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Spreading Shape and Area Regulate the Osteogenesis of Mesenchymal Stem Cells

Zhao Y, Sun Q, Wang S, Huo B

BACKGROUND: Mesenchymal stem cells (MSCs) have strong self-renewal ability and multiple differentiation potential. Some studies confirmed that spreading shape and area of single MSCs influence cell differentiation, but few studies...
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Morphometric Analysis of the Rabbit Corneal Endothelium Specular Microscopy Versus Alizarin Red S Staining

Baik JM, Kim KS

  • KMID: 2127615
  • J Korean Ophthalmol Soc.
  • 1991 Aug;32(8):629-632.
Analysis of endothelial morphology by computer assisted digitizer and image analysis program provides very useful indices of cell shape and size which appear to correlate to the monolayer's functional status....
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Morphological Changes of Cultured Rat Hepatocytes Induced by Phalloidin and Cytochalasin D

Park KH, Kim JB, Ahn ET, Ko JS, Kim JG

  • KMID: 2224528
  • Korean J Anat.
  • 2000 Dec;33(6):665-676.
The microfilaments of hepatocyte are distributed throughout the vicinity of cell membranes, especially numerous around the region of bile canaliculus, and provide the maintenance of cell shape, cellular wall tension,...
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Ezrin is an Essential Marker for Metastasis of Gynecologic Cancer

Choi SD

  • KMID: 2365471
  • J Korean Soc Menopause.
  • 2012 Aug;18(2):81-93.
Ezrin, a membrane cytoskeleton linking protein, is a member of ezrin/radixin/moesin (ERM) that regulates cell shape, motility and cell to cell interaction via linking the contractile elements of the cell...
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Effects of Polylysine Coating on GH3 Rat Pituitary Tumor Cells in Culture

Kim JJ, Baik SH, Hwang DH, Hwang YI, Lee WJ, Lee BL

  • KMID: 1530108
  • Korean J Anat.
  • 1998 Jun;31(3):429-437.
GH3 cells are derived from rat pituitary tumor cells that secrete prolactin and growth hormone, and important in studying prolactin-secreting pitutary tumors. This study was performed to examine the effects...
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Effects of Taxol and Mitomycin C on Morphologic Alteration of Cultured Rabbit Subconjunctival Fibroblasts

Baek YW, Moon JI, Park CK

  • KMID: 2206429
  • J Korean Ophthalmol Soc.
  • 2003 Jan;44(1):202-207.
PURPOSE: Scar tissue formation by cell proliferation, migration and contraction of fibroblasts may result in the failure of trabeculectomy. The author investigated effects of Mitomycin C (MMC) and Taxol on...
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Ultrastructural Changes of the Cultured Hepatocytes in Microfilamentous Dysfunction induced by Drugs

Kim JG, Ko JS, Ahn ET, Park KH

  • KMID: 2092700
  • Korean J Anat.
  • 1999 Oct;32(5):661-671.
To examine the role of actin microfilaments which are located at beneath the plasma membrane, we observed the ultrastructural changes of rat hepatocyte induced by alteration of the microfilamentous integrity....
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Meniscus Reconstruction in Partially Removed Meniscus with Reflected Synovio-capsular Flap in Rabbit

Kim JM, Kim JY, Sung JH, Kim WY, Han CW, Ryu JD, Joung YH

  • KMID: 2189537
  • J Korean Orthop Assoc.
  • 1999 Feb;34(1):73-81.
PURPOSE: The purpose of this paper was to investigate whether the reflected synovio-capsular flap, covering one-third of the remaining peripheral after partial removal of two-thirds of the central medial meniscus...
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Acetaminophen Induced Cytotoxicity and Altered Gene Expression in Cultured Cardiomyocytes of H9C2 Cells

Jin SM, Park K

  • KMID: 2380178
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012011.
OBJECTIVES: Hepatotoxicity of acetaminophen has been widely studied. However, the adverse effects on the heart have not been sufficiently evaluated. This study was performed to investigate cytotoxicity and alterations of...
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Effects of Age and Gender on the Viability and Stem Cell Markers, mRNA, and Protein Expression of Bone Marrow-Derived Stem Cells Cultured in Growth Media

Lee H, Lee H, Na CB, Park JB

PURPOSE: Bone marrow has long been a source of primary cells. This study was performed to evaluate the effects of age and sex on the cellular viability and expression of...
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Effects of Uniaxial Cyclic Stretch Loading on Morphology of Adipose Derived Stem Cells

