- Ubiquitination of Aquaporin: in the kidney
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Lee YJ, Kwon TH
- KMID: 1464781
- Electrolyte Blood Press.
- 2009 Jun;7(1):1-4.
- doi: 10.5049/EBP.2009.7.1.1
Ubiquitination is known to be important for endocytosis and lysosomal degradation of aquaporin-2 (AQP2). Ubiquitin (Ub) is covalently attached to the lysine residue of the substrate proteins and activation and... -
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- Vasopressin and Vasopressin Receptor Antagonists
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Oh YK
- KMID: 2052306
- Electrolyte Blood Press.
- 2008 Jun;6(1):51-55.
- doi: 10.5049/EBP.2008.6.1.51
Vasopressin, a neurohypophyseal peptide hormone, is the endogenous agonist at V1a, V1b, and V2 receptors. The most important physiological function of vasopressin is the maintenance of water homeostasis through interaction... -
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- Role of Nitric Oxide in the Regulation of Aquaporin-2 Water Channels in Rat Kidney
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Kim YJ, Yoo GJ, Lee JU
- KMID: 2254388
- Korean J Nephrol.
- 2002 Jul;21(4):525-530.
BACKGROUND: The present study was aimed at investigating whether there is a mechanism exerted by endogenous nitric oxide(NO) in the regulation of aquaporin(AQP) water channels in the kidney. METHODS: Male... -
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- Altered Renal Expression of Aquaporin-2 Water Channels in Two-Kidney, One Clip Hypertension in Rats
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Lee SY
- KMID: 2172442
- Chonnam Med J.
- 2000 Dec;36(4):337-342.
The present study was aimed at examining the regulation of aquaporin-2 (AQP2) water channels in the kidney in two-kidney, one clip (2K1C) hypertension. Rats were made 2K1C hypertensive for 6... -
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- A Minireview on Vasopressin-regulated Aquaporin-2 in Kidney Collecting Duct Cells
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Park EJ, Kwon TH
- KMID: 2052336
- Electrolyte Blood Press.
- 2015 Jun;13(1):1-6.
- doi: 10.5049/EBP.2015.13.1.1
The kidney collecting duct is an important renal tubular segment for the regulation of body water and salt homeostasis. Water reabsorption in the collecting duct cells is regulated by arginine... -
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- Cloning of mouse AQP-CD gene
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Jung JS, Kim JI, Oh SO, Park MY, Bae HR, Lee SH
- KMID: 1554555
- Korean J Physiol Pharmacol.
- 1997 Apr;1(2):195-200.
Water transport in highly-permeable membranes is facilitated by some specialized pathways, which are called aquaporins (AQP). AQP1 (AQP-CHIP) is the first recognized aquaporin identified from red cells and renal proximal tubules. Up until... -
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- Altered Regulation of Aquaporin-2 Water Channels in the Kidney Following Acute Blood Volume Depletion in Rats
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Li YS, Oh Y, Lee S, Lee JU
- KMID: 2079270
- Korean J Nephrol.
- 2003 Jan;22(1):37-42.
BACKGROUND: The present study was aimed to examine the regulation of aquaporin (AQP)-2 water channels in the kidney following blood volume depletion. METHODS: Male Sprague-Dawley rats were acutely blood volume-depleted... -
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- Decreased expression of aquaporin-2 water channels in the kidney in rats treated with reserpine
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Lee JU, Oh YW, Kim S
- KMID: 2071570
- Korean J Physiol Pharmacol.
- 2001 Aug;5(4):307-313.
Whether there exists a Sympathetic neural mechanism regulating the expression of aquaporin (AQP) water channels in the kidney was investigated. Male Sprague-Dawley rats were treated with reserpine (1 mg/kg, IP), and the expression... -
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- Decreased Expression of Aquaporin-2 Water Channels in the Kidney in Rats Treated with Chlorpropamide
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Kim SW, Lee JU, Li YS, Oh YW, Kim NH, Choi KC
- KMID: 2254431
- Korean J Nephrol.
- 2002 May;21(3):375-381.
BACKGROUND: Whether blood glucose levels may change the regulation of aquaporin(AQP) water channels in the kidney was investigated. METHODS: Male Sprague-Dawley rats were treated with chlorpropamide(40 mg/100 g body weight... -
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- Effect of Diet and Water Intake on Aquaporin 2 Function
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Kim JM, Kim TH, Wang T
- KMID: 2163318
- Child Kidney Dis.
- 2016 Apr;20(1):11-17.
