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Lipid Emulsions Enhance the Norepinephrine-Mediated Reversal of Local Anesthetic-Induced Vasodilation at Toxic Doses

Lee SH, Sung HJ, Ok SH, Yu J, Choi MJ, Lim JS, Sohn JT

PURPOSE: Intravenous lipid emulsions have been used to treat the systemic toxicity of local anesthetics. The goal of this in vitro study was to examine the effects of lipid emulsions...
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A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy

Shin HJ, Lim H

  • KMID: 2328241
  • J Korean Soc Clin Toxicol.
  • 2016 Jun;14(1):60-65.
Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine....
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Current Status of Intestinal Failure and Intestinal Transplantation

Ko JS

  • KMID: 2315332
  • Pediatr Gastroenterol Hepatol Nutr.
  • 2012 Sep;15(3):127-137.
Pediatric intestinal failure occurs secondary to short bowel syndrome, motility disorders, or malabsorption. The establishment of an intestinal rehabilitation program and the introduction of innovative surgical and medical treatments, such...
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Lipid Emulsion in the Successful Resuscitation of Local Anesthetic Toxicity after Ankle Block

Park SH, Kwak SH, Yoo KY, Lee HJ, Yook KB, Kim SJ

Unexpected occurrence of local anesthetic toxicity is not rare and can cause fatal complications that do not respond to any known drug of intervention. Recently, the successful use of lipid...
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Study on Hepatic Damage by Adriamycin- and Cisplatin-Lipiodol Emulsions Injected into Proper Hepatic Artery of Rabbits

Cho M, Moon TY, Lee SH, Sim MS, Kim CW, Kim S

  • KMID: 2143757
  • Korean J Gastroenterol.
  • 1998 Jan;31(1):73-81.
BACKGROUND AND AIMS: The present study was performed to evaluate chronic hepatic damage induced by adriamycin-lipiodol and cisplatin-lipiodol emulsions infused into the proper hepatic artery of rabbits. METHODS: Twenty- four...
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An Experimental Study on Mixing of Chemoembolic Material for Hepatocellular Carcinoma

Kim JH, Suh WH, Cha SJ, Suh JU, Cho WH, Kim WH, Hur G

  • KMID: 2345619
  • J Korean Radiol Soc.
  • 1994 Jun;30(6):1097-1103.
PURPOSE: The chemoembolization with Lipiodol and doxorubicin hydrochloride is used in patients with hepatocellular carcinoma. What condition is the ideal emulsion of Lipiodol and doxorubicin for excellent anticancer effect? METHOD AND MATERIALS: Microscopic...
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Lipofundin(R) MCT/LCT 20% increase left ventricular systolic pressure in an ex vivo rat heart model via increase of intracellular calcium level

Park J, Kim YA, Han JY, Jin S, Ok SH, Sohn JT, Lee HK, Chung YK, Shin IW

BACKGROUND: Lipid emulsions have been used to treat various drug toxicities and for total parenteral nutrition therapy. Their usefulness has also been confirmed in patients with local anesthetic-induced cardiac toxicity....
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Influence of Fish Oil-Containing Lipid Emulsions on Parenteral Nutrition-Associated Liver Disease in Neonates

Park JA, Park JE, Jeong MJ, Kim JS, Son ES, Eun HS

PURPOSE: This study is a comparative evaluation of the incidence of parenteral nutrition-associated liver disease (PNALD) when administering intravenous fat emulsions containing fish oil. METHODS: The medical records of patients who...
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Intravenous lipid emulsion therapy for cardiac arrest and refractory ventricular tachycardia due to multiple herb intoxication

Han S, Lim H, Noh H

Herbal products have been used for therapeutic purposes for a long time. However, many herbs can be toxic and even life-threatening. If refractory ventricular tachycardia (VT) is caused by herbal...
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Sudden Deaths of Neonates Receiving Intravenous Infusion of Lipid Emulsion Contaminated with Citrobacter freundii

