- Interactive Roles of Activin A in Epidermal Regeneration
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Choi JW, Nam KM, Choi HR, Huh CH, Park KC
- KMID: 2428945
- Ann Dermatol.
- 2018 Dec;30(6):755-757.
- doi: 10.5021/ad.2018.30.6.755
No abstract available. -
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- Mucocutaneous Telangiectasia as a Diagnostic Clue of Hereditary Hemorrhagic Telangiectasia: An Activin Receptor-Like Kinase-1 Mutation in a Korean Patient
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Seo J, Chu H, Lee JS, Kim DY
- KMID: 2171394
- Ann Dermatol.
- 2016 Apr;28(2):264-266.
- doi: 10.5021/ad.2016.28.2.264
No abstract available. -
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- Further Characterization of Activin A-induced IgA Response in Murine B Lymphocytes
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Lee HJ, Kim PH
- KMID: 1474585
- Immune Netw.
- 2009 Aug;9(4):133-137.
- doi: 10.4110/in.2009.9.4.133
We have recently shown that activin A, a member of TGF-beta superfamily, stimulates mouse B cells to express IgA isotype but other isotypes. In the present study, we further characterized... -
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- Activin A Stimulates Mouse APCs to Express BAFF via ALK4-Smad3 Pathway
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Kim JH, Seo GY, Kim PH
- KMID: 1449810
- Immune Netw.
- 2011 Aug;11(4):196-202.
- doi: 10.4110/in.2011.11.4.196
BACKGROUND: B cell-activating factor belonging to the TNF family (BAFF) is primarily expressed by macrophages and dendritic cells, and stimulates B cell proliferation, differentiation, survival, and Ig production. In the... -
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- Recent Topics in Fibrodysplasia Ossificans Progressiva
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Katagiri T, Tsukamoto , Nakachi Y, Kuratani M
- KMID: 2447022
- Endocrinol Metab.
- 2018 Sep;33(3):331-338.
- doi: 10.3803/EnM.2018.33.3.331
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by the formation of heterotopic bone tissues in soft tissues, such as skeletal muscle, ligament, and tendon. It... -
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- Expression Pattern of Smad Proteins in Diffuse Large B-cell Lymphomas
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Go JH
- KMID: 2073840
- Korean J Pathol.
- 2004 Oct;38(5):301-305.
BACKGROUND: Smad proteins mediate the cellular signaling from members of transforming growth factor-beta family (TGF-beta s). Smads 2 and 3 transmit signals from TGF-beta and activin, and Smads 1, 5,... -
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- In vitro Differentiation of Human Embryonic Stem Cells into Definitive Endodermal Cells
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Lim M, Choi D, Kim SJ, Cheong HJ, Won JH
- KMID: 2201874
- J Korean Soc Transplant.
- 2007 Dec;21(2):216-222.
PURPOSE: Whole liver transplantation has limitation including donor shortage and fatal surgical complications. Hepatocyte transplantation, which is simpler and less expensive than whole liver transplantation, allows the use of living... -
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- TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation
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Albers RE, Selesniemi K, Natale DR, Brown TL
- KMID: 2413507
- Int J Stem Cells.
- 2018 Jun;11(1):111-120.
- doi: 10.15283/ijsc17069
BACKGROUND: Transforming growth factor beta (TGF-β) signaling has been shown to control a large number of critical cellular actions such as cell death, differentiation, and development and has been implicated... -
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- Midtrimester Amniotic Fluid Levels and Each Ratio of Activn A, Inhibin A and B in Down's Syndrome and Other Complicated Pregnancies
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Rhu SW, Lee JG, Kim YW, Lee Y, Shin JC, Lew YO, Rha JG, Kim SP
- KMID: 2272367
- Korean J Obstet Gynecol.
- 2004 Jun;47(6):1138-1144.
OBJECTIVE: To evaluate the amniotic fluid levels and each ratio of activin A, inhin A and B in Down's syndrome and other complicated pregnancies. METHODS: This study was performed in... -
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- Microarray Analysis of Differentially Expressed Genes in the Brains of Tubby Mice
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Lee JH, Kim CH, Kim DG, Ahn YS
- KMID: 2071657
- Korean J Physiol Pharmacol.
- 2009 Apr;13(2):91-97.
- doi: 10.4196/kjpp.2009.13.2.91
The tubby mouse is characterized by progressive retinal and cochlear degeneration and late-onset obesity. These phenotypes are caused by a loss-of-function mutation in the tub gene and are shared with... -
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- Porcine Granulosa Cells Produce Gonadotropin Surge Inhibiting Factor (GnSIF) Activity In Vitro
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Seo SH
- KMID: 2261616
- Korean J Obstet Gynecol.
- 1999 Dec;42(12):2815-2820.
OBJECTIVES: It has been identified a novel protein in porcine and bovine follicular fluid termed Gonadotropin Surge Inhibiting Factor (GnSIF) which inhibits GnRH-stimulated LH secretion by pituitary cells in culture.... -
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- Activin A/BMP2 Chimera (AB204) Exhibits Better Spinal Bone Fusion Properties than rhBMP2
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Ryu D, Yoon BH, Oh CH, Kim MH, Kim JY, Yoon SH, Choe S
- KMID: 2428108
- J Korean Neurosurg Soc.