- doi: 10.3339/jkspn.2016.20.1.11
Appropriate control of diet and water intake is important for maintaining normal blood pressure, fluid and electrolyte homeostasis in the body. It is relatively understood that the amount of sodium... -
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- A case of primary aldosteronism combined with acquired nephrogenic diabetes insipidus
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Kim K, Lee JH, Kim SC, Cha DR, Kang YS
- KMID: 2224267
- Kidney Res Clin Pract.
- 2014 Dec;33(4):229-233.
- doi: 10.1016/j.krcp.2014.09.001
Aldosterone-producing adrenal adenoma can induce various clinical manifestations as a result of chronic exposure to aldosterone. We report a rare case of a 37-year-old man who complained of general weakness... -
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- Sympathetic Regulation of Aquaporin Water Channels in Rat Kidney
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Lee J, Yoo K, Oh Y, Lim DY
- KMID: 2071594
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):181-185.
Whether there exists a sympathetic neural regulation on the aquaporin (AQP) channels in the kidney was examined. Male Sprague-Dawley rats were used. They were renal nerve denervated by stripping the... -
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- New insights into the transcriptional regulation of aquaporin-2 and the treatment of X-linked hereditary nephrogenic diabetes insipidus
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Jung HJ, Kwon TH
- KMID: 2451864
- Kidney Res Clin Pract.
- 2019 Jun;38(2):145-158.
- doi: 10.23876/j.krcp.19.002
The kidney collecting duct (CD) is a tubular segment of the kidney where the osmolality and final flow rate of urine are established, enabling urine concentration and body water homeostasis.... -
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- Effects of Bilateral Ureteral Obstruction on Renal Aquaporin Expression
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Jeong SJ, Chung SY, Nam KI, Lee SW, Park SS, Ahn KY
- KMID: 2254387
- Korean J Nephrol.
- 2002 Jul;21(4):516-524.
BACKGROUND: Obstruction of urinary tract is common cause of renal disfunction. Recent discovery of aquaporin water channels expressed in the kidney and various organs has faciliated our understanding of water... -
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- A Non-woven Path: Electrospun Poly(lactic acid) Scaffolds for Kidney Tissue Engineering
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Burton TP, Callanan A
- KMID: 2411878
- Tissue Eng Regen Med.
- 2018 Jun;15(3):301-310.
- doi: 10.1007/s13770-017-0107-5
Chronic kidney disease is a major global health problem affecting millions of people; kidney tissue engineering provides an opportunity to better understand this disease, and has the capacity to provide... -
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- Enhanced Atrial Natriuretic Peptide and Nitric Oxide System Following the Treatment with Caffeine in Rats
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Ha JH, Yeum CH, Kim SW, Kim NH, Choi KC, Lee JU
- KMID: 2254463
- Korean J Nephrol.
- 2002 Jan;21(1):123-128.
PURPOSE: The present study was aimed to examine whether caffeine alters the local regulation of atrial natriuretic peptide(ANP) and nitric oxide(NO) systems in the kidney. METHODS: Male Sprague-Dawley rats were treated... -
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- Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160
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Jung HJ, Kwon TH
- KMID: 2406195
- Electrolyte Blood Press.
- 2010 Dec;8(2):59-65.
Akt (protein kinase B (PKB)) is a serine/threonine kinase that acts in the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway. The PI3K/Akt signaling pathway, triggered by growth factors and hormones including vasopressin,... -
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- Water and Sodium Regulation in Heart Failure
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Bae EH, Ma SK
- KMID: 2052317
- Electrolyte Blood Press.
- 2009 Dec;7(2):38-41.
- doi: 10.5049/EBP.2009.7.2.38
Heart failure is the pathophysiological state characterized by ventricular dysfunction and associated clinical symptoms. Decreased cardiac output or peripheral vascular resistance lead to arterial underfilling. That is an important signal... -
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- Two Novel Mutations in the Aquaporin 2 Gene in a Girl with Congenital Nephrogenic Diabetes Insipidus
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Cheong HI, Cho SJ, Zheng SH, Cho HY, Ha IS, Choi Y
- KMID: 2157767
- J Korean Med Sci.
- 2005 Dec;20(6):1076-1078.
- doi: 10.3346/jkms.2005.20.6.1076
Congenital nephrogenic diabetes insipidus (CNDI) is a rare inherited disorder characterized by insensitivity of the kidney to the antidiuretic effect of vasopressin. There are three inheritance patterns of CNDI: the... -
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- Regulation of aquaporin-2 in the kidney : A molecular mechanism of body-water homeostasis
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Kwon TH, Frokiaer J, Nielsen S
- KMID: 2224302
- Kidney Res Clin Pract.
- 2013 Sep;32(3):96-102.
The kidneys play a key role in the homeostasis of body water and electrolyte balance. Aquaporin-2 (AQP2) is the vasopressin-regulated water-channel protein expressed at the connecting tubule and collecting duct,... -
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