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The effects of electroconvulsive shock on glutamate decarboxylase and glutamine synthetase activity in adrenalectomized rat hippocampus

Joo YH, Kim HL, Kim YS

  • KMID: 1692248
  • J Korean Neuropsychiatr Assoc.
  • 1992 Jul;31(4):672-680.
No abstract available.
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Stiff-man Syndrome: A case report

Choi HY, Sung DH

  • KMID: 2324526
  • J Korean Acad Rehabil Med.
  • 2007 Apr;31(2):232-237.
The stiff-man syndrome is a rare and disabling disorder, characterized by muscle rigidity with superimposed painful spasms involving axial and limb musculature. The clinical symptoms are continuous contraction of agonist...
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Ethanol Extract of Perillae Herba Enhances Pentobarbital-Induced Sleep and Non-Rapid Eye Movement (NREM) Sleep through GABA(A)-ergic Systems

Kwon YO, Ha TW, Oh KW

Perillae Herba has been traditionally used for the sedation in the oriental countries. Therefore, this study was conducted to determine whether Perillae Herba ethanol extract (PHEE) enhances pentobarbital-induced sleeping behaviors...
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Clinical Courses of Two Women with Gestational Diabetes Mellitus Who are GAD Antibody Positive

Yu SH, Song MJ, Kim SH, Yim CH, Han KO, Park WK, Yoon HK, Chung HY

Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees with onset or first recognition during pregnancy. Women with GDM are at high risk of developing type 2...
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Analysis of the Persistence of Islet Cell Cytoplasmic Antibodies and Glutamic Acid Decarboxylase ( GAD ) 65 Antibodies in Type 1 Diabetic Children

Lee HW, Won KC

  • KMID: 2178008
  • J Korean Diabetes Assoc.
  • 1998 Jun;22(2):145-154.
BACKGROUND: Type 1 diabetes mellitus is attributable to progressive autoimmune destruction of insulin-producing pancreatic islet cells, which result in absolute deficiency of insulin. Serum antibodies against islet antigens in patients...
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Polymeric Gene Delivery for Diabetic Treatment

Kim SW

Several polymers were used to delivery genes to diabetic animals. Polyaminobutyl glycolic acid was utilized to deliver IL-10 plasmid DNA to prevent autoimmune insulitis of non-obese diabetic (NOD) mouse. Polyethylene...
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Chronic Complications in Adult Diabetic Patients with and without GAD Antibody

Chung JO, Cho DH, Chung DJ, Chung MY

BACKGROUND: Although the majority of diabetes mellitus (DM) patients diagnosed as adults have non-autoimmune forms of the disease, islet autoimmunity is encountered in some patients initially thought to have type...
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Concurrence of Diabetic Ketoacidosis and Acute Ischemic Stroke due to Moyamoya Disease

Lee H, Lee J, Kim S, Oh MS, Han KH, Kang KS, Kim S

Although the etiology of moyamoya disease (MMD) remains unknown, autoimmunity is one of the proposed pathogeneses. Unlike other autoimmune disorders that are associated with cerebral arteritis, concurrence of MMD and...
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Prevalence and Clinical Characteristics of Recently Diagnosed Type 2 Diabetes Patients with Positive Anti-Glutamic Acid Decarboxylase Antibody

Hwangbo Y, Kim JT, Kim EK, Khang AR, Oh TJ, Jang HC, Park KS, Kim SY, Lee HK, Cho YM

BACKGROUND: Latent autoimmune diabetes in adults (LADA) refers to a specific type of diabetes characterized by adult onset, presence of islet auto-antibodies, insulin independence at the time of diagnosis, and...
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A case of fulminant type 1 diabetes mellitus

Rhee SY, Chon S, Koh G, Oh S, Woo JT, Kim JW, Kim YS

  • KMID: 2252420
  • Korean J Med.
  • 2006 Mar;70(3):342-346.
A novel subtype of type 1B diabetes with rapid onset and no evidence of autoimmunity has been recently proposed as fulminant type 1 diabetes. The pathogenesis of fulminant type 1...
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A Case of Fulminant Type 1 Diabetes Mellitus in an Elderly Patient

