- Effect of ginsenosides in a mouse model of bone cancer pain
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Yoon MH, Lee HG, Kim WM, Ju J, Kim YO, Cui JH
- KMID: 1803583
- Anesth Pain Med.
- 2010 Oct;5(4):321-324.
BACKGROUND: Ginsenosides have been used for a long time as an oriental folk medicine. Although ginsenosides modulate the nociceptive transmission, the effect of ginsenosides on a bone cancer pain has... -
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- Effect of Intrathecal Ginsenosides on Mechanical Allodynia in a Neuropathic Rat Model
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Yoon MH, Lee HK, Kim WM, Park JH, Kim YO, Huang LJ
- KMID: 2263303
- Anesth Pain Med.
- 2008 Jul;3(3):205-209.
BACKGROUND: Traditionally, ginseng has been widely used to manage various types of diseases. In particular, the analgesic effect of ginsenosides has been reported for inflammatory pain. However, the effect of... -
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- Effects of Ginsenosides on Relaxation of Rabbit Vaginal Smooth Muscle
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Park K, Kim GS, Kim SO, Kim DS, Kim MK, Park JK, Nah SY, Kim KK
- KMID: 2298679
- Korean J Androl.
- 2003 Aug;21(2):98-102.
PURPOSE: Ginseng has been used throughout the Far East, including Korea and China, as a tonic and restorative agent to maintain physical vitality. The main pharmacoactive molecules of ginseng are... -
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- The role of spinal adrenergic receptors on the antinociception of ginsenosides in a rat postoperative pain model
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Kim IJ, Park CH, Lee SH, Yoon MH
- KMID: 1828069
- Korean J Anesthesiol.
- 2013 Jul;65(1):55-60.
- doi: 10.4097/kjae.2013.65.1.55
BACKGROUND: The effect of spinal adrenergic and cholinergic receptors on the anti-nociceptive effect of intrathecal ginsenosides was determined in a rat postoperative pain model. METHODS: Catheters were placed into the intrathecal... -
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- Analgesic Effect of Intrathecal Ginsenosides in a Murine Bone Cancer Pain
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Yoon MH, Kim WM, Lee HG, Choi JI, Kim YO, Song JA
- KMID: 1454705
- Korean J Pain.
- 2010 Dec;23(4):230-235.
- doi: 10.3344/kjp.2010.23.4.230
BACKGROUND: Bone cancer pain has a disruptive effect on the cancer patient's quality of life. Although ginsenosides have been used as traditional medicine in Eastern Medicine, the effect on bone... -
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- The Effect of Treatment with Intrathecal Ginsenosides in a Rat Model of Postoperative Pain
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Shin DJ, Yoon MH, Lee HG, Kim WM, Park BY, Kim YO, Huang LJ, Cui JH
- KMID: 2278048
- Korean J Pain.
- 2007 Dec;20(2):100-105.
- doi: 10.3344/kjp.2007.20.2.100
BACKGROUND: Ginseng has been used to manage various types of pain in folk medicine. This study characterized the effect of treatment with intrathecal ginsenosides, the active components of ginseng in... -
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- Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test
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Park CH, Kim PN, Lee SH, Yoon MH
- KMID: 1798229
- Korean J Anesthesiol.
- 2013 Feb;64(2):152-160.
- doi: 10.4097/kjae.2013.64.2.152
BACKGROUND: The authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the... -
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- Effect of Ginsenosides on the Lipid Distribution in Rat Tissues
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Kim JY, Kim KS, Seo YY, Song DU, Jung YD, Ahn BW, Yang SY
- KMID: 2048568
- Chonnam Med J.
- 1998 Dec;34(2):255-265.
The effect of total ginsenosides on the composition and peroxidation of lipids in sera and biomembranes of rats fed high cholesterol diet was studied. Male Wistar rats were divided into... -
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- Effect of ginsenosides on the desflurane modulation in the recombinant serotonin type 3A receptor expressed in Xenopus laevis oocytes
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Choi SH, Kim MK, Koo BN, Min KT
- KMID: 2092201
- Korean J Anesthesiol.
- 2009 Jun;56(6):681-686.
- doi: 10.4097/kjae.2009.56.6.681
BACKGROUND: Postoperative nausea and vomiting (PONV) is the most frequent and discomforting side effect following general anesthesia. Most volatile anesthetics have a potent effect on serotonin (5-hydroxydtryptamine, 5-HT) type 3... -
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- Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells
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Jin Y, Baek N, Back S, Myung CS, Heo KS
- KMID: 2452068
- J Bacteriol Virol.
- 2018 Dec;48(4):156-165.
- doi: 10.4167/jbv.2018.48.4.156
Minor ginsenosides Rh1 and Rg2 were isolated from Korean red ginseng and reported to have various biological effects on anti-inflammatory and anti-stress activities. However, the effects of Rh1 and Rg2... -
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- Quantitative Analysis of Dammarane-type Ginsenosides in Different Ginseng Products
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Lee DG, Quilantang NG, Lee JS, Geraldino , Kim HY, Lee S
- KMID: 2432416
- Nat Prod Sci.
- 2018 Dec;24(4):229-234.
