- Cell proliferation index and the expression of p53 and Bcl-2 in tumorous and non-tumorous lesions of hepatocellular carcinoma and metastatic liver cancer
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Yoon DS, Cheong JH, Park YN, Kwon SW, Chi HS, Kim BR
- KMID: 711579
- Yonsei Med J.
- 1998 Oct;39(5):424-429.
- doi: 10.3349/ymj.1998.39.5.424
In the development of a cancer, unlimited cell proliferation has been believed to play an important role. In addition, a programmed cell death called apoptosis, which is regulated by several... -
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- Exophytic combined hepatocellular carcinoma and cholangiocarcinoma
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Noh SJ, Lee HK, Yu HC, Moon WS
- KMID: 1410900
- Clin Mol Hepatol.
- 2012 Dec;18(4):416-419.
- doi: 10.3350/cmh.2012.18.4.416
No abstract available. -
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- Clinicopathological Significance of Expression of Tspan-1, Jab1 and p27 in Human Hepatocellular Carcinoma
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Chen L, Yuan D, Wang GL, Wang Y, Wu YY, Zhu J
- KMID: 2157846
- J Korean Med Sci.
- 2010 Oct;25(10):1438-1442.
- doi: 10.3346/jkms.2010.25.10.1438
The aim of this study was to investigate the expression of Tspan-1, Jab1 and p27 in human hepatocellular carcinoma (HCC) and their clinicopathological significance. The expression of Tspan-1, Jab1 and... -
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- Expression of beta-catenin in Hepatocellular Carcinoma in Relation to Tumor Cell Proliferation and Cyclin D1 Expression
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Joo M, Lee HK, Kang YK
- KMID: 2157624
- J Korean Med Sci.
- 2003 Apr;18(2):211-217.
- doi: 10.3346/jkms.2003.18.2.211
Alteration of beta-catenin expression has been implicated in the development of hepatocellular carcinoma (HCC). It has been also reported that beta-catenin can influence the tumor cell proliferation or cyclin D1... -
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- Clinicopathologic significance of the expression of Snail in hepatocellular carcinoma
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Woo HY, Min AL, Choi JY, Bae SH, Yoon SK, Jung CK
- KMID: 1105509
- Korean J Hepatol.
- 2011 Mar;17(1):12-18.
- doi: 10.3350/kjhep.2011.17.1.12
BACKGROUND/AIMS: E-cadherin is involved in intercellular binding and cellular polarity formation. Snail is a key regulator of the epithelial-mesenchymal transition and is closely associated with tumor invasiveness due to its... -
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- Different protein-binding patterns in the P3 promoter region of the human insulin-like growth factor II gene in the human liver cirrhosis and hepatocellular carcinoma tissues
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Seo JH, Kim KW, Park BC
- KMID: 1064965
- J Korean Med Sci.
- 1998 Apr;13(2):171-178.
- doi: 10.3346/jkms.1998.13.2.171
The P3 promoter of the human insulin-like growth factor II (IGF-II) is the major IGF-II promoter in fetal liver (FL) and hepatocellular carcinoma (HCC). However, little information is available... -
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- Hepatic Angiomyolipoma with Variable Histologic Features: 8 Cases Resembling Hepatocellular Carcinoma or Inflammatory Pseudotumor
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Hwang I, Yu E, Cho KJ
- KMID: 1775808
- Korean J Gastroenterol.
- 2012 Oct;60(4):242-248.
- doi: 10.4166/kjg.2012.60.4.242
BACKGROUND/AIMS: Hepatic angiomyolipoma (AML) is a rare mesenchymal tumor of the liver and demonstrates a marked histologic diversity. HMB-45 is a promising immunomarker for this tumor and especially helpful to... -
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- Expression of Transforming Growth Factor beta-1 in Chronic Hepatitis and Hepatocellular Carcinoma Associated with Hepatitis C Virus Infection
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Kim HG, Chung YH, Song BC, Kim JA, Yang SH, Lee YS, Suh DJ
- KMID: 759514
- Korean J Intern Med.
