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Immunoglobulin and T-cell receptor gene rearrangement analysis in malignant lymphoid neoplasms

Park CK, Kim CW, Kim IS, Lee JD

Gene rearrangement analysis using Southern-blot hybridization technique is a standard method for evaluating clonal receptor gene rearrangement. Both clonality and lineage can be identified in lymphoid neoplasms by the demonstration...
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Antigen receptor gene rearrangement patterns of lymphoproliferative diseases

Kim SH, Kim SY, Yoon HJ, Cho KS, Kim SI

  • KMID: 1697989
  • Korean J Intern Med.
  • 1991 Oct;41(4):524-541.
No abstract available.
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Gene rearrangement of specific exons of immunoglobulin heavy chain joining region in B- lymphoid leukemias

Park CJ, Cho HC, Uhmacher J

  • KMID: 1688373
  • Korean J Hematol.
  • 1993 Nov;28(2):307-312.
No abstract available.
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The Value of PCR Detection of TCR gamma Gene Rearrangement in the Diagnosis of Early Mycosis Fungoides

Choi TS, Ko JW, Jang MS, Suh KS, Kim ST

  • KMID: 2250972
  • Korean J Dermatol.
  • 2001 Nov;39(11):1231-1237.
BACKGROUND: The diagnosis and differential diagnosis of mycosis fungoides(MF) is often difficult, clinically and histologically. A variety of inflammatory dermatoses may be seen with similar clinical and histological features. Given...
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AML1/ETO Fusion Gene Expression and Clinical Characteristics of Adult Acute Myelogenous Leukemia

Lee SB, Kim YI, Yoon HJ, Kim SY, Cho KS

  • KMID: 1849136
  • Korean J Hematol.
  • 1998 Oct;33(3):311-321.
BACKGROUND: The (8;21) translocation is one of the most frequent karyotypic abnormalities detected in acute myelogenous leukemia (AML). Up to 92% of cases with this translocation are classified as FAB...
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detection of BCR-ABL gene rearrangement by use of the polymerase chain reaction in chronic myeloid leukemia

Kim JS, Kim JH, Uh WG, Kim SH, Kim SY, Yoon HJ, Cho KS

  • KMID: 1688309
  • Korean J Hematol.
  • 1993 May;28(1):71-80.
No abstract available.
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A Case of Nasal-type T/NK-cell Lymphoma Resembling Cellulitis

Park SJ, Kim SH, Lee ES

  • KMID: 2086479
  • Korean J Dermatol.
  • 2001 Aug;39(8):914-917.
T/NK-cell lymphoma shows biphenotype of the T-cell and NK-cell. This tumor is characterized by the absence of clonal rearrangement of T-cell receptor gene, frequent association with Epstein-Barr virus(EBV), poor clinical...
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Comparison of the Rate of Detection of Immunoglobulin Heavy Chain Gene Rearrangement by Fluoresecence In Situ Hybridization Probes in Multiple Myeloma

Chung HY, See CJ, Choi JE, Min HJ, Cho HI, Lee DS

BACKGROUND: Immunoglobulin heavy chain (IgH) gene rearrangement, which is frequently observed in multiple myeloma, can now be detected easily by using a fluorescence in situ hybridization (FISH) method. The aim...
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Cutaneous B-Cell Pseudolymphoma: Report of Two Cases

Chang SE, Kim KJ, Chang SE, Shin YH, Choi JH, Sung KJ, Moon KC, Koh JK

Cutaneous pseudolymphoma (CPL) has a microscopic appearance that resembles that of cutaneous lymphoma, but shows a clinically benign course. The differential diagnosis of CPL with cutaneous lymphoma is very important...
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A Case of T-cell Primary Pulmonary LymphomaDiagnosed by TCRgamma gene rearrangement

Choi YM, Kim SJ, Kwon SS, Kim YK, Kim KH, Moon HS, Park SH, Song JS

No abstract available.
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Two Cases of Philadelphia Chromosome-negative Essential Thrombocythemia Manifested bcr-abl Gene Rearrangement