Bae JY, Kang CK, Choi SJ, Lee E, Choe PG, Park WB, Kim NJ, Kim EC, Oh MD

At an intensive care unit, four neonates died consecutively within 80 minutes. Citrobacter freundii was isolated from blood samples of the 4 patients. It was also cultured from the leftover...
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Stability of Total Nutrient Admixtures

Kim DS, Hong YS, Kim SM

  • KMID: 2209259
  • J Korean Surg Soc.
  • 2000 Mar;58(3):307-318.
PURPOSE: Conventional intravenous nutrition has been given as a solution of amino acids combined with dextrose and a separate line delivering a lipid emulsion. This technique was unsatisfactory, however, because...
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Lipid emulsion-mediated reversal of toxic-dose aminoamide local anesthetic-induced vasodilation in isolated rat aorta

Ok SH, Han JY, Lee SH, Shin IW, Lee HK, Chung YK, Choi MJ, Sohn JT

BACKGROUND: Intravenous lipid emulsion has been used to treat systemic toxicity of local anesthetics. The goals of this in vitro study were to determine the ability of two lipid emulsions...
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Early Effective Parenteral Nutrition for Preterm Infants

Lee BS

  • KMID: 2144483
  • J Korean Soc Neonatol.
  • 2009 Nov;16(2):110-120.
Mimicking fetal nutrition is the goal of early paretneral nutrition (PN) in very low birth weight infants, however the limited metabolic capacity of immature organs raises concern about the toxicity...
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Effects of postoperative parenteral nutrition with different lipid emulsions in patients undergoing major abdominal surgery

Demirer S, Sapmaz A, Karaca AS, Kepenekci , Aydintug S, Balci D, Sonyurek P, Kose K

PURPOSE: This study was designed to investigate the effects of total parenteral nutrition (PN) using different lipid emulsions in patients undergoing major abdominal surgery. METHODS: Fifty-two patients were randomized to receive...
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Subconjunctival silicone oil drainage through the Molteno implant

Hyung SM, Min JP

To describe silicone oil drainage from the vitreous cavity to the subconjunctival space through a Molteno implant. A 52-year-old aphakic man with a Molteno implant inserted after lensectomy, vitrectomy and...
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Analysis of Adverse Reactions Associated with Parenteral Nutrition Use in Korea

Lee S, Ock M, Kim S, Kim H

PURPOSE: To evaluate the clinical manifestations of adverse drug reactions (ADRs) of parenteral nutrition (PN) use in Korea. METHODS: The Korean Adverse Event Reporting System (KAERS) database records in 2015 on...
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Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain

Byon HJ, Lee KW, Shim HY, Song JH, Jung JK, Cha YD, Lee DI

BACKGROUND: Lidocaine has been used widely to prevent propofol injection pain. Various methods of administration exist, such as lidocaine premixed with propofol or lidocaine pretreatment using a tourniquet, but it...
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A Current Research Insight into Function and Development of Adjuvants

Sohn ES, Son E, Pyo S

In recent years, adjuvants have received much attention because of the development of purified subunit and synthetic vaccines which are poor immunogens and require adjuvants to evoke the immune response....
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Intestinal Hypoganglionosis Leading to Intestinal Failure and the Compassionate Use of Omegavenâ„¢

Khalaf R, Karjoo S, Danielson , Wilsey M, Shakeel F

Intestinal hypoganglionosis is a rare innervation disorder that provides numerous nutritional, medical and surgical challenges. In this case report, we present a case of a newborn with intestinal hypoganglionosis leading...
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Temporary Opening of the Testis-blood Barrier by Triolein Fat Emulsion

Lee SD, Lee W, Kim HJ

PURPOSE: Although the purpose of the blood-testis barrier (BTB) is to protect germ cells from harmful influences, it also impedes the delivery of chemotherapeutic agents to the testis. This study...
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