- 2000 Dec;15(3):165-170.
BACKGROUND: Transforming growth factor beta-1 (TGF beta 1) has been suggested to play a role in the development, growth or progression of hepatocellular carcinoma (HCC). Genotype and serum titer of... -
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- Lack of colocalization of HBxAg and insulin like growth factor II in the livers of patients with chronic hepatitis B, cirrhosis and hepatocellular carcinoma
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Seo JH, Kim KW, Murakami S, Park BC
- KMID: 645113
- J Korean Med Sci.
- 1997 Dec;12(6):523-531.
- doi: 10.3346/jkms.1997.12.6.523
To evaluate the possibility that HBxAg is related to an enhanced expression of IGF-II, immunohistochemical staining was performed for distribution and colocalization of HBxAg and IGF-II in liver tissues... -
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- Complete Tumor Resection for a Hepatocellular Carcinoma Secreting Parathyroid Hormone-related Peptide
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Kim EK, Kim JS, Shin KC, Lee GT, Han CJ, Kim SB, Ku YH
- KMID: 2373325
- Korean J Gastroenterol.
- 2015 Aug;66(2):122-126.
- doi: 10.4166/kjg.2015.66.2.122
Hepatocellular carcinoma (HCC) is the fifth most common cancer in Korea. Diverse paraneoplastic syndromes can occur in patients with HCC, but parathyroid hormone-related peptide (PTH-rP)-induced hypercalcemia is uncommon. Hypercalcemia due... -
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- Expression of Tissue Inhibitors of Metalloproteinases (TIMPs) in Hepatocellular Carcinoma
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Joo YE, Seo YH, Lee WS, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ
- KMID: 759515
- Korean J Intern Med.
- 2000 Dec;15(3):171-178.
BACKGROUND: Matrix metalloproteinases (MMPs) have been implicated in the remodelling of extracellular matrix (ECM), including basement membrane. ECM remodelling is associated with pathological processes, including hepatic fibrosis, tumor invasion and... -
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- Influence of P53 on the radiotherapy response of hepatocellular carcinoma
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Gomes AR, Abrantes A, Brito AF, Laranjo M, Casalta-Lopes JE, Goncalves , Sarmento-Ribeiro AB, Botelho MF, Tralhao JG
- KMID: 2351026
- Clin Mol Hepatol.
- 2015 Sep;21(3):257-267.
- doi: 10.3350/cmh.2015.21.3.257
BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms... -
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- Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells
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Gu HR, Park SC, Choi SJ, Lee JC, Kim YC, Han CJ, Kim J, Yang KY, Kim YJ, Noh GY, No SH, Jeong JH
- KMID: 2155291
- Clin Mol Hepatol.
- 2015 Mar;21(1):49-59.
- doi: 10.3350/cmh.2015.21.1.49
BACKGROUND/AIMS: Silibinin, the main component of silymarin, is used as a hepatoprotectant and exhibits anticancer effects against various cancer cells. This study evaluated the effects of a combination of silibinin... -
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- OTX1 Contributes to Hepatocellular Carcinoma Progression by Regulation of ERK/MAPK Pathway
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Li H, Miao Q, Xu CW, Huang JH, Zhou YF, Wu MJ
- KMID: 2373748
- J Korean Med Sci.
- 2016 Aug;31(8):1215-1223.
- doi: 10.3346/jkms.2016.31.8.1215
Orthodenticlehomeobox 1 (OTX1) overexpression had previously been associated with the progression of several tumors. The present study aimed to determine the expression and role of OTX1 in human hepatocellular carcinoma... -
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- Preoperative Radiologic and Postoperative Pathologic Risk Factors for Early Intra-Hepatic Recurrence in Hepatocellular Carcinoma Patients Who Underwent Curative Resection
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Kim H, Park MS, Park YN, Kim H, Kim KS, Choi JS, Ahn SH, Han KH, Kim MJ, Kim KW
- KMID: 1777092
- Yonsei Med J.
