- The potential roles of p53 tumor suppressor in nucleotide excision repair (NER) and base excision repair (BER)
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Seo YR, Jung HJ
- KMID: 1103316
- Exp Mol Med.
- 2004 Dec;36(6):505-509.
The p53 tumor suppressor has long been envisaged to preserve genetic stability by the induction of cell cycle checkpoints and apoptosis. More recently, p53 has been implicated to play roles... -
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- Mitochondrial and DNA damage in bovine somatic cell nuclear transfer embryos
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Hwang IS, Bae HK, Cheong HT
- KMID: 1705552
- J Vet Sci.
- 2013 Sep;14(3):235-240.
- doi: 10.4142/jvs.2013.14.3.235
The generation of reactive oxygen species (ROS) and subsequent mitochondrial and DNA damage in bovine somatic cell nuclear transfer (SCNT) embryos were examined. Bovine enucleated oocytes were electrofused with donor... -
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- Disruption of Microtubules Sensitizes the DNA Damage-induced Apoptosis Through Inhibiting Nuclear Factor kappaB (NF-kappaB) DNA-binding Activity
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Lee H, Jeon J, Ryu YS, Jeong JE, Shin S, Zhang T, Kang SW, Hong JH, Hur GM
- KMID: 1779226
- J Korean Med Sci.
- 2010 Nov;25(11):1574-1581.
- doi: 10.3346/jkms.2010.25.11.1574
The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-kappaB) activity. The exact molecular mechanism by which microtubule rearrangement... -
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- Protective effect of the isoflavone equol against DNA damage induced by ultraviolet radiation to hairless mouse skin
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Widyarini
- KMID: 1089904
- J Vet Sci.
- 2006 Sep;7(3):217-223.
- doi: 10.4142/jvs.2006.7.3.217
Equol, an isoflavonoid metabolite produced from the dietary isoflavone daidzein by the gut microflora in mammals, has been found to protect not only against ultraviolet (UV) radiation-induced cutaneous inflammation and... -
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- Effects of Oxidative DNA Damage and Genetic Polymorphism of the Glutathion Peroxidase 1 (GPX1) and 8-Oxoguanine Glycosylase 1 (hOGG1) on Lung Cancer
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Lee CH, Lee KY, Choe KH, Hong YC, Noh SI, Eom SY, Ko YJ, Zhang YW, Yim DH, Kang JW, Kim H, Kim YD
- KMID: 792399
- J Prev Med Public Health.
- 2006 Mar;39(2):130-134.
OBJECTIVES: Oxidative DNA damage is a known risk factor of lung cancer. The glutathione peroxidase (GPX) antioxidant enzyme that reduces hydrogen peroxide and lipid peroxides plays a significant role... -
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- Identification of mutagenic site of c-H-ras oncogene damaged by N-acetoxyacetylaminofluorene(AAAF)
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Oh SH, Kim KH, Lee SE, Yeh BI
- KMID: 1729587
- Yonsei Med J.
- 1991 Sep;32(3):207-214.
- doi: 10.3349/ymj.1991.32.3.207
A molecularly cloned human cellular H-ras (c-H-ras) oncogene(pbc N1 plasmid) was treated with N-acetoxyacetylaminofluorene (AAAF) in vitro and subcloned into E.coli. This was done to identify the mutational changes at... -
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