YH, Sung JJ, Park KS, Hyun CL, Choe G, Park SH, Lee KW
- KMID: 2343238
- J Korean Neurol Assoc.
- 2006 Aug;24(4):389-391.
Glycyrrhizin, the main ingredient of licorice, may evoke severe hypokalemia and muscle paralysis by its mineralocorticoid effects. We present a 78-year-old man who developed subacute flaccid quadriparesis with a high... -
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- Glycyrrhizin Attenuates MPTP Neurotoxicity in Mouse and MPP+-Induced Cell Death in PC12 Cells
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Kim YJ, Lee CS
- KMID: 1486145
- Korean J Physiol Pharmacol.
- 2008 Apr;12(2):65-71.
- doi: 10.4196/kjpp.2008.12.2.65
The present study examined the inhibitory effect of licorice compounds glycyrrhizin and a metabolite 18 beta-lycyrrhetinic acid on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse and on the 1-methyl-4-phenylpyridinium... -
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- Simultaneous Determination of 11 Marker Compounds in Gumiganghwal-tang by HPLC-DAD and LC-MS
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Weon JB, Jung YS, Ryu G, Yang WS, Ma CJ
- KMID: 2366690
- Nat Prod Sci.
- 2016 Dec;22(4):238-245.
- doi: 10.20307/nps.2016.22.4.238
Gumiganghwal-tang has been used for the treatment of common cold for a long-time. We developed an accurate and sensitive high performance liquid chromatography-diode array detection (HPLC-DAD) and electrospray ionization mass... -
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- The use of Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, in robust neuroprotection in the postischemic brain
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Kim SW, Lim CM, Lee HK, Lee JK
- KMID: 1447444
- Anat Cell Biol.
- 2011 Dec;44(4):304-313.
- doi: 10.5115/acb.2011.44.4.304
Stronger Neo-Minophagen C (SNMC) is a glycyrrhizin-containing preparation that is approved in Japan for the treatment of chronic hepatic diseases and is marketed in Japan, China, Korea, Taiwan, and India.... -
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- Qualitative and Quantitative Analysis of Thirteen Marker Components in Traditional Korean Formula, Samryeongbaekchul-san using an Ultra-Performance Liquid Chromatography Equipped with Electrospray Ionization Tandem Mass Spectrometry
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Seo CS, Shin HK
- KMID: 2328873
- Nat Prod Sci.
- 2016 Jun;22(2):93-101.
- doi: 10.20307/nps.2016.22.2.93
For efficient quality control of the Samryeongbaekchul-san decoction, a powerful and accurate an ultra-performance liquid chromatography (UPLC) coupled with electrospray ionization (ESI) tandem mass spectrometry (MS) method was developed for... -
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- Glycyrrhizin and Morroniside Stimulate Mucin Secretion from Cultured Airway Epithelial Cells
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Heo HJ, Lee HJ, Kim C, Son KH, Kim YC, Kim YS, Kang SS, Park YC, Kim YH, Seo UK, Seok JH, Lee CJ
- KMID: 1587471
- Korean J Physiol Pharmacol.
- 2006 Dec;10(6):317-321.
In this study, we investigated whether glycyrrhizin, prunetin and morroniside affect mucin secretion from cultured airway epithelial cells and compared the possible activities of these agents with the inhibitory action... -
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- Increase in the Level of Proinflammatory Cytokine HMGB1 in Nasal Fluids of Patients With Rhinitis and its Sequestration by Glycyrrhizin Induces Eosinophil Cell Death
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Cavone L, Cuppari C, Manti S, Grasso L, Arrigo T, Calamai L, Salpietro , Chiarugi A
- KMID: 2360782
- Clin Exp Otorhinolaryngol.
- 2015 Jun;8(2):123-128.
- doi: 10.3342/ceo.2015.8.2.123
OBJECTIVES: The nuclear protein high mobility group protein box 1 (HMGB1) is a proinflammatory mediator that belongs to the alarmin family of proinflammatory mediators, and it has recently emerged as... -
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- Effect of glycyrrhizin on nicotine-induced behavioral disturbance of planarian, Dugesia japonica
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Kim YJ, So J, Yi YJ, Lee SM
- KMID: 2452873
- J Biomed Transl Res.
- 2019 Jun;20(2):21-29.
- doi: 10.12729/jbtr.2019.20.2.021
Nicotine is a component of tobacco products and is one of the most commonly abused substances that leads to addiction. Therefore, the present study was performed to investigate the behavioral... -
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- A Clinical Study of the Effect of Periodontitis-Medical Gel on Human Gingivitis and Periodontitis
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Chai JK, Choi JS, Park JS, Suh JG, Choi SH, Cho KS, Kim CK
- KMID: 2321543
- J Korean Acad Periodontol.
- 2000 Mar;30(1):11-25.
The purpose of this study was to evaluate the clinical effects of Dipotassium glycyrrhizinate, Allantoin, Hinokitiol, Cetylpyridinium chloride containing gel(Dentheth(R)) on periodontitis. 41 patients with sites having pocket depth of... -
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- Stimulation of melanogenesis by glycyrrhizin in B16 melanoma cells
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Jung GD, Yang JY, Song ES, Park JW
- KMID: 938876
- Exp Mol Med.
- 2001 Sep;33(3):131-135.
Glycyrrhizin (GR), triterpenoid saponin composed of one glycyrrhetinic acid (GA) and two glucuronic acids, is a main constituent of the hydrophilic fraction of licorice (Glycyrrhiza glabra) extracts and is known... -
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- Inhibition of Oxidative Tissue Damage and Mitochondrial Dysfunction by Glycyrrhizin in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease
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Park SE, Hong KM, Han JH, Kim DE, Lee CS
- KMID: 2343255
- J Korean Neurol Assoc.
- 2007 Aug;25(3):353-363.
BACKGROUND: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) produces an irreversible and severe parkinsonian-like syndrome. A licorice compound glycyrrhizin exerts a cytoprotective or anti-oxidant effect in various disease conditions, but its effect against the MPTP-induced... -
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- Anti-carcinogenic effects of non-polar components containing licochalcone A in roasted licorice root
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Park SY, Kim EJ, Choi HJ, Seon MR, Lim SS, Kang YH, Choi MS, Lee KW, Yoon Park
- KMID: 2313737
- Nutr Res Pract.
- 2014 Jun;8(3):257-266.
BACKGROUND/OBJECTIVE: Licorice has been shown to possess cancer chemopreventive effects. However, glycyrrhizin, a major component in licorice, was found to interfere with steroid metabolism and cause edema and hypertension. The... -
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