J Surg Ultrasound.  2023 Nov;10(2):42-51. 10.46268/jsu.2023.10.2.42.

Correlation of Resistive Index Values Using Spectral Doppler Ultrasound with Histopathological Results in Breast Tumors

• Azhar Y
• Candrawinata VS

• KMID: 2553145
• DOI: http://doi.org/10.46268/jsu.2023.10.2.42

Abstract

This study aimed to investigate the diagnostic value of the resistive index (RI) in Spectral Doppler ultrasound for determining breast malignancy, as there is currently no optimal cut-off point for the determination of breast malignancy. The B-mode and Doppler (including Color and Spectral) breast ultrasound examinations of 62 subjects were gathered. These included histopathological results of 31 cases with malignant tumors and 31 cases of benign tumors which served as controls. All examinations and measurements just before the core-needle biopsy of the mass were validated by expert radiologists. All patients were examined using a 7 to 15 MHz GE Logiq linear array transducer. Color Doppler and Spectral Doppler were set on PRF 700-1,000 Hz, maximal gain 85-90%, and wall filler 50-100 Hz. Histopathological results were used as the gold standard. The study's average RI value in benign breast tumors was 0.55 ± 0.16, and the average RI value in malignant breast tumors was 0.97 ± 0.10. According to the Spearman correlation test, the relationship coefficient R is 0.887 (P-value＜0.0001), showing a strong and statistically significant relationship with a positive correlation direction between the increasing RI value on a Spectral Doppler ultrasound examination and the increasing possibility of malignancy in breast tumors. An increase in the value of the RI indicates an increase in the risk of malignancy. Studies relating to this correlation might benefit from future prospective research with a longer follow-up on patients with Breast Imaging-Reporting and Data System (BI-RADS) lesion Category 3.

Keyword

Breast; Breast neoplasms; Doppler ultrasound

Figure

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  Fig. 1 Ultrasound results of benign breast tumor (A) Gray Scale Ultrasound; (B) Spectral Doppler Ultrasound.

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  Fig. 2 Ultrasound results of malig-nant breast tumor (A) and (B) Gray Scale Ultrasound; (C) Spectral Do-ppler Ultrasound.

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