- 2018 Nov;61(6):669-679.
- doi: 10.3340/jkns.2017.0295
OBJECTIVE: To compare the spinal bone fusion properties of activin A/BMP2 chimera (AB204) with recombinant human bone morphogenetic protein (rhBMP2) using a rat posterolateral spinal fusion model. METHODS: The study was... -
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- Influence of Activin and Follistatin on Expression of Insulin-like Growth Factor (IGF)-I, II, Insulin-like Growth Factor Binding Protein (IGFBP)-1, 2, and 3 mRNA in Cultured Mouse Granulosa Cells
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Chae HD, Hong SH, Cho YH, Oh YM, Lee BH, Kim SH, Kim CH, Kang BM
- KMID: 2076847
- Korean J Obstet Gynecol.
- 2003 Mar;46(3):592-599.
OBJECTIVE: To investigate the influence of activin and follistatin on the expression of IGF (insulin-like growth factor)-I, II, IGFBP (insulin-like growth factor binding protein)-1, 2, and 3 mRNA in cultured... -
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- Follistatin N terminus differentially regulates muscle size and fat in vivo
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Zheng H, Qiao C, Tang R, Li J, Bulaklak K, Huang Z, Zhao C, Dai Y, Li J, Xiao X
- KMID: 2394308
- Exp Mol Med.
- 2017 Sep;49(9):e377.
- doi: 10.1038/emm.2017.135
Delivery of follistatin (FST) represents a promising strategy for both muscular dystrophies and diabetes, as FST is a robust antagonist of myostatin and activin, which are critical regulators of skeletal... -
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- Mesenchymal Stem Cells: The Promotion of Endodermal-Induction Using Activin A
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Lee SW, Min SO, Kim SY, Choi SB, Kim HO, Kim KS
- KMID: 1469757
- Korean J Hepatobiliary Pancreat Surg.
- 2009 Dec;13(4):205-214.
PURPOSE: The most important consideration for therapy using MSCs is the differentiation of the target organ's cell type. For in-vitro hepatogenic differentiation of MSCs, the main focus is efficient induction... -
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- Spectrum of Novel Hereditary Hemorrhagic Telangiectasia Variants in an Austrian Patient Cohort
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Koenighofer M, Parzefall , Frohne A, Allen M, Unterberger U, Laccone F, Schoefer C, Frei K, Lucas T
- KMID: 2462737
- Clin Exp Otorhinolaryngol.
- 2019 Nov;12(4):405-411.
- doi: 10.21053/ceo.2019.00304
OBJECTIVES: Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant genetic disorder characterized by pathogenic blood vessel development and maintenance. HHT type 1 (HHT1) and type 2 (HHT2) are caused... -
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- C-terminal-truncated HBV X promotes hepato-oncogenesis through inhibition of tumor-suppressive β-catenin/BAMBI signaling
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Lee S, Lee MJ, Zhang J, Yu GR, Kim DG
- KMID: 2367551
- Exp Mol Med.
- 2016 Dec;48(12):e275.
- doi: 10.1038/emm.2016.107
C-terminal-truncated hepatitis B virus (HBV) X (HBx) (ctHBX) is frequently detected in hepatocellular carcinoma (HCC) through HBV integration into the host genome. However, the molecular mechanisms underlying ctHBx-associated oncogenic signaling... -
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- Cardiomyogenic Potential of Human Adipose Tissue and Umbilical Cord Derived-Mesenchymal Like Stem Cells
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Park S, Kang HM, Kim ES, Kim J, Kim H
- KMID: 2288247
- Korean J Reprod Med.
- 2007 Dec;34(4):239-252.
OBJECTIVES: In the present study, we examined the differentiation potential of human adipose- (HAD) and human umbilical cord-derived mesenchymal like stem cells (HUC) into cardiomyocytes. METHODS: Cells were initially exposed to... -
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- Treatment of renal anemia: Erythropoiesis stimulating agents and beyond
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Biggar P, Kim GH
- KMID: 2416090
- Kidney Res Clin Pract.
- 2017 Sep;36(3):209-223.
- doi: 10.23876/j.krcp.2017.36.3.209
Anemia, complicating the course of chronic kidney disease, is a significant parameter, whether interpreted as subjective impairment or an objective prognostic marker. Renal anemia is predominantly due to relative erythropoietin... -
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- Regulation of FSH Gene Expression and Release in Cultured Rat Anterior Pituitary Cells
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Cheon MS, Park DB, Park YB, Kam KY, Ryu KZ
- KMID: 2199610
- J Korean Soc Endocrinol.
- 2000 Jun;15(2):179-189.
BACKGROUND: FSH is a heterodimeric glycoprotein and is composed of alpha and beta subunits. alpha subunit is common to FSH and LH, while an unique beta subunit determines the biological... -
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