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Toxic Epidermal Necrolysis in Polymedicated Patient Treated With Radiotherapy

Perez-Calderon R, Gonzalo-Garijo MA, Corrales-Vargas S, Jimenez-Ferrera G, Rodriguez-Nevado I, Diaz-Delgado M

Temozolomide is an oral alkylating agent indicated for the treatment of patients with glioblastoma multiforme concomitantly with radiotherapy and subsequently as monotherapy treatment. We report the case of a patient...
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An IgE-Mediated Allergic Reaction Caused by Mulberry Fruit

Choi JH, Sim JK, Oh JY, Hur GY, Min KH, Lee SY, Shim JJ, Kang KH

Mulberry (Morus spp.) is a widespread deciduous tree and its fruit is commonly eaten in Korea and eastern Asia. Some reports demonstrate that mulberry fruit is a food allergen in...
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Eosinophils Modulate CD4+ T Cell Responses via High Mobility Group Box-1 in the Pathogenesis of Asthma

Shim EJ, Chun E, Lee HS, Bang BR, Cho SH, Min KU, Park HW

Eosinophils have been reported to modulate T cell responses. Previously, we reported that high-mobility group box 1 protein (HMGB1) played a key role in the pathogenesis of asthma. This study...
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Butter Tolerance in Children Allergic to Cow's Milk

Yanagida N, Minoura T, Kitaoka S

We performed an oral food challenge (OFC) with 10 g of butter (equivalent of 2.9 mL cow's milk) and 25-mL heated cow's milk for 68 children with cow's milk-allergy. Thirty-eight...
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The Association of GSDMB and ORMDL3 Gene Polymorphisms With Asthma: A Meta-Analysis

Zhao CN, Fan Y, Huang JJ, Zhang HX, Gao T, Wang C, Wang T, Hou LF

PURPOSE: ORM1-like 3 (ORMDL3) belongs to a highly conserved protein family which is anchored as transmembrane protein in the endoplasmic reticulum. Gasdermin B (GSDMB) is adjacent to ORMDL3 on chromosome...
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Association Between Antibiotic Exposure, Bronchiolitis, and TLR4 (rs1927911) Polymorphisms in Childhood Asthma

Lee E, Kwon JW, Kim HB, Yu HS, Kang MJ, Hong K, Yang SI, Jung YH, Lee SH, Choi KY, Shin HL, Hong SA, Kim HY, Seo JH, Kim BJ, Lee SY, Song DJ, Kim WK, Jang GC, Shim JY, Hong SJ

PURPOSE: The complex interplay between environmental and genetic factors plays an important role in the development of asthma. Several studies have yielded conflicting results regarding the 2 asthma-related risk factors:...
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Comparison of Intranasal Ciclesonide, Oral Levocetirizine, and Combination Treatment for Allergic Rhinitis

Kim CH, Kim JK, Kim HJ, Cho JH, Kim JS, Kim YD, Lee HM, Kim SW, Cho KS, Lee SH, Rhee CS, Dhong HJ, Rha KS, Yoon JH

PURPOSE: To evaluate the efficacy and safety of once-daily ciclesonide in comparison to both levocetirizine alone, and a ciclesonide/levocetirizine combination in patients with seasonal allergic rhinitis (SAR) and perennial allergic...
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Prevalence of Allergic Rhinitis Among Adults in Urban and Rural Areas of China: A Population-Based Cross-Sectional Survey

Zheng M, Wang X, Bo M, Wang K, Zhao Y, He F, Cao F, Zhang L, Bachert C

PURPOSE: The aim of the present study was to compare the prevalence of self-reported and confirmable allergic rhinitis (AR) with positive skin prick test (SPT) results among adults living in...
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The Quality of Health Information on Allergic Rhinitis, Rhinitis, and Sinusitis Available on the Internet

Chang MY, Kim JW, Rhee CS

PURPOSE: The internet has become one of the most important media outlets used to obtain health information. Therefore, the quality of health information available on the internet is very important....
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Association of Single Nucleotide Polymorphisms in Toll-like Receptor Genes With Asthma Risk: a Systematic Review and Meta-analysis

Tizaoui K, Kaabachi W, Hamzaoui K, Hamzaoui A

PURPOSE: Asthma is a complex disease, with contributions from multiple genes, various genetic backgrounds, and environmental factors. Many human epidemiological studies have demonstrated that single nucleotide polymorphisms (SNPs) in Toll-like...
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In Vitro Evaluation of Allergen Potencies of Commercial House Dust Mite Sublingual Immunotherapy Reagents

Park KH, Son M, Choi SY, Park HJ, Lee JH, Jeong KY, Lee JS, Park JW

PURPOSE: The clinical efficacy of allergen-immunotherapy is known to be dose dependent. However, optimal maintenance dosage has not yet been determined for sublingual immunotherapy (SLIT). Furthermore, since companies adopt their...
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Three-Year Follow-up Results of Sublingual Immunotherapy in Patients With Allergic Rhinitis Sensitized to House Dust Mites

Kim SH, Mun SJ, Han DH, Kim JW, Kim DY, Rhee CS

PURPOSE: This study investigated the long-term efficacy, safety, and compliance associated with sublingual immunotherapy (SLIT) in Korean patients with allergic rhinitis sensitized to house dust mites. METHODS: This is a retrospective...
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Endoplasmic Reticulum Stress and the Related Signaling Networks in Severe Asthma

Kim SR, Lee YC

The endoplasmic reticulum (ER) is a specialized organelle that plays a central role in biosynthesis, correct protein folding, and posttranslational modifications of secretory and membrane proteins. Loss of homeostasis in...
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Natural History and Risk Factors of Atopic Dermatitis in Children

Pyun BY

Atopic dermatitis (AD) is one of the most common inflammatory allergic diseases with pruritic skin lesions particularly in infancy. It is considered to be the first step of atopic march...
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Outcome of Sublingual Immunotherapy in Patients With Allergic Rhinitis Sensitive to House Dust Mites

Kim ST

No abstract available.
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