- Reduced Expression of Cyclins and Proliferative Indices on the Psoriatic Epidermis after 12 Weeks of Oral Cyclosporin Therapy
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Han SS, Hyun OS, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK
- KMID: 1881992
- Ann Dermatol.
- 2006 Oct;18(2):51-58.
- doi: 10.5021/ad.2006.18.2.51
Cell growth characterized by cell cycle progression is regulated by cyclin-dependent kinase (CDK). CDKs are activated by binding cyclins such as cyclin A, cyclin B, cyclin D1, and cyclin E.... -
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- Expression of Cyclin B1 and cdc2 in Nodal Non-Hodgkin's Lymphoma and its Prognostic Implications
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Jin YH, Park CK
- KMID: 1101545
- J Korean Med Sci.
- 2002 Jun;17(3):322-327.
- doi: 10.3346/jkms.2002.17.3.322
To investigate the role of cyclin B1 and cdc2 in the pathogenesis and progression of malignant lymphoma, 68 cases of nodal non-Hodgkin's lymphoma were examined about the expression of cyclin... -
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- The Expression of Hypoxia Inducible Factor-1alpha and Its Correlation with the Expressions of Cyclin A1 and Cyclin B1 and the Clinicopathologic Factors of Uterine Cervical Carcinoma
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Pyo JY, Cho JH, Kim H, Park JP, Kim YT, Cho NH
- KMID: 1472549
- Korean J Pathol.
- 2009 Feb;43(1):13-19.
- doi: 10.4132/KoreanJPathol.2009.43.1.13
BACKGROUND: Hypoxia inducible factor-1alpha(HIF-1alpha) is a transcription factor for various target genes that are involved in adapting cells to hypoxia. It promotes cell proliferation and survival via modulation of such... -
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- Prognostic Implications of Cyclin B1, p34cdc2, p27(Kip1) and p53 Expression in Gastric Cancer
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Kim DH
- KMID: 2158177
- Yonsei Med J.
- 2007 Aug;48(4):694-700.
- doi: 10.3349/ymj.2007.48.4.694
PURPOSE: Cell cycle progression is regulated by interactions of specific cyclins and cyclin dependent kinases (CDKs) at the G1-S and G2-M checkpoints and cell cycle deregulation plays a major role... -
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- Cell cycle regulators during human atrial development
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Kim WH, Joo CU, Ku JH, Ryu CH, Koh KN, Koh GY, Ko JK
- KMID: 759076
- Korean J Intern Med.
- 1998 Jul;13(2):77-82.
OBJECTIVES: The molecular mechanisms that regulate cardiomyocyte cell cycle and terminal differentiation in humans remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs) and cyclin kinase inhibitors (CKIs)... -
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- Expression of Cell Cycle Related Genes in HL60 Cells Undergoing Apoptosis by X-irradiation
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Kim JH, Park IK
- KMID: 2323691
- J Korean Soc Ther Radiol Oncol.
- 1998 Dec;16(4):377-388.
PURPOSE: To evaluate changes in expression of cell cycle related genes during apoptosis induced in HL60 cells by X-irradiation to understand molecular biologic aspects in mechanism of radiation therapy. MATERIAL... -
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- Overexpression of Cell Cycle Proteins of Peripheral Lymphocytes in Patients with Alzheimer's Disease
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Kim H, Kwon YA, Ahn IS, Kim S, Kim S, Jo SA, Kim DK
- KMID: 2316605
- Psychiatry Investig.
- 2016 Jan;13(1):127-134.
- doi: 10.4306/pi.2016.13.1.127
OBJECTIVE: Biological markers for Alzheimer's disease (AD) will help clinicians make objective diagnoses early during the course of dementia. Previous studies have suggested that cell cycle dysregulation begins earlier than... -
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- Overexpressions of Cyclin B1, cdc2, p16 and p53 in Human Breast Cancer: The Clinicopathologic Correlations and Prognostic Implications
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Chae SW, Sohn JH, Kim DH, Choi YJ, Park YL, Kim K, Cho YH, Pyo JS, Kim JH
- KMID: 1777016
- Yonsei Med J.
- 2011 May;52(3):445-453.
- doi: 10.3349/ymj.2011.52.3.445
PURPOSE: The molecular mechanisms that are responsible for the initiation and progression of breast cancers are largely unknown. This study was to analyze the cyclin B1, cdc2, p53 and p16... -
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- Expression of Cyclin Genes in Cervical Carcinomas
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Cho JH, Cha SD, Lee TS, Cho CH, Baek WK, Suh SI, Suh MH
- KMID: 1925220
- Korean J Obstet Gynecol.
- 1997 Nov;40(11):2457-2463.
Human papillomavirus(HPV) infection is one of the common sexual transmitted infections in Korea, and evidence that HPV plays a central role in the development of cervical cancer and its precusors... -
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- Correlation between Gene Expression of MDR1, Cyclin B, MAD2 and BAX in Childhood Acute Lymphocytic Leukemia
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Kim WD, Kwon TK, Choi KH, Hah JO
- KMID: 1979924
- Korean J Pediatr Hematol Oncol.
- 2000 Apr;7(1):57-63.
PURPOSE: Although outcome of the children with ALL has been improved remarkably with the multidrug chemotherapy and supportive therapy, relapse is still important cause of treatment failure. One of... -
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- RNA-sequencing Profiles of Cell Cycle–Related Genes Upregulated during the G2-Phase in Giardia lamblia
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Kim J, Shin MY, Park SJ
- KMID: 2448151
- Korean J Parasitol.
