Korean J Gastroenterol.  2009 Oct;54(4):220-226. 10.4166/kjg.2009.54.4.220.

Prevalence of Colorectal Adenoma Is Increased in Patients with Gastric Adenoma

• Park SY
• Kim HS
• Yoon KW
• Cho SB
• Lee WS
• Park CH
• Joo YE
• Choi SK
• Rew JS

• KMID: 783227
• DOI: http://doi.org/10.4166/kjg.2009.54.4.220

Abstract

BACKGROUND/AIMS
It has been reported that patients with gastric cancer may be at increased risk of synchronous or metachronous colorectal cancer. However, the incidence of colorectal adenoma in patients with gastric adenoma has not been discussed earlier. The aims of this study were to investigate the incidence of colorectal adenoma and to evaluate the necessity of colonoscopic surveillance in patients with gastric adenoma.
METHODS
We performed colonoscopy in 221 patients with gastric adenoma between January 2002 and June 2008. As a control group, 387 consecutive patients without gastric adenoma on gastroscopy who underwent colonoscopy were included. We retrospectively examined the endoscopic and colonoscopic findings as well as the clinicopathologic features.
RESULTS
Colorectal adenoma were diagnosed in 57.5% (127/221) of the gastric adenoma group and 38.0% (147/387) of the control group (p<0.001). Univariate analysis demonstrated that gender, age, past history of diabetes, and past history of gastric adenoma were associated with the risk of colorectal adenoma. Multivariate analysis demonstrated that gender (male, aOR 2.31, 95% CI 1.61-3.31), age (> or =50 years, aOR 2.47, 95% CI 1.53-4.01), past history of diabetes (aOR 2.35, 95% CI 1.32-4.20), and presence of gastric adenoma (aOR 1.63, 95% CI 1.13-2.36) appeared to be independent risk factors for colorectal adenoma.
CONCLUSIONS
The risk of colorectal adenoma increases significantly in patients with gastric adenoma. We suggest that colonoscopic surveillance may be necessary in patients with gastric adenoma.

Keyword

Gastric adenoma; Colorectal adenoma; Colonoscopy

MeSH Terms

Adenoma/*diagnosis/epidemiology
Age Factors
Aged
Colonoscopy
Colorectal Neoplasms/*diagnosis/epidemiology
Diabetes Mellitus/diagnosis
Female
Humans
Male
Middle Aged
Prevalence
Retrospective Studies
Risk Factors
Sex Factors
Stomach Neoplasms/*diagnosis

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