- 2009 Dec;50(6):789-795.
- doi: 10.3349/ymj.2009.50.6.789
PURPOSE: The risk of hepatocellular carcinoma (HCC) recurrence must be considered ahead of surgery. This study was undertaken to identify pre-operative risk factors for early intrahepatic recurrence of HCC after... -
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- Fibroblast growth factor receptor isotype expression and its association with overall survival in patients with hepatocellular carcinoma
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Lee HJ, Kang HJ, Kim KM, Yu ES, Kim KH, Kim SM, Kim TW, Shim JH, Lim YS, Lee HC, Chung YH, Lee YS
- KMID: 2155292
- Clin Mol Hepatol.
- 2015 Mar;21(1):60-70.
- doi: 10.3350/cmh.2015.21.1.60
BACKGROUND/AIMS: Fibroblast growth factor signaling is involved in hepatocarcinogenesis. The aim of this study was to determine the fibroblast growth factor receptor (FGFR) isotype expression in hepatocellular carcinoma (HCC) and... -
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- Prognostic value of serum osteopontin in hepatocellular carcinoma patients treated with transarterial chemoembolization
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Kim SH, Chung YH, Yang SH, Kim JA, Jang MK, Kim SE, Lee D, Lee SH, Lee D, Kim KM, Lim YS, Lee HC, Lee YS, Suh DJ
- KMID: 1374960
- Korean J Hepatol.
- 2009 Sep;15(3):320-330.
- doi: 10.3350/kjhep.2009.15.3.320
BACKGROUND/AIMS: Osteopontin (OPN) is overexpressed in hepatocellular carcinoma (HCC) with postoperative recurrence or extrahepatic metastasis. However, its prognostic value in patients treated with transarterial chemoembolization (TACE) is unclear. We investigated... -
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- Impact of serum C-reactive protein level on the prognosis of patients with hepatocellular carcinoma undergoing TACE
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Jun CH, Ki HS, Lee KH, Park KJ, Park SY, Cho SB, Park CH, Joo YE, Kim HS, Choi SK, Rew JS
- KMID: 1493577
- Clin Mol Hepatol.
- 2013 Mar;19(1):70-77.
- doi: 10.3350/cmh.2013.19.1.70
BACKGROUND/AIMS: The aim of this study was to determine the relationship between serum CRP levels and the prognosis of hepatocellular carcinoma (HCC) patients. METHODS: HCC patients who underwent the first session... -
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- Apparent Diffusion Coefficient Value of Diffusion-Weighted Imaging for Hepatocellular Carcinoma: Correlation with the Histologic Differentiation and the Expression of Vascular Endothelial Growth Factor
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Heo SH, Jeong YY, Shin SS, Kim JW, Lim HS, Lee JH, Koh YS, Cho CK, Kang HK
- KMID: 946269
- Korean J Radiol.
- 2010 Jun;11(3):295-303.
- doi: 10.3348/kjr.2010.11.3.295
OBJECTIVE: To evaluate whether the histopathological differentiation and the expression of vascular endothelial growth factor (VEGF) of hepatocellular carcinoma (HCC) do show correlation with the apparent diffusion coefficient (ADC) value... -
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- Effects of Benzo(a)pyrene on the Expression of Heat Shock Proteins, Pro-inflammatory Cytokines and Antioxidant Enzymes in Hepatic Tumors Induced by Rat Hepatoma N1-S1 Cells
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Zheng Z, Park SY, Lee M, Phark S, Won NH, Kang HS, Sul D
- KMID: 1782110
- J Korean Med Sci.
- 2011 Feb;26(2):222-230.
- doi: 10.3346/jkms.2011.26.2.222
Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is easily introduced to humans via consumption of grilled or smoked meat. BaP causes harmful oxidative effects on cell development, growth... -
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