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Severe Hepatic Sinusoidal Obstruction Syndrome in a Child Receiving Vincristine, Actinomycin-D, and Cyclophosphamide for Rhabdomyosarcoma: Successful Treatment with Defibrotide

Choi A, Kang YK, Lim S, Kim DH, Lim JS, Lee JA

  • Cancer Res Treat.
  • 2016 Oct;48(4):1443-1447.
  • doi: 10.4143/crt.2016.096
Hepatic sinusoidal obstruction syndrome (SOS) is a life-threatening syndrome that generally occurs as a complication after hematopoietic stem cell transplantation or, less commonly, after conventional chemotherapy. Regarding SOS in rhabdomyosarcoma...
Coexistence of VHL Disease and CPT2 Deficiency: A Case Report

Ferrara AM, Sciacco M, Zovato S, Rizzati S, Colombo I, Boaretto F, Moggio M, Opocher G

  • Cancer Res Treat.
  • 2016 Oct;48(4):1438-1442.
  • doi: 10.4143/crt.2015.450
von Hippel-Lindau (VHL) disease is an inherited syndrome manifesting with benign and malignant tumors. Deficiency of carnitine palmitoyltransferase type II (CPT2) is a disorder of lipid metabolism that, in the...
A Pilot Study Evaluating Steroid-Induced Diabetes after Antiemetic Dexamethasone Therapy in Chemotherapy-Treated Cancer Patients

Jeong Y, Han HS, Lee HD, Yang J, Jeong J, Choi MK, Kwon J, Jeon HJ, Oh TK, Lee KH, Kim ST

  • Cancer Res Treat.
  • 2016 Oct;48(4):1429-1437.
  • doi: 10.4143/crt.2015.464
PURPOSE: Dexamethasone is a mainstay antiemetic regimen for the prevention of chemotherapy-induced nausea and vomiting. The aim of this pilot study was to assess the incidence of and factors associated...
Clinical Practices and Outcomes on Chemotherapy-Induced Nausea and Vomiting Management in South Korea: Comparison with Asia-Pacific Data of the Pan Australasian Chemotherapy Induced Emesis Burden of Illness Study

Lee MA, Cho EK, Oh SY, Ahn JB, Lee JY, Burke T, Jung H, Kim JG

  • Cancer Res Treat.
  • 2016 Oct;48(4):1420-1428.
  • doi: 10.4143/crt.2015.309
PURPOSE: This study reported patient outcomes of chemotherapy-induced nausea and vomiting (CINV) prophylaxis for highly emetogenic chemotherapy (HEC) and moderately emetogenic chemotherapy (MEC) regimens and evaluated its adherence to acute-phase...
Tandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation for Atypical Teratoid/Rhabdoid Tumor

Sung KW, Lim DH, Yi ES, Choi YB, Lee JW, Yoo KH, Koo HH, Kim JH, Suh YL, Joung YS, Shin HJ

  • Cancer Res Treat.
  • 2016 Oct;48(4):1408-1419.
  • doi: 10.4143/crt.2015.347
PURPOSE: We prospectively evaluated the effectiveness of tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT) in improving the survival of patients with atypical teratoid/rhabdoid tumors while reducing the risks...
Clinical Significance of Tyrosine Hydroxylase mRNA Transcripts in Peripheral Blood at Diagnosis in Patients with Neuroblastoma

Lee NH, Son MH, Choi YB, Yi E, Lee JW, Yoo KH, Sung KW, Koo HH

  • Cancer Res Treat.
  • 2016 Oct;48(4):1399-1407.
  • doi: 10.4143/crt.2015.481
PURPOSE: The purpose of this study is to investigate the clinical significance of tyrosine hydroxylase (TH) expression in peripheral blood (PB) at diagnosis in patients with neuroblastoma. MATERIALS AND METHODS: TH...
Clinical Features of Male Breast Cancer: Experiences from Seven Institutions Over 20 Years

Hong JH, Ha KS, Jung YH, Won HS, An HJ, Lee GJ, Kang D, Park JC, Park S, Byun JH, Suh YJ, Kim JS, Park WC, Jung SS, Park IY, Chung SM, Woo IS

  • Cancer Res Treat.
  • 2016 Oct;48(4):1389-1398.
  • doi: 10.4143/crt.2015.410
PURPOSE: Breast cancer treatment has progressed significantly over the past 20 years. However, knowledge regarding male breast cancer (MBC) is sparse because of its rarity. This study is an investigation...
Clinicopathologic Features and Long-Term Outcomes of Elderly Breast Cancer Patients: Experiences at a Single Institution in Korea