Jung TK, Lee NY, Suh JS

  • KMID: 2146100
  • Korean J Clin Pathol.
  • 2001 Oct;21(5):327-330.
Discrepant results have been reported in terms of detecting bcr-abl transcripts in patients with essential thrombocythemia that are Philadelphia (Ph) chromosome-negative. We present two cases of Ph chromosome-negative essential thrombocythemia...
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Detection of IgH and Cyclin D1 gene Rearrangement with Interphase FISH in Multiple Myeloma

Huh JW, Ahn JY, Lee JH, Im SA, Seong CM, Chung WS

  • KMID: 2082779
  • Korean J Lab Med.
  • 2002 Oct;22(5):367-371.
BACKGROUND: The t(11;14)(q13;q32) is known to be one of the most frequent chromosomal abnor-malities found in multiple myeloma (MM). However, studies on t(11;14) in MM have been problemat-ic due to...
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A case of biphenotypic acute leukemia with expression of the AML1-ETO gene rearrangement

Seo JH, Lee HW, Lim JE, Chung JW, Choi JR, Yang WI, Min YH

  • KMID: 2257629
  • Korean J Med.
  • 2009 May;76(5):617-621.
Biphenotypic acute leukemia (BAL) is a subtype of acute leukemia that expresses two different immunophenotypic lineages, most commonly myeloid and either B- or T-lymphoid lineages. This entity has been defined...
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A Case of Acute Promyelocytic Leukemia with Phenotypic Change at Relapse

Kim H, Huh J, Seong C, Chung W

  • KMID: 2143204
  • Korean J Lab Med.
  • 2004 Dec;24(6):358-361.
Early diagnosis of acute promyelocytic leukemia (APL) depends primarily on morphological recognition before the presence of t(15;17) or PML-RAR gene rearrangement is confirmed. But the diagnosis is difficult to be...
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Molecular Diagnosis of Cutaneous T Cell Lymphoproliferative Diseases

Park JY, Lee MH, Kwak EK, Kim DJ, Park TI, Bae HI

  • KMID: 1725736
  • Korean J Pathol.
  • 2000 Nov;34(11):941-949.
It is often problematic to diagnose T-cell lymphoproliferative disorders of the skin because of the difficulty in establishing clonality in paraffin-embedded tissue. We used polymerase chain reaction single strand conformational...
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A Case of Myeloid Neoplasm with a PDGFRB Rearrangement and Eosinophilia

Cho NG, Kim D, Shim M, Chong SY

Myeloid neoplasia with eosinophilia and platelet-derived growth factor receptor beta (PDGFRB) rearrangements is an uncommon Philadelphia-negative myeloproliferative neoplasm. Their most common morphological diagnosis is chronic myelomonocytic leukemia with eosinophilia, which...
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CD20 Positive T Cell Lymphoma Involvement of Skin

Lee KY, Jeon SY, Hong JW, Kim YH, Song KH, Kim KH

  • KMID: 2383261
  • Ann Dermatol.
  • 2011 Nov;23(4):529-535.
CD20 positive T cell lymphoma is a rare condition that is associated with the coexpressions of CD20 and T cell markers, such as, CD3, CD5, or UCHL-1. Positivity for CD20...
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A Case of Therapy-related ALL with MLL Gene Rearrangement Following Treatment of Breast Cancer

Cho J, Hur M, Moon HW, Yun YM, Lee CH, Lee HG

ALL with MLL gene rearrangement secondary to chemotherapy has been rarely reported. We report a case of therapy-related ALL (t-ALL) with MLL gene rearrangement in a patient who had undergone...
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Analysis of Immunoglobulin Gene Rearrangement: Comparison between BIOMED-2 Multiplex PCR and Conventional Nested PCR

Sung JY, Kang SY, Kim SH, Kwon JE, Ko YH

BACKGROUND: Immunoglobulin (Ig) gene rearrangement analysis is a useful additional tool to detect clonality of B-lymphoproliferative disease and the method to detect immunoglobulin gene rearrangement is required the high sensitivity...
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Acute Monocytic Leukemia with t(11;17)(q23;q21) Involving a Rearrangement of Mixed Lineage Leukemia Gene

Kim KE, Kim SH, Han JY

A case of acute monocytic leukemia (AMoL) by French-American-British (FAB) classification in a 63-year-old male showed the abnormal karyotype 46,XY,t(11;17)(q23;q21), previously reported as a variant translocation in acute promyelocytic leukemia...
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