Woo SM, Hong SH, Lee SY, Lee SH, Lee DK, Yang SJ

Insulin deficiency due to destruction of pancreatic beta-cells is a typical characteristic of type 1 diabetes mellitus (DM). In 2000 Imagawa proposed a novel diagnostic model defining "fulminant type 1...
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A Case of Fulminant Type 1 Diabetes Associated with Pregnancy

Yu HK, Nam M, Shim WS, Chung HJ, Kim EJ, Hong SB, Kim YS

Type 1 diabetes is characterized by insulin deficiency due to destruction of pancreatic beta-cells. A novel subtype of type 1B which is rapidly developed without any evidence of autoimmunity has...
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Comparison of the prevalence of islet autoantibodies according to age and disease duration in patients with type 1 diabetes mellitus

Kong YH, Kim MS, Lee DY

PURPOSE: This study investigated the prevalence of islet autoantibodies in children and adults with T1DM according to their age and the duration of disease. METHODS: We measured the levels of islet...
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Frequency of Diabetes and Thyroid Autoantibodies in Patients with Type 1 Diabetes and Their Siblings

Oh KY, Kim YH, Yang EM, Kim CJ

The aim of this study was to better understand the frequency of autoimmune thyroid and diabetes antibodies in patients with type 1 diabetes mellitus (T1DM) compared with their siblings. Glutamic...
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Long-term prenatal stress increases susceptibility of N-methyl-D-aspartic acid-induced spasms in infant rats

Kwon HH, Lee T, Hong J, Kim DW, Kang JW

PURPOSE: Infantile spasms, also known as West syndrome, is an age-specific epileptic seizure. Most patients with this condition also exhibit delayed development. This study aimed to determine the effect of...
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In Silico Model-driven Assessment of the Effects of Brain-derived Neurotrophic Factor Deficiency on Glutamate and Gamma-Aminobutyric Acid: Implications for Understanding Schizophrenia Pathophysiology

Agrawal R, Kalmady SV, Venkatasubramanian G

OBJECTIVE: Deficient brain-derived neurotrophic factor (BDNF) is one of the important mechanisms underlying the neuroplasticity abnormalities in schizophrenia. Aberration in BDNF signaling pathways directly or circuitously influences neurotransmitters like glutamate...
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Rosmarinic Acid Potentiates Pentobarbital-Induced Sleep Behaviors and Non-Rapid Eye Movement (NREM) Sleep through the Activation of GABA(A)-ergic Systems

Kwon YO, Hong JT, Oh KW

It has been known that RA, one of major constituents of Perilla frutescens which has been used as a traditional folk remedy for sedation in oriental countries, shows the anxiolytic-like...
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Prevalence of autoimmune thyroiditis in patients with type 1 diabetes: a long-term follow-up study

Hwang GB, Yoon JS, Park KJ, Lee HS, Hwang JS

PURPOSE: Type 1 diabetes mellitus (DM) is associated with autoimmune diseases such as thyroiditis. Therefore, we aimed to investigate the prevalence of autoimmune thyroiditis in patients with type 1 DM. METHODS:...
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Measurement of Pancreatic Islet Cell Autoantibodies by ELISA and RIA in Patients with Diabetes Mellitus

Song JW, Kim KR, Nam SY, Kim DH, Lee A, Kim MH, Song KS, Kim HS

  • KMID: 2146113
  • Korean J Clin Pathol.
  • 2001 Oct;21(5):396-402.
BACKGROUND: The isoenzyme of glutamate decarboxylase (GAD), islet associated antigen (IA2, IAA) and insulin are known to be the major target antigens of pancreatic islet cell autoantibody as a predictor...
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Thyroid autoimmunity in children and adolescents with newly diagnosed type 1 diabetes mellitus

Jung ES, Han DK, Yang EM, Kim MS, Lee DY, Kim CJ

PURPOSE: This study aim to investigate the occurrence of autoimmune thyroid disease in children and adolescents at onset of type 1 diabetes mellitus (T1DM) and to assess whether the presence...
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