- doi: 10.20307/nps.2018.24.4.229
Ginseng products available in different forms and preparations are reported to have varied bioactivities and chemical compositions. In our previous study, four new dammarane-type ginsenosides were isolated from Panax ginseng,... -
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- Inhibition of TNF-alpha-Mediated NF-kappaB Transcriptional Activity by Dammarane-Type Ginsenosides from Steamed Flower Buds of Panax ginseng in HepG2 and SK-Hep1 Cells
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Cho K, Song SB, Tung NH, Kim KE, Kim YH
- KMID: 2048331
- Biomol Ther.
- 2014 Jan;22(1):55-61.
Panax ginseng is a medicinal herb that is used worldwide. Its medicinal effects are primarily attributable to ginsenosides located in the root, leaf, seed, and flower. The flower buds of... -
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- Proapoptotic Ginsenosides Compound K and Rh2 Enhance Fas-induced Cell Death of Human Astrocytoma Cells Through Distinct Apoptotic Signaling Pathways
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Choi K, Choi C
- KMID: 2165995
- Cancer Res Treat.
- 2009 Mar;41(1):36-44.
PURPOSE: Malignant astrocytomas are among the commonest primary brain tumors and they have a grave prognosis, and so there is an urgent need to develop effective treatment. In this study,... -
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- Identification of Dammarane-type Triterpenoid Saponins from the Root of Panax ginseng
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Lee DG, Lee J, Yang S, Kim KT, Lee S
- KMID: 2312882
- Nat Prod Sci.
- 2015 Jun;21(2):111-121.
- doi: 10.0000/nps.2015.21.2.111
The root of Panax ginseng, is a Korea traditional medicine, which is used in both raw and processed forms due to their different pharmacological activities. As part of a continued... -
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- Effects of Triterpenoid Glycosides from Fresh Ginseng Berry on SW480 Human Colorectal Cancer Cell Line
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Xie JT, Du GJ, McEntee E, Aung HH, He H, Mehendale , Wang CZ, Yuan CS
- KMID: 1804675
- Cancer Res Treat.
- 2011 Mar;43(1):49-55.
PURPOSE: The pharmacological activities, notably the anticancer properties, of bioactive constituents fromfresh American ginseng berry have not yet been well studied. In this study, we investigated the antiproliferative effects of... -
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- Protective Effect of Ginsenoside Rb1 and Rg1 Against beta Amyloid ( 25-35 )-Induced Neurotoxicity on B103 cells
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Lee EA, Joo IS, Huh K, Mook IH
- KMID: 2066182
- J Korean Neurol Assoc.
- 1999 Sep;17(5):688-693.
BACKGROUND: Ginseng extracts, known to enhance bodily functions including learning and memory, were reported to have in vitro neuroprotective activity in vitro. Here We demonstrate the possible therapeutic effects of... -
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- Ginsenoside Rg1 and 20(S)-Rg3 Induce IgA Production by Mouse B Cells
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Park HY, Lee SH, Lee KS, Yoon HK, Yoo YC, Lee J, Choi JE, Kim PH, Park SR
- KMID: 2132708
- Immune Netw.
- 2015 Dec;15(6):331-336.
- doi: 10.4110/in.2015.15.6.331
Ginsenosides are the major components of ginseng, which is known to modulate blood pressure, metabolism, and immune function, and has been used to treat various diseases. It has been reported... -
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- Ginsenosides Have a Suppressive Effect on c-Fos Expression in Brain and Reduce Cardiovascular Responses Increased by Noxious Stimulation to the Rat Tooth
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Jung JY, Seong KJ, Moon IO, Cho JH, Kim SH, Kim WJ
- KMID: 1429382
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):121-125.
- doi: 10.4196/kjpp.2013.17.2.121
The purpose of this study is to investigate the antinociceptive effects of ginsenosides on toothache. c-Fos immunoreactive (IR) neurons were examined after noxious intrapulpal stimulation (NS) by intrapulpal injection of... -
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- Bioconversion of Ginsenosides from Red Ginseng Extract Using Candida allociferrii JNO301 Isolated from Meju
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Lee S, Lee YH, Park JM, Bai DH, Jang JK, Park YS
- KMID: 2408968
- Mycobiology.
- 2014 Dec;42(4):368-375.
- doi: 10.5941/MYCO.2014.42.4.368
Red ginseng (Panax ginseng), a Korean traditional medicinal plant, contains a variety of ginsenosides as major functional components. It is necessary to remove sugar moieties from the major ginsenosides, which... -
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- Blood flow-improving activity of methyl jasmonate-treated adventitious roots of mountain ginseng
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Ban YH, Cha Y, Choi J, An ES, Lee JY, Han NR, Seo DW, Jung G, Jeong DH, Rhee MH, Choi EK, Kim YB
- KMID: 2407423
- Lab Anim Res.
- 2017 Jun;33(2):105-113.
- doi: 10.5625/lar.2017.33.2.105
Ginsenosides from Panax ginseng are well known for their diverse pharmacological effects including antithrombotic activity. Since adventitious roots of mountain ginseng (ARMG) also contain various ginsenosides, blood flow-improving effects of... -
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