Rabbani M, Janmaleki , Tafazzoli-Shadpour M, Teymoori M, Rezvaninejad S

Adipose derived stem cells (ADSC) are good candidates for the replacement of bone marrow derived mesenchymal stem cells due to their abundance, multipotency property, and easier accessibility. In order to...
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Changes of Corneal Endothelium and Surrounding Tissues After Implantation of IOLAB-IOL and UNI-IOL in Rabbit's eyes

Ahn MD, Kim JH

  • KMID: 2107484
  • J Korean Ophthalmol Soc.
  • 1987 Dec;28(6):1205-1217.
The aim of this study was to evaluate the degree of tolerance of the rabbit's eye when UNI-IOL, prototype of posterior intraocular lens, manufactured in Korea was implanted into the...
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The Effect of Anterior Chamber Irrigation with OcuLarsol(R) on the Corneal Endothelial Cells

Lee JT, Song JS, Kim HM, Kim KS

  • KMID: 2337084
  • J Korean Ophthalmol Soc.
  • 2003 Feb;44(2):429-436.
PURPOSE: To verify the stability and effect of OcuLarsol(R), which was newly developed for irrigating solution, by evaluating influence on cornea. METHODS: In vivo study group, after an irrigation and...
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Current review of molecular biology in distraction osteogenesis

Jee YJ, Song HC, Kim YG, Kim J, Kim CH

  • KMID: 1961151
  • J Korean Assoc Oral Maxillofac Surg.
  • 2002 Dec;28(6):456-463.
Distraction osteogenesis is a well-established clinical treatment for limb length discrepancy and skeletal deformities. Appropriate mechanical tension-stress is believed not to break the callus but rather to stimulate osteogenesis. In...
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A study on the responses of osteoblasts to various surface-treated titanium

Lee JM, Kim YS, Kim CW, Jang KS, Lim YJ

  • KMID: 2196147
  • J Korean Acad Prosthodont.
  • 2004 Jun;42(3):307-326.
STATEMENT OF PROBLEM: The long-term success of implants is the development of a stable direct connection between bone and implant surface, which must be structural and functional. To improve a...
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Forskolin promotes astroglial differentiation of human central neurocytoma cells

Kim BJ, Kim SS, Kim YI, Paek SH, Lee YD, Suh-Kim H

  • KMID: 755665
  • Exp Mol Med.
  • 2004 Feb;36(1):52-56.
Human central neurocytoma is a kind of the brain tumors that are usually found in anterior part of the lateral ventricles. In this study, we established conditions that allowed proliferation...
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Norcantharidin Induces Human Melanoma A375-S2 Cell Apoptosis through Mitochondrial and Caspase Pathways

An WW, Wang MW, Tashiro SI, Onodera S, Ikejima T

Norcantharidin (NCTD) is the demethylated form of cantharidin, which is the active substance of mylabris. To examine the pathway of NCTD-induced A375-S2 cell death, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-dipheyltetrazolium bromide (MTT) assay,...
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Transfection of Insulin-like Growth Factor II Gene into Human Anterior Cruciate Ligament-derived Fibroblasts

Song EK, Shim SD, Kim MS, Choi J

  • KMID: 2274959
  • Chonnam Med J.
  • 2002 Dec;38(4):396-402.
Gene therapy using growth factors in the treatment of tissue injuries plays a very important role in improving the wound healing process and regeneration of such as bones, cartilages and...
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Bis induces growth inhibition and differentiation of HL-60 cells via up-regulation of p27

Seo YJ, Jeon MH, Lee JH, Lee YJ, Youn HJ, Ko JH, Lee JH

  • KMID: 1116208
  • Exp Mol Med.
  • 2005 Dec;37(6):624-630.
Bis (Bag-3, CAIR), a Bcl-2-interacting protein, promotes the anti-apoptotic activity of Bcl-2 and increased levels of Bis have been observed in several disease models. The involvement of Bcl-2 and some...
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Neuronal loss in primary long-term cortical culture involves neurodegeneration-like cell death via calpain and p35 processing, but not developmental apoptosis or aging

Kim MJ, Oh SJ, Park SH, Kang HJ, Won MH, Kang TC, Park JB, Kim JI, Kim J, Lee JY

  • KMID: 1103677
  • Exp Mol Med.
  • 2007 Feb;39(1):14-26.
Primary neuronal culture is a powerful tool to study neuronal development, aging, and degeneration. However, cultured neurons show signs of cell death after 2 or 3 weeks. Although the mechanism...
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