Kim HK, Ham JS, Byeon S, Yoo KH, Jung KS, Song HN, Cho J, Lee JY, Lim SH, Kim HS, Kim JY, Lee JE, Kim SW, Nam SJ, Lee SK, Bae SY, Ahn JS, Im YH, Park YH

  • Cancer Res Treat.
  • 2016 Oct;48(4):1382-1388.
  • doi: 10.4143/crt.2015.423
PURPOSE: The purpose of this study was to assess the tumor characteristics and long-term clinical outcomes of adjuvant treatments after surgery with a curative aim for patients with breast cancer...
Prognostic Value of Axillary Nodal Ratio after Neoadjuvant Chemotherapy of Doxorubicin/Cyclophosphamide Followed by Docetaxel in Breast Cancer: A Multicenter Retrospective Cohort Study

Kim SH, Jung KH, Kim TY, Im SA, Choi IS, Chae YS, Baek SK, Kang SY, Park S, Park IH, Lee KS, Choi YJ, Lee S, Sohn JH, Park YH, Im YH, Ahn JH, Kim SB, Kim JH

  • Cancer Res Treat.
  • 2016 Oct;48(4):1373-1381.
  • doi: 10.4143/crt.2015.475
PURPOSE: The purpose of this study is to investigate the prognostic value of lymph node (LN) ratio (LNR) in patients with breast cancer after neoadjuvant chemotherapy. MATERIALS AND METHODS: This retrospective...
Locoregional Recurrence by Tumor Biology in Breast Cancer Patients after Preoperative Chemotherapy and Breast Conservation Treatment

Jwa E, Shin KH, Kim JY, Park YH, Jung SY, Lee ES, Park IH, Lee KS, Ro J, Kim YJ, Kim TH

  • Cancer Res Treat.
  • 2016 Oct;48(4):1363-1372.
  • doi: 10.4143/crt.2015.456
PURPOSE: The purpose of this study is to determine whether breast cancer subtype can affect locoregional recurrence (LRR) and ipsilateral breast tumor recurrence (IBTR) after neoadjuvant chemotherapy (NAC) and breast-conserving...
Survival Outcome of Combined GnRH Agonist and Tamoxifen Is Comparable to That of Sequential Adriamycin and Cyclophosphamide Chemotherapy Plus Tamoxifen in Premenopausal Patients with Lymph-Node–Negative, Hormone-Responsive, HER2-Negative, T1-T2 Breast C

Sohn G, Ahn SH, Kim HJ, Son BH, Lee JW, Ko BS, Lee Y, Lee SB, Baek S

  • Cancer Res Treat.
  • 2016 Oct;48(4):1351-1362.
  • doi: 10.4143/crt.2015.444
PURPOSE: The purpose of this study was to compare treatment outcomes between combined gonadotropin-releasing hormone agonist and tamoxifen (GnRHa+T) and sequential adriamycin and cyclophosphamide chemotherapy and tamoxifen (AC->T) in premenopausal...
Association between Mutation and Expression of TP53 as a Potential Prognostic Marker of Triple-Negative Breast Cancer

Kim JY, Park K, Jung HH, Lee E, Cho EY, Lee KH, Bae SY, Lee SK, Kim SW, Lee JE, Nam SJ, Ahn JS, Im YH, Park YH

  • Cancer Res Treat.
  • 2016 Oct;48(4):1338-1350.
  • doi: 10.4143/crt.2015.430
PURPOSE: TP53, the most frequently mutated gene in breast cancer, is more frequently altered in HER2-enriched and basal-like breast cancer. However, no studies have clarified the role of TP53 status...
Identification of Prognostic Risk Factors for Transient and Persistent Lymphedema after Multimodal Treatment for Breast Cancer

Kim M, Shin KH, Jung SY, Lee S, Kang HS, Lee ES, Chung SH, Kim YJ, Kim TH, Cho KH

  • Cancer Res Treat.
  • 2016 Oct;48(4):1330-1337.
  • doi: 10.4143/crt.2015.463
PURPOSE: The purpose of this study is to identify risk factors for transient lymphedema (TLE) and persistent lymphedema (PLE) following treatment for breast cancer. MATERIALS AND METHODS: A total of 1,073...
Comparison of Quality of Life and Sexuality between Cervical Cancer Survivors and Healthy Women