- 2019 Apr;57(2):185-189.
- doi: 10.3347/kjp.2019.57.2.185
To identify the component(s) involved in cell cycle control in the protozoan Giardia lamblia, cells arrested at the G1/S- or G2-phase by treatment with nocodazole and aphidicolin were prepared from... -
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- Identification of Molecular Signatures in Mild Intrinsic Atopic Dermatitis by Bioinformatics Analysis
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Yin H, Wang S, Gu C
- KMID: 2471339
- Ann Dermatol.
- 2020 Apr;32(2):130-140.
- doi: 10.5021/ad.2020.32.2.130
BACKGROUND: Atopic dermatitis (AD) is recognized as a common inflammatory skin disease and frequently occurred in Asian and Black individuals. OBJECTIVE: Since the limitation of dataset associated with human severe AD,... -
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- Development of a Novel Nonradioisotopic Assay and Cdc25B Overexpression Cell Lines for Use in Screening for Cdc25B Inhibitors
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Ha GS, Lee CM, Kim CW
- KMID: 2419735
- Yonsei Med J.
- 2018 Oct;59(8):995-1003.
- doi: 10.3349/ymj.2018.59.8.995
PURPOSE: The cyclin-dependent kinase 1 (Cdk1) and cyclin B complex performs important roles in the transition from the G2 to M phase in the cell cycle through removal of inhibitory... -
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- p53 Prevents Immature Escaping from Cell Cycle G2 Checkpoint Arrest through Inhibiting cdk2-dependent NF-Y Phosphorylation
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Yun UJ, Park HD, Shin DY
- KMID: 2166051
- Cancer Res Treat.
- 2006 Dec;38(4):224-228.
PURPOSE: Recent studies have suggested that p53 regulates the G2 checkpoint in the cell cycle and this function is required for the maintenance of genomic integrity. In this study, we... -
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- The Correlation between the Expression of CD99 and the Cell Cycle
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Yu CS, Chang MC, Oh SK
- KMID: 2145187
- J Korean Surg Soc.
- 2001 Oct;61(4):347-356.
PURPOSE: The cell cycle control system is necessary for the normal growth and differentiation of cells. The purposes of this study were to compare CD99 expression with a known... -
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- Sorbus rufopilosa Extract Exhibits Antioxidant and Anticancer Activities by Inducing Cell Cycle Arrest and Apoptosis in Human Colon Adenocarcinoma HT29 Cells
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Oh YN, Jin S, Park HJ, Kwon HJ, Kim BW
- KMID: 2367562
- J Cancer Prev.
- 2016 Dec;21(4):249-256.
- doi: 10.15430/JCP.2016.21.4.249
BACKGROUND: Sorbus rufopilosa, a tsema rowan, is a species of the small ornamental trees in the genus Sorbus and the family Rosaceae found in East Asia. The bioactivities of S.... -
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- Preferential Cytotoxic Effect of Genistein on G361 Melanoma Cells Via Inhibition of the Expression of Focal Adhesion Kinase
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Park SR, Kwak HH, Park BS, Kim GC
- KMID: 1431133
- Int J Oral Biol.
- 2012 Dec;37(4):189-195.
Resistance to the induction of apoptosis is a possible mechanism by which tumor cells can survive anti-neoplastic treatments. Melanoma is notoriously resistant to anti-neoplastic therapy. Previous studies have demonstrated focal... -
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- Relationship between Expression of Anaphase-promoting Complex and Prognostic Factors in Invasive Ductal Carcinoma of Breast
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Eom M, Park KH, Lee KG, Yi SY, Kang Y, Jung SH
- KMID: 1725952
- Korean J Pathol.
- 2003 Feb;37(1):19-25.
BACKGROUND: The role of the anaphase-promoting complex (APC) is to promote the degradation of mitotic cyclins and other substrates involved in sister chromatid adhesions. The APC appears to be responsible... -
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- Pseudomonas aeruginosa Exotoxin A Reduces Chemoresistance of Oral Squamous Carcinoma Cell via Inhibition of Heat Shock Proteins 70 (HSP70)
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Park SR, Lee KD, Kim UK, Gil YG, Oh KS, Park BS, Kim GC
- KMID: 1071422
- Yonsei Med J.
- 2010 Sep;51(5):708-716.
- doi: 10.3349/ymj.2010.51.5.708
PURPOSE: Oral squamous carcinoma (OSCC) cells exhibit resistance to chemotherapeutic agent-mediated apoptosis in the late stage of malignancy. Increased levels of heat shock proteins 70 (HSP70) in cancer cells are... -
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- Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells
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Hong YB, Kang HJ, Kim HJ, Rosen EM, Dakshanamurthy S, Rondanin R, Baruchello R, Grisolia G, Daniele S, Bae I
- KMID: 1123462
- Exp Mol Med.
- 2009 Mar;41(3):151-160.
- doi: 10.3858/emm.2009.41.3.018
Resveratrol has been reported to possess cancer preventive properties. In this study, we analyzed anti-tumor activity of a newly synthesized resveratrol analog, cis-3,4',5-trimethoxy-3'-hydroxystilbene (hereafter called 11b) towards breast and pancreatic... -
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