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Effects of cyclic nucleotides and glipizide on the cardiovascular response of baclofen in the rats

Shin IC, Koh HC, Ha JH

  • KMID: 2285182
  • Korean J Physiol Pharmacol.
  • 1997 Dec;1(6):647-655.
The purpose of present study is to investigate the influence of a spinal gamma-aminobutyric acid B(GABA|B) receptor on a central regulation of blood pressure (BP) and heart rate (HR), and to define its...
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Effects of Sulfonylureas on Peroxisome Proliferator-Activated Receptor gamma Activity and on Glucose Uptake by Thiazolidinediones

Lee KW, Ku YH, Kim M, Ahn BY, Chung SS, Park KS

BACKGROUND: Sulfonylurea primarily stimulates insulin secretion by binding to its receptor on the pancreatic beta-cells. Recent studies have suggested that sulfonylureas induce insulin sensitivity through peroxisome proliferator-activated receptor gamma (PPARgamma),...
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The Inhibitory Effect of the Second Generation Sulfonylurea Drugs on Cytochrome P450-catalyzed Reaction by Human Liver Microsomes

Choi JY, Kim SY, Kim KA, Park JY

  • KMID: 2199993
  • J Korean Soc Endocrinol.
  • 2002 Aug;17(4):544-553.
BACKGROUND: Sulfonylurea drugs have been used for many decades as one of the main families of drugs for the treatment of type 2 diabetes mellitus. Even though there are many...
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Effect of Sulfonylureas Administered Centrally on the Blood Glucose Level in Immobilization Stress Model

Sharma N, Sim YB, Park SH, Lim SM, Kim SS, Jung JS, Hong JS, Suh HW

Sulfonylureas are widely used as an antidiabetic drug. In the present study, the effects of sulfonylurea administered supraspinally on immobilization stress-induced blood glucose level were studied in ICR mice. Mice...
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Concurrent Use of Sulfonylureas and Antimicrobials of the Elderly in Korea: A Potential Risk of Hypoglycemia

Lee S, Ock M, Kim H

BACKGROUND: Previous studies have noted that the simultaneous use of sulfonylureas and antimicrobials, which is common, could increase the risk of hypoglycemia. In particular, an age of 65 years or...
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The Mechanism on the Glutamate-evoked Release of [3H) norepinephrine in Rat Cortex Slices

Shin BS, Song DW, Lee SH, Seo MW, Kim YH

  • KMID: 2066064
  • J Korean Neurol Assoc.
  • 1996 Mar;14(1):238-250.
Glutamate Is the predominant excitatory neurotransmitter in the mammalian CNS. To elucidate the influence of glutamate on the noradrenergic neurotransmission in rat cortex, we examined the effects of agents that...
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