Lee Y, Lim MC, Kim SI, Joo J, Lee DO, Park SY

  • Cancer Res Treat.
  • 2016 Oct;48(4):1321-1329.
  • doi: 10.4143/crt.2015.425
PURPOSE: The purpose of this study is to compare quality of life (QoL) and sexual functioning between sexually active cervical cancer survivors and healthy women. MATERIALS AND METHODS: In this cross-sectional...
The Impact of High-Risk HPV Genotypes Other Than HPV 16/18 on the Natural Course of Abnormal Cervical Cytology: A Korean HPV Cohort Study

So KA, Kim MJ, Lee KH, Lee IH, Kim MK, Lee YK, Hwang CS, Jeong MS, Kee MK, Kang C, Cho CH, Kim SM, Hong SR, Kim KT, Lee WC, Park JS, Kim TJ

  • Cancer Res Treat.
  • 2016 Oct;48(4):1313-1320.
  • doi: 10.4143/crt.2016.013
PURPOSE: The purpose of this study is to evaluate the impact of high-risk human papillomaviruses (HPVs) other than HPV 16/18 on the natural course of atypical squamous cells of undetermined...
TRIM29 Overexpression Promotes Proliferation and Survival of Bladder Cancer Cells through NF-κB Signaling

Tan ST, Liu SY, Wu B

  • Cancer Res Treat.
  • 2016 Oct;48(4):1302-1312.
  • doi: 10.4143/crt.2015.381
PURPOSE: TRIM29 overexpression has been reported in several human malignancies and showed correlation with cancer cell malignancy. The aim of the current study is to examine its clinical significance and...
Poor Preoperative Glycemic Control Is Associated with Dismal Prognosis after Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Korean Multicenter Study

Kang SG, Hwang EC, Jung SI, Yu HS, Chung HS, Kang TW, Kwon DD, Hwang JE, Kim JS, Noh JH, You JH, Kim MK, Oh TH, Seo IY, Baik S, Kim CS, Kang SH, Cheon J

  • Cancer Res Treat.
  • 2016 Oct;48(4):1293-1301.
  • doi: 10.4143/crt.2016.021
PURPOSE: The purpose of this study is to evaluate the effect of diabetes mellitus (DM) and preoperative glycemic control on prognosis in Korean patients with upper tract urothelial carcinoma (UTUC)...
Efficacy and Toxicity of Mammalian Target Rapamycin Inhibitors in Patients with Metastatic Renal Cell Carcinoma with Renal Insufficiency: The Korean Cancer Study Group GU 14-08

Kim KH, Kim JH, Lee JY, Kim HS, Heo SJ, Kim JH, Kim HY, Rha SY

  • Cancer Res Treat.
  • 2016 Oct;48(4):1286-1292.
  • doi: 10.4143/crt.2016.018
PURPOSE: We evaluated the efficacy and toxicity of mammalian target rapamycin inhibitors in Korean patients with metastatic renal cell carcinoma (mRCC) with chronic renal insufficiency not requiring dialysis. MATERIALS AND METHODS:...
Is There a Role for Adjuvant Therapy in R0 Resected Gallbladder Cancer?: A Propensity Score-Matched Analysis

Go SI, Kim YS, Hwang IG, Kim EY, Oh SY, Ji JH, Song HN, Park SH, Park JO, Kang JH

  • Cancer Res Treat.
  • 2016 Oct;48(4):1274-1285.
  • doi: 10.4143/crt.2015.502
PURPOSE: The purpose of this study is to assess the role of adjuvant therapy in stage I-III gallbladder cancer (GBC) patients who have undergone R0 resection. MATERIALS AND METHODS: Clinical data...
Prognostic Factors for Risk Stratification of Patients with Recurrent or Metastatic Pancreatic Adenocarcinoma Who Were Treated with Gemcitabine-Based Chemotherapy

Park I, Choi SJ, Kim YS, Ahn HK, Hong J, Sym SJ, Park J, Cho EK, Lee JH, Shin YJ, Shin DB

  • Cancer Res Treat.
  • 2016 Oct;48(4):1264-1273.
  • doi: 10.4143/crt.2015.250
PURPOSE: The aim of this study was to verify prognostic factors including sarcopenia in patients with recurrent or metastatic pancreatic cancer receiving gemcitabine-based chemotherapy. MATERIALS AND METHODS: Medical records and computed...

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